Title: Bortezomib in the elderly patient with plasma cell myeloma who relapsed after auto-HSCT
Abstract:We present a case of 69 year-old woman with plasma cell myeloma who relapsed after autologous hematopoietic stem cell transplantation. The patient was treated with the bortezomib based chemotherapy (1...We present a case of 69 year-old woman with plasma cell myeloma who relapsed after autologous hematopoietic stem cell transplantation. The patient was treated with the bortezomib based chemotherapy (1 PAD [bortezomib, adriamycin, dexamethasone] course with continued PD [adriamycin, dexamethasone] chemotherapy). Due to the hematological toxicity, mainly thrombocytopenia stage 4 according to World Health Organization, the doses of bortezomib were delayed and gradually reduced from of 1.3 mg/m 2 to 1 mg/m 2 , and then to 0.7 mg/m 2 . In addition, the patient required a platelet transfusions. The patient achieved a partial response after 8 courses of PD. Bortezomib is safe and effective and it seems to be valuable option for heavily pretreated patients.Read More
Publication Year: 2015
Publication Date: 2015-01-01
Language: en
Type: article
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