Publication Information

{'id': 'https://openalex.org/W3161334537', 'doi': None, 'title': 'Non-Invasive Diagnosis and Biomarkers in Alcohol-Related Liver Disease', 'display_name': 'Non-Invasive Diagnosis and Biomarkers in Alcohol-Related Liver Disease', 'publication_year': 2020, 'publication_date': '2020-01-01', 'ids': {'openalex': 'https://openalex.org/W3161334537', 'mag': '3161334537'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://www.papersearch.net/google_link/fulltext.asp?file_name=27411308.pdf', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306517315', 'display_name': '춘·추계 학술대회 (KASL)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5061090740', 'display_name': 'Suthat Liangpunsakul', 'orcid': 'https://orcid.org/0000-0002-6504-8123'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Suthat Liangpunsakul', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5061090740'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 60}, 'biblio': {'volume': '2020', 'issue': '1', 'first_page': '84', 'last_page': '85'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11207', 'display_name': 'Alcohol Consumption and Health Effects', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11207', 'display_name': 'Alcohol Consumption and Health Effects', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10351', 'display_name': 'Liver Disease Diagnosis and Treatment', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12910', 'display_name': 'Eicosanoids and Hypertension Pharmacology', 'score': 0.9764, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ethyl-glucuronide', 'display_name': 'Ethyl glucuronide', 'score': 0.76782894}, {'id': 'https://openalex.org/keywords/alcohol-abuse', 'display_name': 'Alcohol abuse', 'score': 0.603596}, {'id': 'https://openalex.org/keywords/liver-disease', 'display_name': 'Liver disease', 'score': 0.5377984}, {'id': 'https://openalex.org/keywords/unit-of-alcohol', 'display_name': 'Unit of alcohol', 'score': 0.5158043}, {'id': 'https://openalex.org/keywords/alcoholic-hepatitis', 'display_name': 'Alcoholic Hepatitis', 'score': 0.50017023}, {'id': 'https://openalex.org/keywords/alcohol-and-health', 'display_name': 'Alcohol and health', 'score': 0.4922928}, {'id': 'https://openalex.org/keywords/steatosis', 'display_name': 'Steatosis', 'score': 0.44329703}, {'id': 'https://openalex.org/keywords/chronic-liver-disease', 'display_name': 'Chronic liver disease', 'score': 0.4333472}], 'concepts': [{'id': 'https://openalex.org/C2780740339', 'wikidata': 'https://www.wikidata.org/wiki/Q416930', 'display_name': 'Ethyl glucuronide', 'level': 4, 'score': 0.76782894}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.76451457}, {'id': 'https://openalex.org/C2777214474', 'wikidata': 'https://www.wikidata.org/wiki/Q147778', 'display_name': 'Cirrhosis', 'level': 2, 'score': 0.71381634}, {'id': 'https://openalex.org/C2777575235', 'wikidata': 'https://www.wikidata.org/wiki/Q558404', 'display_name': 'Alcoholic liver disease', 'level': 3, 'score': 0.6379648}, {'id': 'https://openalex.org/C2781066024', 'wikidata': 'https://www.wikidata.org/wiki/Q156', 'display_name': 'Alcohol', 'level': 2, 'score': 0.6271414}, {'id': 'https://openalex.org/C2780931562', 'wikidata': 'https://www.wikidata.org/wiki/Q7331102', 'display_name': 'Alcohol abuse', 'level': 2, 'score': 0.603596}, {'id': 'https://openalex.org/C2777075537', 'wikidata': 'https://www.wikidata.org/wiki/Q929737', 'display_name': 'Liver disease', 'level': 2, 'score': 0.5377984}, {'id': 'https://openalex.org/C139162783', 'wikidata': 'https://www.wikidata.org/wiki/Q1899871', 'display_name': 'Unit of alcohol', 'level': 4, 'score': 0.5158043}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.50996053}, {'id': 'https://openalex.org/C2780732942', 'wikidata': 'https://www.wikidata.org/wiki/Q3144986', 'display_name': 'Alcoholic hepatitis', 'level': 4, 'score': 0.50017023}, {'id': 'https://openalex.org/C522683910', 'wikidata': 'https://www.wikidata.org/wiki/Q11290178', 'display_name': 'Alcohol and health', 'level': 4, 'score': 0.4922928}, {'id': 'https://openalex.org/C3019635848', 'wikidata': 'https://www.wikidata.org/wiki/Q154', 'display_name': 'Alcohol consumption', 'level': 3, 'score': 0.4689811}, {'id': 'https://openalex.org/C2778772119', 'wikidata': 'https://www.wikidata.org/wiki/Q6058862', 'display_name': 'Fatty liver', 'level': 3, 'score': 0.45429295}, {'id': 'https://openalex.org/C2776175330', 'wikidata': 'https://www.wikidata.org/wiki/Q1365091', 'display_name': 'Steatosis', 'level': 2, 'score': 0.44329703}, {'id': 'https://openalex.org/C2779102576', 'wikidata': 'https://www.wikidata.org/wiki/Q5113984', 'display_name': 'Chronic liver disease', 'level': 3, 'score': 0.4333472}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.43185958}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.37235856}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.1684013}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0748668}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://www.papersearch.net/google_link/fulltext.asp?file_name=27411308.pdf', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306517315', 'display_name': '춘·추계 학술대회 (KASL)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.88}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2908170678', 'https://openalex.org/W2807203253', 'https://openalex.org/W2624196541', 'https://openalex.org/W2396865608', 'https://openalex.org/W2388633315', 'https://openalex.org/W2357325741', 'https://openalex.org/W2348435353', 'https://openalex.org/W2225868680', 'https://openalex.org/W2220070125', 'https://openalex.org/W2167188228', 'https://openalex.org/W2108070227', 'https://openalex.org/W2104892859', 'https://openalex.org/W2080139829', 'https://openalex.org/W2076870744', 'https://openalex.org/W2062338116', 'https://openalex.org/W2047510959', 'https://openalex.org/W2036055356', 'https://openalex.org/W2031475891', 'https://openalex.org/W1995811312', 'https://openalex.org/W1539538252'], 'abstract_inverted_index': {'Alcohol-related': [0], 'liver': [1, 37, 386, 407, 481, 491], 'disease': [2, 38, 408, 471], '(ALD)': [3], 'represents': [4, 342], 'a': [5, 138, 155, 169, 343, 378, 504, 633], 'spectrum': [6, 475], 'of': [7, 36, 50, 64, 70, 75, 109, 172, 184, 189, 212, 233, 345, 368, 380, 390, 405, 417, 476, 525, 547, 554, 566, 570, 602], 'clinical': [8, 230, 279, 574, 612], 'illness': [9], 'and': [10, 17, 34, 72, 89, 121, 146, 236, 251, 301, 315, 435, 497, 506, 535, 573, 595, 622, 628, 635], 'pathological': [11], 'change': [12], 'in': [13, 43, 137, 154, 165, 209, 229, 255, 278, 319, 331, 334, 348, 365, 473, 514, 624, 632], 'individuals': [14], 'with': [15, 40, 55, 181, 384, 392, 426, 429, 516, 586, 590, 639], 'acute': [16], 'chronic': [18, 287, 385, 406], 'alcohol': [19, 59, 76, 205, 226, 238, 270, 288, 338, 356, 571, 578], 'consumption.': [20], 'Patients': [21], 'may': [22, 29, 274], 'have': [23, 194, 219, 581], 'minimal': [24], 'abnormalities': [25], 'from': [26, 363, 411], 'steatosis': [27, 513], 'or': [28, 46, 98, 105, 177, 241, 409, 458], 'develop': [30], 'more': [31, 132, 141, 150, 158, 178], 'severe': [32], 'signs': [33, 404], 'symptoms': [35], 'associated': [39, 180], 'inflammation': [41], 'seen': [42, 395, 420], 'alcoholic': [44, 567], 'hepatitis': [45, 431], 'cirrhosis.': [47], 'The': [48, 465, 545], 'risk': [49, 101, 183], 'ALD': [51, 71, 393, 427, 441, 461, 625, 640], 'is': [52, 78, 126, 207, 328, 370, 442, 462, 483, 494, 503, 556, 606, 614], 'closely': [53], 'related': [54], 'the': [56, 65, 73, 100, 107, 115, 190, 210, 234, 243, 320, 359, 366, 374, 415, 470, 474, 533, 541, 552, 564, 591, 611], 'per': [57, 144, 161, 175], 'capita': [58], 'consumption;': [60], 'however,': [61, 532], 'careful': [62], 'study': [63, 379], 'relationship': [66], 'between': [67], 'development/natural': [68], 'history': [69, 569], 'quantity': [74], 'consumed': [77], 'almost': [79], 'impossible,': [80], 'because': [81, 492], 'data': [82], 'collection': [83], 'always': [84, 608], 'involves': [85], 'numerous': [86], 'broad': [87], 'assumptions': [88], 'rough': [90], 'estimates.': [91], 'Drinking': [92], 'becomes': [93], 'excessive': [94, 124, 204, 225, 337], 'when': [95, 448], 'it': [96, 493, 519], 'causes': [97], 'elevates': [99], 'for': [102, 192, 200, 203, 224, 286, 460, 489, 511, 563, 583], 'alcohol-related': [103], 'problems': [104], 'complicates': [106], 'management': [108], 'other': [110], 'health': [111], 'problems.': [112], 'According': [113], 'to': [114, 222, 267, 284, 453, 550, 597, 643], 'National': [116], 'Institute': [117], 'on': [118, 469, 540], 'Alcohol': [119], 'Abuse': [120], 'Alcoholism': [122], '(NIH/NIAAA),': [123], 'drinking': [125], 'defined': [127, 399], 'as': [128, 400, 433, 485], 'men': [129], 'who': [130, 148], 'drink': [131, 149], 'than': [133, 142, 151, 159], '4': [134], 'standard': [135], 'drinks': [136, 153], 'day': [139, 156, 176], '(or': [140, 157], '14': [143], 'week)': [145], 'women': [147], '3': [152, 588], '7': [160], 'week).': [162], 'Early': [163, 456], 'studies': [164, 631], 'France': [166], 'suggested': [167], 'that': [168, 440], 'long-term': [170], 'consumption': [171, 572], '80': [173], 'grams': [174], 'was': [179], 'increased': [182], 'cirrhosis': [185], 'but': [186, 262, 518], 'subsequent': [187], 'estimates': [188], 'threshold': [191], 'harm': [193], 'been': [195, 220, 260], 'below': [196], 'this': [197], 'level,': [198], 'especially': [199], 'women.': [201], 'Screening': [202], 'use': [206, 227, 273, 289, 546, 579], 'important': [208, 561], 'diagnosis': [211, 565, 613, 621], 'ALD.': [213, 477], 'Besides': [214], 'questionnaires,': [215], 'several': [216, 324, 527], 'laboratory': [217], 'tests': [218, 283, 311, 529], 'used': [221], 'screen': [223, 488], '(EAU)': [228], 'practice.': [231], 'Determination': [232], 'breath': [235], 'blood': [237, 256, 321, 528], 'concentration': [239], '(BAC)': [240], 'by': [242], 'highly': [244], 'specific': [245, 266, 619], 'direct': [246], 'markers': [247], 'ethyl': [248, 252], 'glucuronide': [249], '(EtG)': [250], 'sulphate': [253], '(EtS)': [254], 'and/or': [257], 'urine': [258], 'has': [259], 'used,': [261], 'they': [263], 'are': [264, 290, 352, 530, 537, 559, 626, 641], 'only': [265, 388], 'very': [268], 'recent': [269], 'ingestion;': [271], 'its': [272], 'not': [275, 607], 'be': [276], 'useful': [277], 'situation.': [280], 'Other': [281], 'lab': [282], 'screening': [285, 459], 'gamma': [291], 'glutaryl': [292], 'transferase': [293], '(GGT),': [294], 'aspartate': [295], 'aminotransferase': [296, 299, 599], '(AST),': [297], 'alanine': [298, 598], '(ALT),': [300], 'mean': [302], 'corpuscular': [303], 'volume': [304], '(MCV).': [305], 'Despite': [306], 'their': [307], 'common': [308], 'use,': [309], 'these': [310, 645], 'revealed': [312], 'low': [313], 'sensitivities': [314], 'specificities.': [316], 'Transferrin': [317], 'molecules': [318], 'usually': [322], 'contain': [323], 'carbohydrate': [325], 'components,': [326], 'which': [327, 351], 'reduced,': [329], 'resulting': [330], 'an': [332, 486], 'increase': [333], '%CDT,': [335], 'among': [336], 'users.': [339], 'Phosphatidylethanol': [340], '(PEth)': [341], 'group': [344], 'phospholipids': [346], 'present': [347], 'cell': [349], 'membranes,': [350], 'formed': [353], 'directly': [354], 'after': [355], 'intake': [357], 'via': [358], 'enzyme': [360], 'phospholipase': [361], 'D': [362], 'phosphatidylcholine': [364], 'presence': [367], 'alcohol.\nALD': [369], 'rarely': [371], 'detected': [372, 444], 'at': [373, 396, 421, 445], 'early': [375, 397], 'stage.': [376], 'In': [377], '3,500': [381], 'patients': [382, 391, 418, 449, 515, 638], 'worldwide': [383], 'disease,': [387], '3.8%': [389], 'were': [394, 419, 424], 'stages': [398, 423, 447], 'those': [401, 425], 'without': [402], 'any': [403], 'complications': [410], 'portal': [412], 'HTN.': [413], 'Whereas': [414], 'majority': [416], 'advanced': [422], 'compared': [428], 'viral': [430], 'such': [432], 'HCV': [434], 'HBV.': [436], 'These': [437], 'results': [438], 'indicate': [439], 'normally': [443], 'later': [446], 'require': [450], 'hospitalization': [451], 'owing': [452], 'liver-related': [454], 'complications.': [455], 'detection': [457], 'therefore': [463], 'important.': [464], 'diagnostic': [466], 'tool': [467], 'depends': [468], 'stage': [472], 'For': [478, 523], 'hepatic': [479], 'steatosis,': [480], 'ultrasound': [482], 'accepted': [484], 'initial': [487], 'fatty': [490], 'non-invasive,': [495], 'inexpensive': [496], 'widely': [498], 'available.': [499], 'Controlled': [500], 'attenuation': [501], 'parameter': [502], 'simple': [505], 'promising': [507], 'new': [508], 'bedside': [509], 'technique': [510], 'diagnosing': [512], 'ALD,': [517], 'requires': [520], 'further': [521], 'validation.': [522], 'evaluation': [524], 'fibrosis,': [526], 'available;': [531], 'sensitivity': [534], 'specificity': [536], 'varied': [538], '(depending': [539], 'cut': [542], 'off': [543], 'values).': [544], 'transient': [548], 'elastography': [549], 'determine': [551], 'degree': [553], 'fibrosis': [555], 'promising.': [557], 'There': [558], '2': [560], 'components': [562], 'hepatitis,': [568], 'presentation/laboratory': [575], 'tests.': [576], 'Excessive': [577], 'should': [580], 'occurred': [582], '>6': [584], 'months,': [585], 'mg/dL': [589], 'AST': [592, 596], '(>50': [593], 'IU/mL),': [594], '(ALT)': [600], 'ratio': [601], '>1.5.': [603], 'Liver': [604], 'biopsy': [605], 'required': [609], 'unless': [610], 'unclear.': [615], 'To': [616], 'date,': [617], 'no': [618], 'non-invasive': [620], 'biomarkers': [623], 'reliable': [627], 'validated.': [629], 'Systematic': [630], 'large': [634], 'well': [636], 'characterized': [637], 'needed': [642], 'address': [644], 'shortcomings.': [646]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3161334537', 'counts_by_year': [], 'updated_date': '2024-12-27T05:04:41.636991', 'created_date': '2021-05-24'}