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'https://openalex.org/W3139867735', 'https://openalex.org/W3032080060', 'https://openalex.org/W3030841261', 'https://openalex.org/W3030620851', 'https://openalex.org/W3029943246', 'https://openalex.org/W2979348315', 'https://openalex.org/W2590609812', 'https://openalex.org/W2393507373', 'https://openalex.org/W2387453307', 'https://openalex.org/W2370708434', 'https://openalex.org/W2355710759', 'https://openalex.org/W2352235940', 'https://openalex.org/W2349985059', 'https://openalex.org/W2247114733', 'https://openalex.org/W2091760567', 'https://openalex.org/W2084190154', 'https://openalex.org/W2034045660'], 'abstract_inverted_index': {'瞄准:为了评估': [0], 'RNA': [1], '干扰(RNAi': [2], ')': [3, 7], '的效果,调停了信号': [4], 'transduction': [5], '的沉默和抄写(STAT': [6], '的激活': [8], '3': [9], '在在': [10], 'vitro': [11, 26], '并且在': [12], 'vivo': [13], '的人的胰腺的癌症房间的生长上。方法:STAT3': [14], '特定的': [15], 'shRNA': [16], '习惯于沉默在胰腺的癌症房间线': [17], 'SW1990': [18, 31, 52], '的': [19, 23, 36, 49], 'STAT3': [20, 22, 28, 35, 48, 59], '的表示。对': [21], 'RNAi': [24, 33, 37, 50, 57], '的反生长效果在裸体老鼠在': [25], '并且在试验性的癌症异种皮移植被学习。涉及': [27], '发信号的潜在的小径用反向的抄写聚合酶链反应并且西方的弄污被检测。结果:STAT3': [29], '的表示在': [30], '房间用': [32], '被禁止。对': [34], '禁止了房间增长,导致了房间': [38], 'apoptosis': [39], '并且当时,显著地减少了': [40], 'CyclinD1': [41], '和': [42], 'Bcl-xL': [43], '的层次与相比父母并且控制': [44], 'vector-transfected': [45], '房间。在': [46], 'vivo,实验证明对': [47], '禁止了': [51], '细胞的': [53], 'tumorigenicity': [54], '并且当它直接被注入肿瘤时,显著地压制了肿瘤生长。结论:STAT3': [55], '发信号小径戏在胰腺的癌症的前进的一个重要角色,和用': [56], '技术的': [58], '基因的沉默可以是为胰腺的癌症的治疗的一种新奇治疗学的选择。': [60]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3147063983', 'counts_by_year': [], 'updated_date': '2024-09-19T07:25:09.993999', 'created_date': '2021-04-13'}