Title: Influence of limited fluid resuscitation on blood system in rats with hemorrhagic shock
Abstract:Objective To investigate the effect of limited fluid resuscitation on blood system in white rats with hemorrhagic shock.Methods The model of hemorrhagic shock in white rats was established.The hemorrh...Objective To investigate the effect of limited fluid resuscitation on blood system in white rats with hemorrhagic shock.Methods The model of hemorrhagic shock in white rats was established.The hemorrhagic shock of white rats was resuscitated by adopting two different transfusion means of limited fluid transfusion and traditional transfusion.The changes of HGB,HCT,PT,APTT and Fbg at various time points were compared between the two groups.Results At 120 min after the establishment of shock model,HGB,HCT and Fbg (142.5±12.3)g/L,(40.8±3.2)%and (3.2±1.5)g/L,respectively) were significantly increased,while PT and APTT (11.8±2.6)s and (57.2±8.1)s were significantly shorter in the limited fluid transfusion group than those in the raditional resuscitation group (P<0.05).Conclusions Limited fluid resuscitation can significantly stabilize HCT.maintain HGB,ease the prolonged PT AND APTT times,and prevent the decrease of Fbg concentration.It is an ideal resuscitation means for the hemorrhagic shock.
Key words:
Limited fluid resuscitation; Blood system; Hemorrhagic shockRead More
Publication Year: 2008
Publication Date: 2008-11-26
Language: en
Type: article
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