Title: Effect and curative effect observation of Xiyanping injection on serum inflammatory cytokines of lobar pneumonia children
Abstract: Objective
To observe the effect and curative effect of Xiyanping injection on serum inflammatory cytokines of lobar pneumonia children.
Methods
The total of 104 children with lobar pneumonia were selected and randomly divided into control group and experiment group, with 52 cases in each group. All patients were given conventional anti-infection and symptomatic treatment, children in the experiment group were given Xiyanping injection additionally. The serum levels of TNF-α, IL-6, IL-8, IL-10 and HMGB1 in the two groups before and after treatment and the clinical curative effects were compared.
Results
After the treatment of Xiyanping injection, the serum levels of TNF-α, IL-6, IL-8, IL-10 and HMGB1 in the experiment group were significantly lower than those in the control group (P<0.01). The duration of fever, remission duration of cough and absorption time of lung shadow in the experiment group were significantly shorter than those in the control group (P<0.01).
Conclusions
Xiyanping injection can significantly reduce the serum levels of inflammatory factors of lobar pneumonia children and improve their immune function, and the effect is exact.
Key words:
Xiyanping; Lobar pneumonia; Tumor necrosis factor-α; Interleukin; High mobility group box-1
Publication Year: 2017
Publication Date: 2017-05-10
Language: en
Type: article
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