Publication Information

{'id': 'https://openalex.org/W3030729391', 'doi': 'https://doi.org/10.3760/cma.j.issn.1673-436x.2018.04.011', 'title': 'Detection of epidermal growth factor receptor-T790M mutation in circulating tumor DNA of lung cancer patients for tyrosine kinase inhibitor acquired resistance', 'display_name': 'Detection of epidermal growth factor receptor-T790M mutation in circulating tumor DNA of lung cancer patients for tyrosine kinase inhibitor acquired resistance', 'publication_year': 2018, 'publication_date': '2018-02-20', 'ids': {'openalex': 'https://openalex.org/W3030729391', 'doi': 'https://doi.org/10.3760/cma.j.issn.1673-436x.2018.04.011', 'mag': '3030729391'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN131368201804/1032773.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764708976', 'display_name': 'Chinese Journal of Asthma', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5047485120', 'display_name': 'Xiaojiao Yang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I44673925', 'display_name': 'Inner Mongolia Medical University', 'ror': 'https://ror.org/01mtxmr84', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I44673925']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Xiaojiao Yang', 'raw_affiliation_strings': ['Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, China', 'institution_ids': ['https://openalex.org/I44673925']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5047485120'], 'corresponding_institution_ids': ['https://openalex.org/I44673925'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 62}, 'biblio': {'volume': '38', 'issue': '4', 'first_page': '297', 'last_page': '300'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10417', 'display_name': 'Lung Cancer Treatments and Mutations', 'score': 0.9922, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10417', 'display_name': 'Lung Cancer Treatments and Mutations', 'score': 0.9922, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11287', 'display_name': 'Cancer Genomics and Diagnostics', 'score': 0.9775, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10696', 'display_name': 'Gastric Cancer Management and Outcomes', 'score': 0.9766, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/t790m', 'display_name': 'T790M', 'score': 0.94324774}, {'id': 'https://openalex.org/keywords/liquid-biopsy', 'display_name': 'Liquid biopsy', 'score': 0.59854984}], 'concepts': [{'id': 'https://openalex.org/C2777930144', 'wikidata': 'https://www.wikidata.org/wiki/Q25100112', 'display_name': 'T790M', 'level': 5, 'score': 0.94324774}, {'id': 'https://openalex.org/C2779438470', 'wikidata': 'https://www.wikidata.org/wiki/Q424401', 'display_name': 'Epidermal growth factor receptor', 'level': 3, 'score': 0.81355816}, {'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.75574934}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.69528085}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.68388456}, {'id': 'https://openalex.org/C2779529041', 'wikidata': 'https://www.wikidata.org/wiki/Q22349364', 'display_name': 'Liquid biopsy', 'level': 3, 'score': 0.59854984}, {'id': 'https://openalex.org/C42362537', 'wikidata': 'https://www.wikidata.org/wiki/Q87099740', 'display_name': 'Tyrosine kinase', 'level': 3, 'score': 0.53572893}, {'id': 'https://openalex.org/C2776362946', 'wikidata': 'https://www.wikidata.org/wiki/Q424374', 'display_name': 'Epidermal growth factor', 'level': 3, 'score': 0.4736375}, {'id': 'https://openalex.org/C2778820342', 'wikidata': 'https://www.wikidata.org/wiki/Q906415', 'display_name': 'Tyrosine-kinase inhibitor', 'level': 3, 'score': 0.4708388}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.4537492}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.43546447}, {'id': 'https://openalex.org/C2780580887', 'wikidata': 'https://www.wikidata.org/wiki/Q417824', 'display_name': 'Gefitinib', 'level': 4, 'score': 0.41555834}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.31030852}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.26410934}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.24735609}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.1876741}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.117646664}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN131368201804/1032773.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764708976', 'display_name': 'Chinese Journal of Asthma', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.79}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3141931277', 'https://openalex.org/W3111641268', 'https://openalex.org/W3108562465', 'https://openalex.org/W3031530718', 'https://openalex.org/W2964322592', 'https://openalex.org/W2947857118', 'https://openalex.org/W2947055267', 'https://openalex.org/W2947028469', 'https://openalex.org/W2792211948', 'https://openalex.org/W2524326668', 'https://openalex.org/W2516816493', 'https://openalex.org/W2377275441', 'https://openalex.org/W2297575142', 'https://openalex.org/W2185181061', 'https://openalex.org/W2170669428', 'https://openalex.org/W2162186250', 'https://openalex.org/W2158043094', 'https://openalex.org/W2057855027', 'https://openalex.org/W2011750233', 'https://openalex.org/W2002937040'], 'abstract_inverted_index': {'Epidermal': [0], 'growth': [1, 143, 149], 'factor': [2, 144, 150], 'receptor': [3], '(EGFR)': [4], 'is': [5, 61, 74], 'closely': [6], 'related': [7], 'to': [8, 43, 109], 'the': [9, 14, 23, 28, 48, 59, 123], 'occurrence': [10], 'of': [11, 16, 25, 30, 47, 112, 125], 'lung': [12, 20, 33, 45, 135], 'cancer.As': [13], 'treatment': [15, 53], 'advanced': [17], 'non-small': [18], 'cell': [19, 92], 'cancer': [21, 34, 136], 'reached': [22], 'level': [24], 'molecular': [26], 'biology,': [27], 'relationship': [29], 'EGFR': [31, 63], 'with': [32, 65, 83, 134], 'bacame': [35], 'clear,': [36], 'EGFR-tyrosine': [37], 'kinase': [38, 152], 'inhibitor': [39, 153], '(TKI)': [40], 'was': [41], 'developed': [42], 'treat': [44], 'cancer.Most': [46], 'patients': [49, 133], 'received': [50], 'EGFR-TKI': [51], 'first-line': [52], 'have': [54, 101], 'acquired': [55], 'drug': [56], 'resistance,': [57], 'and': [58, 98, 117], 'mechanism': [60], 'mainly': [62], 'gene': [64], 'resistance': [66], 'mutation.The': [67], 'traditional': [68], 'detection': [69, 124], 'method': [70], 'for': [71, 137], 'this': [72], 'mutation': [73, 127], 'tissue': [75, 81], 'biopsy.There': [76], 'are': [77], 'some': [78], 'limitations': [79], 'in': [80, 105, 128, 132], 'biopsy.Compared': [82], 'that,': [84], 'liquid': [85], 'biopsies': [86], 'such': [87], 'as': [88], 'circulating': [89, 95], 'tumor': [90, 96, 119, 130, 147], 'cells,': [91], 'free': [93], 'DNA,': [94], 'DNA': [97, 131], 'so': [99], 'on': [100], 'attracted': [102], 'much': [103], 'attention': [104], 'recent': [106], 'years': [107], 'due': [108], 'their': [110], 'advantages': [111], 'minimal': [113], 'invasion,': [114], 'conveniency,': [115], 'repeatability,': [116], 'reducing': [118], 'heterogeneity.This': [120], 'paper': [121], 'reviews': [122], 'EGFR-T790M': [126], 'circulation': [129], 'TKI': [138], 'aquired': [139], 'resistance.\r\n\r\n\r\nKey': [140], 'words:': [141], '\r\nEpidermal': [142], 'receptor-T790M': [145], 'mutation;\xa0Circulating': [146], 'DNA;\xa0Epidermal': [148], 'receptor-tyrosine': [151]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030729391', 'counts_by_year': [], 'updated_date': '2024-12-24T07:12:29.695960', 'created_date': '2020-06-05'}