Publication Information

{'id': 'https://openalex.org/W3030517493', 'doi': 'https://doi.org/10.3760/cma.j.issn.0254-1416.2016.04.017', 'title': 'Role of Nrf2/ARE singling pathway in reduction of myocardial ischemia-reperfusion injury by zinc sulfate preconditioning in rats', 'display_name': 'Role of Nrf2/ARE singling pathway in reduction of myocardial ischemia-reperfusion injury by zinc sulfate preconditioning in rats', 'publication_year': 2016, 'publication_date': '2016-04-20', 'ids': {'openalex': 'https://openalex.org/W3030517493', 'doi': 'https://doi.org/10.3760/cma.j.issn.0254-1416.2016.04.017', 'mag': '3030517493'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN131073201604/904785.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764665209', 'display_name': 'Zhonghua mazuixue zazhi', 'issn_l': '0254-1416', 'issn': ['0254-1416'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 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'https://openalex.org/W3030413861', 'https://openalex.org/W3029854886', 'https://openalex.org/W3029545490', 'https://openalex.org/W3028888158', 'https://openalex.org/W3028778539', 'https://openalex.org/W3028703100', 'https://openalex.org/W2752275381', 'https://openalex.org/W2750967715', 'https://openalex.org/W2588463539', 'https://openalex.org/W2384738281', 'https://openalex.org/W2354847270'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'evaluate': [1], 'the': [2, 23, 37, 93, 109, 149, 160, 185, 202, 224, 236, 242, 255, 264, 291, 306, 317, 343, 358, 363, 377, 398], 'role': [3], 'of': [4, 16, 91, 107, 124, 138, 156, 175, 183, 227, 229, 238, 244, 254, 257, 263, 266, 308, 319, 360, 365], 'nuclear': [5], 'factor': [6, 9, 407], 'erythroid': [7], '2-related': [8], '2(Nrf2)/antioxidant': [10], 'response': [11], 'element(ARE)signaling': [12], 'pathway': [13, 82, 396], 'in': [14, 22, 36, 51, 101, 126, 211, 310, 331, 383, 397], 'reduction': [15], 'myocardial': [17, 248, 258, 389], 'ischemia-reperfusion(I/R)injury': [18], 'by': [19, 121, 135, 143, 172], 'ischemic': [20, 73, 78, 131], 'preconditioning': [21, 74, 132, 387], 'rats.\r\n\r\n\r\nMethods\r\nHealthy': [24], 'male': [25], 'Sprague-Dawley': [26], 'rats,': [27], 'weighing': [28], '250-300': [29], 'g,': [30], 'aged': [31], '4-6': [32], 'months,': [33], 'were': [34, 40, 57, 95, 111, 162, 187, 205, 250, 297, 349, 380], 'used': [35], 'study.Their': [38], 'hearts': [39, 56, 94, 110, 161, 186], 'excised,': [41], 'and': [42, 77, 158, 201, 223, 240, 260, 273, 278, 284, 295, 300, 312, 316, 323, 326, 334, 347, 352, 362, 370, 376], 'retrogradely': [43], 'perfused': [44, 97, 188], 'with': [45, 189, 288, 340], 'K-H': [46, 190], 'solution': [47, 191], 'at': [48, 117, 168, 235, 305, 357], '37': [49], '℃': [50, 170], 'a': [52, 64], 'Langendorff': [53], 'apparatus.Forty': [54], 'isolated': [55], 'randomly': [58], 'divided': [59], 'into': [60], '4': [61], 'groups(n=10': [62], 'each)using': [63], 'random': [65], 'number': [66], 'table:': [67], 'control': [68], 'group(group': [69, 75, 85], 'C),': [70], 'I/R': [71, 311, 390], 'group,': [72], 'IPC),': [76], 'preconditioning+': [79], 'Nrf2/ARE': [80, 394], 'signaling': [81, 395], 'blocker': [83], 'luteolin': [84], 'IPC+': [86, 178, 313, 335, 385], 'L).': [87], 'After': [88, 104], '20': [89, 105, 154, 181], 'min': [90, 100, 106, 115, 123, 155, 166, 174, 182, 198], 'equilibration,': [92, 108, 157, 184], 'continuously': [96], 'for': [98, 196, 252, 261], '100': [99], 'group': [102, 127, 129, 177, 212, 289, 341, 384], 'C.': [103], 'subjected': [112, 163], 'to': [113, 164, 207], '40': [114, 165], 'ischemia': [116, 141, 167], '32': [118, 169], '°C': [119], 'followed': [120, 142, 171], '60': [122], 'reperfusion': [125, 146, 309, 403], 'I/R.In': [128], 'IPC,': [130, 342], 'was': [133, 302, 328, 354, 372], 'induced': [134], '6': [136], 'cycles': [137], '10': [139, 144], 's': [140, 145], 'starting': [147], 'from': [148], 'time': [150], 'point': [151], 'immediately': [152], 'after': [153, 180], 'then': [159], '58': [173], 'reperfusion.In': [176], 'L,': [179], 'containing': [192], 'lueolin': [193], '50': [194], 'μmol/L': [195], '3': [197], 'before': [199], 'ischemia,': [200], 'other': [203], 'treatments': [204], 'similar': [206], 'those': [208], 'previously': [209], 'described': [210], 'IPC.Left': [213], 'ventricular': [214, 218, 231, 247], 'developed': [215], 'pressure(LVDP),': [216], 'left': [217, 230, 246], 'end-diastolic': [219], 'pressure(LVDEP),': [220], 'heart': [221], 'rate(HR),': [222], 'maximum': [225], 'rate': [226], 'increase': [228], 'pressure(+': [232], 'dp/dtmax)were': [233], 'recorded': [234], 'end': [237, 243, 307, 359], 'equilibration': [239], 'reperfusion.At': [241], 'reperfusion,': [245, 361], 'tissues': [249], 'obtained': [251], 'examination': [253], 'ultrastructure': [256], 'cells': [259], 'determination': [262], 'expression': [265, 318, 364], 'Nrf2,': [267, 320], 'heme': [268], 'oxygenase-1(HO-1),': [269], 'quinone': [270], 'oxidoreductase': [271], '1(NQO1),': [272], 'superoxide': [274], 'dismutase': [275], '1(SOD1)': [276], 'mRNA': [277, 325, 369], 'protein(by': [279], 'real-time': [280], 'polymerase': [281], 'chain': [282], 'reaction': [283], 'Western': [285], 'blot,': [286], 'respectively).\r\n\r\n\r\nResults\r\nCompared': [287], 'C,': [290], 'HR,': [292, 344], '+': [293, 345], 'dp/dtmax': [294, 346], 'LVDP': [296, 348], 'significantly': [298, 303, 329, 350, 355, 373, 381], 'decreased,': [299, 351], 'LVEDP': [301, 353], 'increased': [304, 356], 'L': [314, 336], 'groups,': [315], 'HO-1,': [321, 366], 'NQO1': [322], 'SOD1': [324, 368], 'protein': [327, 371], 'up-regulated': [330], 'I/R,': [332], 'IPC': [333], 'groups(P': [337], '0.05).': [338], 'Compared': [339], 'NQO1,': [367], 'down-regulated(P': [374], '0.05),': [375], 'pathological': [378], 'changes': [379], 'aggravated': [382], 'L.\r\n\r\n\r\nConclusion\r\nIschemic': [386], 'reduces': [388], 'injury': [391], 'through': [392], 'activating': [393], 'rats.\r\n\r\n\r\nKey': [399], 'words:': [400], '\r\nIschemic': [401], 'preconditioning;\xa0Myocardial': [402], 'injury;\xa0Nuclear': [404], 'factor-E2': [405], 'related': [406], '2;\xa0Response': [408], 'elements': [409]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030517493', 'counts_by_year': [], 'updated_date': '2024-12-15T08:17:22.030256', 'created_date': '2020-06-05'}