Title: Advance in research of microRNA's application and relationship between microRNA and tumor
Abstract: MicroRNA(miRNA)is a kind of 22 nt endogenous small non-coding single strand RNA and is universally present in animals and plants.It can suppress the expression of target genes at post-transcription al level by complementary biding to the 3'UTR of target mRNAs.Recent studies indicate that microRNA is closely associated with tumorigenesis,differentiation,metastasis and relapse.MicroRNA might act as a new biomarker of tumor diagnosis and a new target of tumor gene therapy.
Key words:
miRNA; tumor; biomarker; gene therapy
Publication Year: 2009
Publication Date: 2009-03-31
Language: en
Type: article
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