Title: Contrast research of laryngeal mask self-ventilation and endotracheal intubation sevoflurane inhalation anesthesia in modified radical mastectomy
Abstract: Objective To compare the application of laryngeal mask self-ventilation and endotracheal intubation inhalation of sevoflurane anesthesia in modified radical mastectomy. Methods Sixty cases of breast cancer under general anesthesia were randomly divided into endotracheal intubation group (E group) and LMA group (L group), 30 cases of each group. Induction of anesthesia: E group followed by intravenous injection of midazolam 0.05 mg/kg, propofol 1.5 mg/kg, vecuronium 0.1 mg/kg, as well as remifentanil 1.5 μg/kg. Jaw relaxation after tracheal intubation. L group induced by cyclic breathing circuit, so that loop filled with 7% sevoflurane gas inhalation 7% to 8% sevoflurane to the infusion-style dropper. And it be added to remifentanil 1.5 μg/kg. Laryngeal mask airway insertion after jaw relaxation. Anesthesia maintenance: E group of conventional intravenous administration, L group to inhalation of sevoflurane-based. Observe and record the hemodynamic changes, end-tidal carbon dioxide partial pressure (PETCO2), bispectral index (BIS) and the adverse effects of anesthesia recovery each time point during anesthesia. Each group were randomly selected 10 patients who were collected blood plasma concentrations of N and NE at different time point. Results The results of HR, SBP, DBP and plasma E, NE concentration in the pre-induction had no statistically significant difference between the two groups (P>0.05).HR, SBP, DBP and plasma E, NE concentration had statistically significance difference in E group when trachea intubation and pulled out compared with before induction and L group (P<0.05). HR, SBP, DBP and plasma E, NE concentration had no significant difference in L group at each time point (P>0.05). Anesthesia recovery adverse reactions (restlessness, cough, a hoarse voice) in E group had statistically significance difference than that in L group (P<0.05). Conclusions The effects of Op Le laryngeal mask inhalation of sevoflurane used in spontaneous ventilation modified radical mastectomy in breast cancer is exact, wake up quickly and securely, and has lighter-anesthesia stress response and less complication than trachea intubation.
Key words:
Laryngeal mask self-ventilation ; Trachea intubation ; Breast cancer ;
Publication Year: 2010
Publication Date: 2010-12-10
Language: en
Type: article
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