Title: Application of transrectal contrast-enhanced ultrasound in diagnosis of different types of prostatic cancers
Abstract: Objective To investigate the value of transrectal contrast-enhanced ultrasound in diagnosis and clinical staging of different types of prostate cancers. Methods Sixty-six patients with prostate cancer underwent transrectal contrast-enhanced ultrasound with a blot injection of SonoVue. Enhancement patterns of lesions were observed and comparative analysis of contrast parameters of lesions and surrounding tissues were performed off-line by dedicated QLAB software. All cases were examined by ultrasound-guided biopsy. Clinical staging was determined by comparing and analyzing contrast-enhancement patterns and pathological results. Results Twenty-seven cases were classified as diffuse infiltrative type, 16 cases of unilateral type, and 23 cases of focal nodules type, according to the characteristics of two-dimensional ultrasound. The enhancement pattern of diffuse infiltrative type was contrast signal in fast out without well-distribution. Disordered enhancement in the lesions and fast elimination was observed in unilateral type. Focal nodules type showed high-density enhancement with signal fast in and fast out. Conclusions Transrectal contrast-enhanced ultrasound has a significant clinical value for the differential diagnosis of prostatic carcinoid and malignancy, assessment of the lesion range and determining clinical staging of the prostatic lesions.
Key words:
Endosonography; Microbubbles; Prostatic neoplasms
Publication Year: 2009
Publication Date: 2009-08-25
Language: en
Type: article
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