Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W3025724153', 'doi': 'https://doi.org/10.1088/1361-6560/ab936f', 'title': 'TriB-RT: Simultaneous optimization of photon, electron and proton beams', 'display_name': 'TriB-RT: Simultaneous optimization of photon, electron and proton beams', 'publication_year': 2020, 'publication_date': '2020-05-15', 'ids': {'openalex': 'https://openalex.org/W3025724153', 'doi': 'https://doi.org/10.1088/1361-6560/ab936f', 'mag': '3025724153', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/32413883'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1088/1361-6560/ab936f', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S20241394', 'display_name': 'Physics in Medicine and Biology', 'issn_l': '0031-9155', 'issn': ['0031-9155', '1361-6560'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320083', 'host_organization_name': 'IOP Publishing', 'host_organization_lineage': ['https://openalex.org/P4310311669', 'https://openalex.org/P4310320083'], 'host_organization_lineage_names': ['Institute of Physics', 'IOP Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://boris.unibe.ch/144291/1/Kueng%2Bet%2Bal_2020_Phys._Med._Biol._10.1088_1361-6560_ab936f.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5032545256', 'display_name': 'R. Kueng', 'orcid': 'https://orcid.org/0000-0003-3286-640X'}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'R Kueng', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004906997', 'display_name': 'Silvan Mueller', 'orcid': 'https://orcid.org/0000-0002-9835-4362'}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'S Mueller', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026861345', 'display_name': 'Hannes A. Loebner', 'orcid': 'https://orcid.org/0000-0002-8439-2464'}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'H A Loebner', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017317466', 'display_name': 'D Frei', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'D Frei', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073892551', 'display_name': 'W. Volken', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'W Volken', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066416236', 'display_name': 'DM Aebersold', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'D M Aebersold', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002647826', 'display_name': 'Marco Stampanoni', 'orcid': 'https://orcid.org/0000-0001-7486-6681'}, 'institutions': [{'id': 'https://openalex.org/I4210090941', 'display_name': 'Institute for Biomedical Engineering', 'ror': 'https://ror.org/00baskk38', 'country_code': 'CH', 'type': 'facility', 'lineage': ['https://openalex.org/I202697423', 'https://openalex.org/I2799323385', 'https://openalex.org/I35440088', 'https://openalex.org/I4210090941']}, {'id': 'https://openalex.org/I202697423', 'display_name': 'University of Zurich', 'ror': 'https://ror.org/02crff812', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I202697423']}, {'id': 'https://openalex.org/I35440088', 'display_name': 'ETH Zurich', 'ror': 'https://ror.org/05a28rw58', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I2799323385', 'https://openalex.org/I35440088']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'M F M Stampanoni', 'raw_affiliation_strings': ['Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology (ETH), Zurich, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology (ETH), Zurich, Switzerland.', 'institution_ids': ['https://openalex.org/I4210090941', 'https://openalex.org/I202697423', 'https://openalex.org/I35440088']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019068896', 'display_name': 'M.K. Fix', 'orcid': 'https://orcid.org/0000-0002-3911-3403'}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'M K Fix', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5033862514', 'display_name': 'Peter Manser', 'orcid': 'https://orcid.org/0000-0003-3225-8025'}, 'institutions': [{'id': 'https://openalex.org/I2801112126', 'display_name': 'University Hospital of Bern', 'ror': 'https://ror.org/01q9sj412', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801112126']}, {'id': 'https://openalex.org/I118564535', 'display_name': 'University of Bern', 'ror': 'https://ror.org/02k7v4d05', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I118564535']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'P Manser', 'raw_affiliation_strings': ['Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.', 'institution_ids': ['https://openalex.org/I2801112126', 'https://openalex.org/I118564535']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.967, 'has_fulltext': False, 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.999747, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '66', 'issue': '4', 'first_page': '045006', 'last_page': '045006'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10358', 'display_name': 'Advanced Radiotherapy Techniques', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/3108', 'display_name': 'Radiation'}, 'field': {'id': 'https://openalex.org/fields/31', 'display_name': 'Physics and Astronomy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10358', 'display_name': 'Advanced Radiotherapy Techniques', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/3108', 'display_name': 'Radiation'}, 'field': {'id': 'https://openalex.org/fields/31', 'display_name': 'Physics and Astronomy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11176', 'display_name': 'Radiation Therapy and Dosimetry', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11216', 'display_name': 'Radiation Detection and Scintillator Technologies', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/3108', 'display_name': 'Radiation'}, 'field': {'id': 'https://openalex.org/fields/31', 'display_name': 'Physics and Astronomy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2779244869', 'wikidata': 'https://www.wikidata.org/wiki/Q507667', 'display_name': 'Proton therapy', 'level': 3, 'score': 0.8888492}, {'id': 'https://openalex.org/C54516573', 'wikidata': 'https://www.wikidata.org/wiki/Q2294', 'display_name': 'Proton', 'level': 2, 'score': 0.82400864}, {'id': 'https://openalex.org/C159317903', 'wikidata': 'https://www.wikidata.org/wiki/Q3198', 'display_name': 'Photon', 'level': 2, 'score': 0.56640124}, {'id': 'https://openalex.org/C201645570', 'wikidata': 'https://www.wikidata.org/wiki/Q830637', 'display_name': 'Radiation treatment planning', 'level': 3, 'score': 0.5396232}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.53073937}, {'id': 'https://openalex.org/C147120987', 'wikidata': 'https://www.wikidata.org/wiki/Q2225', 'display_name': 'Electron', 'level': 2, 'score': 0.48851}, {'id': 'https://openalex.org/C75088862', 'wikidata': 'https://www.wikidata.org/wiki/Q2291081', 'display_name': 'Dosimetry', 'level': 2, 'score': 0.46765536}, {'id': 'https://openalex.org/C2989005', 'wikidata': 'https://www.wikidata.org/wiki/Q214963', 'display_name': 'Nuclear medicine', 'level': 1, 'score': 0.45937052}, {'id': 'https://openalex.org/C168834538', 'wikidata': 'https://www.wikidata.org/wiki/Q3705329', 'display_name': 'Beam (structure)', 'level': 2, 'score': 0.4579678}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.43979505}, {'id': 'https://openalex.org/C19527891', 'wikidata': 'https://www.wikidata.org/wiki/Q1120908', 'display_name': 'Medical physics', 'level': 1, 'score': 0.40530735}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.39195675}, {'id': 'https://openalex.org/C185544564', 'wikidata': 'https://www.wikidata.org/wiki/Q81197', 'display_name': 'Nuclear physics', 'level': 1, 'score': 0.26421636}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.25461686}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.21696788}, {'id': 'https://openalex.org/C126838900', 'wikidata': 'https://www.wikidata.org/wiki/Q77604', 'display_name': 'Radiology', 'level': 1, 'score': 0.080239415}], 'mesh': [{'descriptor_ui': 'D004583', 'descriptor_name': 'Electrons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006258', 'descriptor_name': 'Head and Neck Neoplasms', 'qualifier_ui': 'Q000532', 'qualifier_name': 'radiotherapy', 'is_major_topic': True}, {'descriptor_ui': 'D010386', 'descriptor_name': 'Pelvic Neoplasms', 'qualifier_ui': 'Q000532', 'qualifier_name': 'radiotherapy', 'is_major_topic': True}, {'descriptor_ui': 'D019047', 'descriptor_name': 'Phantoms, Imaging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D017785', 'descriptor_name': 'Photons', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D061766', 'descriptor_name': 'Proton Therapy', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': True}, {'descriptor_ui': 'D011880', 'descriptor_name': 'Radiotherapy Planning, Computer-Assisted', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': True}, {'descriptor_ui': 'D006258', 'descriptor_name': 'Head and Neck Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009010', 'descriptor_name': 'Monte Carlo Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010386', 'descriptor_name': 'Pelvic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017785', 'descriptor_name': 'Photons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061766', 'descriptor_name': 'Proton Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061766', 'descriptor_name': 'Proton Therapy', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D011874', 'descriptor_name': 'Radiometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011879', 'descriptor_name': 'Radiotherapy Dosage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011880', 'descriptor_name': 'Radiotherapy Planning, Computer-Assisted', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011880', 'descriptor_name': 'Radiotherapy Planning, Computer-Assisted', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D050397', 'descriptor_name': 'Radiotherapy, Intensity-Modulated', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': False}, {'descriptor_ui': 'D050397', 'descriptor_name': 'Radiotherapy, Intensity-Modulated', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1088/1361-6560/ab936f', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S20241394', 'display_name': 'Physics in Medicine and Biology', 'issn_l': '0031-9155', 'issn': ['0031-9155', '1361-6560'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320083', 'host_organization_name': 'IOP Publishing', 'host_organization_lineage': ['https://openalex.org/P4310311669', 'https://openalex.org/P4310320083'], 'host_organization_lineage_names': ['Institute of Physics', 'IOP Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://boris.unibe.ch/144291/', 'pdf_url': 'https://boris.unibe.ch/144291/1/Kueng%2Bet%2Bal_2020_Phys._Med._Biol._10.1088_1361-6560_ab936f.pdf', 'source': {'id': 'https://openalex.org/S4306401086', 'display_name': 'Bern Open Repository and Information System (University of Bern)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I118564535', 'host_organization_name': 'University of Bern', 'host_organization_lineage': ['https://openalex.org/I118564535'], 'host_organization_lineage_names': ['University of Bern'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/32413883', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://boris.unibe.ch/144291/', 'pdf_url': 'https://boris.unibe.ch/144291/1/Kueng%2Bet%2Bal_2020_Phys._Med._Biol._10.1088_1361-6560_ab936f.pdf', 'source': {'id': 'https://openalex.org/S4306401086', 'display_name': 'Bern Open Repository and Information System (University of Bern)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I118564535', 'host_organization_name': 'University of Bern', 'host_organization_lineage': ['https://openalex.org/I118564535'], 'host_organization_lineage_names': ['University of Bern'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.67, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320309603', 'funder_display_name': 'Varian Medical Systems', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 40, 'referenced_works': ['https://openalex.org/W1964769757', 'https://openalex.org/W1967510893', 'https://openalex.org/W1972020572', 'https://openalex.org/W1975598755', 'https://openalex.org/W1978217978', 'https://openalex.org/W1979788158', 'https://openalex.org/W1983273276', 'https://openalex.org/W1983869432', 'https://openalex.org/W1984135262', 'https://openalex.org/W1992393117', 'https://openalex.org/W1995493340', 'https://openalex.org/W2017544853', 'https://openalex.org/W2019850432', 'https://openalex.org/W2021482893', 'https://openalex.org/W2022295520', 'https://openalex.org/W2029728138', 'https://openalex.org/W2043582502', 'https://openalex.org/W2049181072', 'https://openalex.org/W2055649358', 'https://openalex.org/W2056641273', 'https://openalex.org/W2063587223', 'https://openalex.org/W2072276987', 'https://openalex.org/W2076663431', 'https://openalex.org/W2084851290', 'https://openalex.org/W2150308478', 'https://openalex.org/W2557556302', 'https://openalex.org/W2606807491', 'https://openalex.org/W2610531088', 'https://openalex.org/W2612496985', 'https://openalex.org/W2686645342', 'https://openalex.org/W2775040859', 'https://openalex.org/W2788438055', 'https://openalex.org/W2795152895', 'https://openalex.org/W2848091815', 'https://openalex.org/W2908811472', 'https://openalex.org/W2972593451', 'https://openalex.org/W2972711982', 'https://openalex.org/W2999223320', 'https://openalex.org/W4245214678', 'https://openalex.org/W92266575'], 'related_works': ['https://openalex.org/W3025724153', 'https://openalex.org/W3011224823', 'https://openalex.org/W2901288344', 'https://openalex.org/W2115968180', 'https://openalex.org/W2089143449', 'https://openalex.org/W2065864741', 'https://openalex.org/W2053144828', 'https://openalex.org/W2050722109', 'https://openalex.org/W2029285485', 'https://openalex.org/W1013145701'], 'abstract_inverted_index': {'Abstract': [0], 'Purpose.': [1], 'To': [2, 102], 'develop': [3], 'a': [4, 72, 107, 126, 132, 241, 265, 304, 310], 'novel': [5, 272], 'treatment': [6, 22, 46, 74, 291], 'planning': [7, 75], 'process': [8], '(TPP)': [9], 'with': [10, 131, 303, 309], 'simultaneous': [11], 'optimization': [12, 33, 156], 'of': [13, 34, 49, 95, 123, 143, 175, 186, 226, 240, 256], 'modulated': [14, 60], 'photon,': [15, 50, 277], 'electron': [16, 51, 278, 316], 'and': [17, 52, 91, 154, 202, 279, 294, 315], 'proton': [18, 55, 61, 68, 128, 134, 152, 243, 268, 280, 301], 'beams': [19, 281], 'for': [20, 30, 86, 117, 125, 160, 165, 289, 298], 'improved': [21, 184, 290], 'plan': [23, 83, 109, 116, 171, 261, 292], 'quality': [24, 149, 262, 293], 'in': [25, 254, 307], 'radiotherapy.': [26], 'Methods.': [27], 'A': [28, 78, 271], 'framework': [29], 'fluence': [31], 'map': [32], 'Monte': [35], 'Carlo': [36], '(MC)': [37], 'calculated': [38], 'beamlet': [39], 'dose': [40, 93, 230], 'distributions': [41], 'is': [42, 84, 110, 195, 295], 'developed': [43], 'to': [44, 67, 112, 191, 198, 250, 258, 264], 'generate': [45], 'plans': [47, 64, 69, 247], 'consisting': [48], 'spot': [53], 'scanning': [54], 'fields.': [56, 317], 'Initially,': [57], 'in-house': [58, 114], 'intensity': [59], 'therapy': [62], '(IMPT)': [63], 'are': [65, 100, 136, 142, 248], 'compared': [66, 111, 197, 263], 'created': [70], 'by': [71], 'commercial': [73], 'system': [76], '(TPS).': [77], 'triple': [79], 'beam': [80, 129, 244], 'radiotherapy': [81], '(TriB-RT)': [82], 'generated': [85], 'an': [87, 113, 227], 'exemplary': [88], 'academic': [89, 167], 'case': [90], 'the': [92, 96, 104, 166, 169, 180, 192, 238, 252, 287], 'contributions': [94], 'three': [97], 'particle': [98, 177], 'types': [99], 'investigated.': [101, 137], 'investigate': [103], 'dosimetric': [105, 158], 'potential,': [106], 'TriB-RT': [108, 124, 246, 285], 'IMPT': [115, 141, 199], 'two': [118], 'clinically': [119, 181], 'motivated': [120, 182], 'cases.': [121], 'Benefits': [122], 'fixed': [127, 242, 305], 'line': [130], 'single': [133, 266], 'field': [135, 267], 'Results.': [138], 'In-house': [139], 'optimized': [140], 'at': [144, 188, 224], 'least': [145], 'equal': [146], 'or': [147], 'better': [148], 'than': [150], 'TPS-generated': [151], 'plans,': [153], 'MC-based': [155], 'shows': [157, 172, 286], 'advantages': [159], 'inhomogeneous': [161], 'situations.': [162], 'Concerning': [163], 'TriB-RT,': [164], 'case,': [168, 183], 'resulting': [170], 'substantial': [173], 'contribution': [174], 'all': [176], 'types.': [178], 'For': [179], 'sparing': [185], 'organs': [187], 'risk': [189], 'close': [190], 'target': [193], 'volume': [194], 'achieved': [196], '(e.g.': [200], 'myelon': [201], 'brainstem': [203], '<?CDATA': [204], '$D_{\\mathrm{max}}$?>': [205], '<mml:math': [206], 'xmlns:mml="http://www.w3.org/1998/Math/MathML"': [207], 'overflow="scroll">': [208], '<mml:msub>': [209], '<mml:mi>D</mml:mi>': [210], '<mml:mrow>': [211, 212], '<mml:mi': [213, 215, 217], 'mathvariant="normal">m</mml:mi>': [214], 'mathvariant="normal">a</mml:mi>': [216], 'mathvariant="normal">x</mml:mi>': [218], '</mml:mrow>': [219, 220], '</mml:msub>': [221], '</mml:math>': [222], '−37%)': [223], 'cost': [225], 'increased': [228], 'low': [229], 'bath': [231], '(healthy': [232], 'tissue': [233], 'V': [234], '10%': [235], '+22%).': [236], 'In': [237], 'scenario': [239], 'line,': [245], 'able': [249], 'compensate': [251], 'loss': [253], 'degrees': [255], 'freedom': [257], 'substantially': [259], 'improve': [260], 'plan.': [269], 'Conclusion.': [270], 'TPP': [273], 'which': [274], 'simultaneously': [275], 'optimizes': [276], 'was': [282], 'successfully': [283], 'developed.': [284], 'potential': [288], 'especially': [296], 'promising': [297], 'cost-effective': [299], 'single-room': [300], 'solutions': [302], 'beamline': [306], 'combination': [308], 'conventional': [311], 'linac': [312], 'delivering': [313], 'photon': [314]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3025724153', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}], 'updated_date': '2024-12-13T09:15:34.527203', 'created_date': '2020-05-21'}