Publication Information

{'id': 'https://openalex.org/W3024312050', 'doi': 'https://doi.org/10.26355/eurrev_201801_14200', 'title': 'Hyperoxia induces the apoptosis of alveolar epithelial cells and changes of pulmonary surfactant proteins.', 'display_name': 'Hyperoxia induces the apoptosis of alveolar epithelial cells and changes of pulmonary surfactant proteins.', 'publication_year': 2018, 'publication_date': '2018-01-01', 'ids': {'openalex': 'https://openalex.org/W3024312050', 'doi': 'https://doi.org/10.26355/eurrev_201801_14200', 'mag': '3024312050', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29424908'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29424908', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100770475', 'display_name': 'Jin Yao', 'orcid': 'https://orcid.org/0000-0003-3028-9370'}, 'institutions': [{'id': 'https://openalex.org/I111381250', 'display_name': 'Hebei Medical University', 'ror': 'https://ror.org/04eymdx19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I111381250']}, {'id': 'https://openalex.org/I4210115020', 'display_name': "Xingtai People's Hospital", 'ror': 'https://ror.org/0284jzx23', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210115020']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jin Y', 'raw_affiliation_strings': ["Department of Pediatrics, Xingtai People's Hospital, Xingtai, Hebei Province, China. [email protected]."], 'affiliations': [{'raw_affiliation_string': "Department of Pediatrics, Xingtai People's Hospital, Xingtai, Hebei Province, China. [email protected].", 'institution_ids': ['https://openalex.org/I111381250', 'https://openalex.org/I4210115020']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028035063', 'display_name': 'Peng Lq', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Peng Lq', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5039183958', 'display_name': 'Zhao Al', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Zhao Al', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1800, 'currency': 'EUR', 'value_usd': 1964, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.208, 'has_fulltext': False, 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.890108, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '22', 'issue': '2', 'first_page': '492', 'last_page': '497'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10549', 'display_name': 'Neonatal Respiratory Health Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10549', 'display_name': 'Neonatal Respiratory Health Research', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10322', 'display_name': 'Respiratory Support and Mechanisms', 'score': 0.9644, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11586', 'display_name': 'Congenital Diaphragmatic Hernia Studies', 'score': 0.9481, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hyperoxia', 'display_name': 'Hyperoxia', 'score': 0.9562997}, {'id': 'https://openalex.org/keywords/surfactant-protein-c', 'display_name': 'Surfactant protein C', 'score': 0.7276199}, {'id': 'https://openalex.org/keywords/room-air-distribution', 'display_name': 'Room air distribution', 'score': 0.44694376}], 'concepts': [{'id': 'https://openalex.org/C2780672939', 'wikidata': 'https://www.wikidata.org/wiki/Q5958429', 'display_name': 'Hyperoxia', 'level': 3, 'score': 0.9562997}, {'id': 'https://openalex.org/C196795494', 'wikidata': 'https://www.wikidata.org/wiki/Q1624817', 'display_name': 'TUNEL assay', 'level': 3, 'score': 0.7288527}, {'id': 'https://openalex.org/C2778729956', 'wikidata': 'https://www.wikidata.org/wiki/Q7646058', 'display_name': 'Surfactant protein C', 'level': 3, 'score': 0.7276199}, {'id': 'https://openalex.org/C2777961210', 'wikidata': 'https://www.wikidata.org/wiki/Q927148', 'display_name': 'Bronchoalveolar lavage', 'level': 3, 'score': 0.68829066}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.67556375}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.6693315}, {'id': 'https://openalex.org/C58226133', 'wikidata': 'https://www.wikidata.org/wiki/Q1324199', 'display_name': 'Pulmonary surfactant', 'level': 2, 'score': 0.6405434}, {'id': 'https://openalex.org/C125473707', 'wikidata': 'https://www.wikidata.org/wiki/Q9914', 'display_name': 'H&E stain', 'level': 3, 'score': 0.54334223}, {'id': 'https://openalex.org/C16685009', 'wikidata': 'https://www.wikidata.org/wiki/Q335057', 'display_name': 'Andrology', 'level': 1, 'score': 0.5411955}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.49370632}, {'id': 'https://openalex.org/C20564796', 'wikidata': 'https://www.wikidata.org/wiki/Q1428108', 'display_name': 'Room air distribution', 'level': 2, 'score': 0.44694376}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.43676305}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34868866}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.33025074}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3251896}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.2918115}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.28244102}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2781262}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.11292431}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C97355855', 'wikidata': 'https://www.wikidata.org/wiki/Q11473', 'display_name': 'Thermodynamics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D037663', 'descriptor_name': 'Pulmonary Surfactant-Associated Protein D', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D056809', 'descriptor_name': 'Alveolar Epithelial Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056809', 'descriptor_name': 'Alveolar Epithelial Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D056809', 'descriptor_name': 'Alveolar Epithelial Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000831', 'descriptor_name': 'Animals, Newborn', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001992', 'descriptor_name': 'Bronchoalveolar Lavage Fluid', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D001992', 'descriptor_name': 'Bronchoalveolar Lavage Fluid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D037663', 'descriptor_name': 'Pulmonary Surfactant-Associated Protein D', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29424908', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/14', 'display_name': 'Life below water', 'score': 0.52}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3024312050', 'https://openalex.org/W2432240004', 'https://openalex.org/W2370428237', 'https://openalex.org/W2347544801', 'https://openalex.org/W2142919707', 'https://openalex.org/W2131344464', 'https://openalex.org/W2055009227', 'https://openalex.org/W1984685339', 'https://openalex.org/W1860714010', 'https://openalex.org/W1637390070'], 'abstract_inverted_index': {'To': [0], 'explore': [1], 'the': [2, 19, 38, 45, 53, 75, 128, 143, 146, 159, 185, 189, 192, 197, 203, 208, 216, 220, 225, 229, 232, 240, 247, 255, 263, 266, 271, 279, 287, 294, 302, 308, 315, 327, 333, 342], 'changes': [3, 107], 'of': [4, 13, 22, 71, 87, 108, 115, 130, 161, 194, 205, 252, 268, 317, 321, 329, 344], 'surfactant': [5], 'protein': [6], 'C,': [7], 'D': [8], '(SP-C,': [9], 'SP-D)': [10], 'and': [11, 44, 56, 62, 68, 80, 95, 99, 104, 111, 153, 165, 171, 180, 235, 243, 297, 326, 338], 'apoptosis': [12, 113, 320], 'alveolar': [14, 116, 147, 162, 322], 'epithelial': [15, 117, 323], 'cells': [16, 118, 179, 324], '(AEC)': [17], 'in': [18, 52, 63, 90, 133, 184, 196, 207, 215, 254, 270, 278, 332], 'lung': [20, 85, 109, 182, 334], 'injury': [21], 'neonatal': [23, 29], 'rats': [24, 30, 89], 'induced': [25], 'by': [26, 119, 138], 'hyperoxia.We': [27], 'divided': [28], 'within': [31], '24': [32], 'hours': [33], 'into': [34], 'two': [35], 'groups': [36], 'randomly:': [37], 'air': [39, 54, 144, 190, 217, 256, 280], 'group': [40, 47, 55, 58, 92, 210, 218, 257, 273], '(n': [41, 48], '=': [42, 49], '50)': [43], 'hyperoxia': [46, 57, 186, 209, 272, 313], '50).': [50], 'Rats': [51], 'were': [59], 'bred': [60], 'conventionally': [61], 'tanks': [64], 'with': [65, 97, 150, 260, 341], 'normal': [66], 'pressure': [67], '90%': [69], 'concentration': [70], 'oxygen,': [72], 'respectively.': [73], 'On': [74, 262], '1st,': [76], '3rd,': [77], '7th,': [78], '10th,': [79], '14th': [81], 'day': [82, 234, 242], 'after': [83], 'exposure,': [84], 'tissue': [86, 110, 183, 335], '8': [88], 'each': [91], 'was': [93, 211, 274], 'collected': [94], 'stained': [96], 'hematoxylin': [98], 'eosin': [100], '(HE).': [101], 'We': [102, 126], 'observed': [103, 167], 'recorded': [105], 'pathologic': [106], 'detected': [112, 127], 'rate': [114], 'TUNEL': [120], '(TdT-mediated': [121], 'dUTP': [122], 'nick': [123], 'end': [124], 'labeling).': [125], 'content': [129, 193, 204, 267, 328], 'SP-C,': [131, 330], 'SP-D': [132, 253, 269, 331], 'bronchoalveolar': [134], 'lavage': [135], 'fluid': [136], '(BALF)': [137], 'ELISA': [139], '(enzyme-linked': [140], 'immunosorbent': [141], 'assay).In': [142], 'group,': [145, 191], 'formed': [148], 'gradually': [149, 164, 259], 'equable': [151], 'size': [152], 'regular': [154], 'shape': [155], 'during': [156, 200], 'growth.': [157, 201], 'While': [158], 'amount': [160], 'decreased': [163, 340], 'we': [166], 'small': [168], 'vessels': [169], 'dilation': [170], 'increasing': [172, 177], 'hemorrhage': [173], 'as': [174, 176], 'well': [175], 'interstitial': [178], 'swollen': [181], 'group.': [187, 281], 'In': [188], 'SP-C': [195, 206], 'BALF': [198], 'reduced': [199], 'However,': [202], 'lower': [212], 'than': [213], 'that': [214, 277], 'on': [219, 224, 231, 239, 246, 286, 293, 301, 307], 'first': [221, 264, 336], 'day,': [222, 227, 265, 289, 296, 304], 'higher': [223], 'third': [226, 288], 'reached': [228, 290], 'peak': [230, 292], 'seventh': [233, 295], 'began': [236, 283, 298], 'to': [237, 276, 284, 299, 312], 'decrease': [238, 300], 'tenth': [241, 303], 'more': [244, 305], 'obviously': [245, 306], 'fourteenth': [248, 309], 'day.': [249], 'The': [250, 319], 'level': [251], 'declined': [258], 'growing.': [261], 'similar': [275], 'It': [282], 'increase': [285, 343], 'its': [291], 'day.Long-term': [310], 'exposure': [311, 345], 'inhibits': [314], 'development': [316], 'alveolar.': [318], 'increased': [325, 337], 'then': [339], 'time.': [346]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3024312050', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 8}], 'updated_date': '2024-12-11T20:23:31.081305', 'created_date': '2020-05-21'}