Abstract: The stomach is a powerful secretory organ lined by mucosa of about 1 mm thickness that lies over muscularis mucosae, which is responsible for much of the motor power behind gastric emptying. The superficial cells from cardia to pylorus all look alike microscopically and are damaged equally by the same chemical or physical agents. The turnover of these cells is high and they secrete mucous glycoproteins. In the antrum are found two types of cell that are present in only small numbers elsewhere in the stomach: (1) argentaffin or enterochromaffin cells (the EC cells) and (2) gastrin-producing cells (the G cells). The surface reaction in the antrum is neutral to alkaline and a sharp pH border can be demonstrated between antrum and the body of the stomach. When the mucosa of the fundus and corpus is damaged, H+ ions fail to be secreted and appear to be replaced by Na ions. The result is an alkaline surface reaction. The mucosa receives a generous supply of blood and lymph and comes under the strong nervous impulses of sympathetic and parasympathetic origin, transmitted via a rich submucosal plexus.
Publication Year: 1981
Publication Date: 1981-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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