Publication Information

{'id': 'https://openalex.org/W3015719748', 'doi': 'https://doi.org/10.1117/12.2559929', 'title': 'Study of the effect of a proteasome inhibitor on actin cytoskeleton remodeling in the nerve cells by fluorescence imaging', 'display_name': 'Study of the effect of a proteasome inhibitor on actin cytoskeleton remodeling in the nerve cells by fluorescence imaging', 'publication_year': 2020, 'publication_date': '2020-04-09', 'ids': {'openalex': 'https://openalex.org/W3015719748', 'doi': 'https://doi.org/10.1117/12.2559929', 'mag': '3015719748'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1117/12.2559929', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'proceedings-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5060047760', 'display_name': 'Natalia S. Maximova', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I100051649', 'display_name': 'Privolzhsky Research Medical University', 'ror': 'https://ror.org/00apdsa62', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I100051649']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'Natalia S. Maximova', 'raw_affiliation_strings': ['Privolzhsky Research Medical Univ. (Russian Federation)'], 'affiliations': [{'raw_affiliation_string': 'Privolzhsky Research Medical Univ. (Russian Federation)', 'institution_ids': ['https://openalex.org/I100051649']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108719334', 'display_name': 'V.I. Pershin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I100051649', 'display_name': 'Privolzhsky Research Medical University', 'ror': 'https://ror.org/00apdsa62', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I100051649']}, {'id': 'https://openalex.org/I79563041', 'display_name': 'N. I. Lobachevsky State University of Nizhny Novgorod', 'ror': 'https://ror.org/01bb1zm18', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I79563041']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'Vladimir I. Pershin', 'raw_affiliation_strings': ['Lobachevsky State Univ. of Nizhny Novgorod (Russian Federation)', 'Privolzhsky Research Medical Univ. (Russian Federation)'], 'affiliations': [{'raw_affiliation_string': 'Privolzhsky Research Medical Univ. (Russian Federation)', 'institution_ids': ['https://openalex.org/I100051649']}, {'raw_affiliation_string': 'Lobachevsky State Univ. of Nizhny Novgorod (Russian Federation)', 'institution_ids': ['https://openalex.org/I79563041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088786230', 'display_name': 'Н М Ткаченко', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I100051649', 'display_name': 'Privolzhsky Research Medical University', 'ror': 'https://ror.org/00apdsa62', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I100051649']}, {'id': 'https://openalex.org/I79563041', 'display_name': 'N. I. Lobachevsky State University of Nizhny Novgorod', 'ror': 'https://ror.org/01bb1zm18', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I79563041']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'Natalia M. Tkachenko', 'raw_affiliation_strings': ['Lobachevsky State Univ. of Nizhny Novgorod (Russian Federation)', 'Privolzhsky Research Medical Univ. (Russian Federation)'], 'affiliations': [{'raw_affiliation_string': 'Privolzhsky Research Medical Univ. (Russian Federation)', 'institution_ids': ['https://openalex.org/I100051649']}, {'raw_affiliation_string': 'Lobachevsky State Univ. of Nizhny Novgorod (Russian Federation)', 'institution_ids': ['https://openalex.org/I79563041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088945447', 'display_name': 'Murat Gainullin', 'orcid': 'https://orcid.org/0000-0002-3433-2279'}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Murat  . Gainullin', 'raw_affiliation_strings': ['Oslo Univ. Hospital (Norway)'], 'affiliations': [{'raw_affiliation_string': 'Oslo Univ. Hospital (Norway)', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084931025', 'display_name': 'И.В. Мухина', 'orcid': 'https://orcid.org/0000-0002-8811-0049'}, 'institutions': [{'id': 'https://openalex.org/I79563041', 'display_name': 'N. I. Lobachevsky State University of Nizhny Novgorod', 'ror': 'https://ror.org/01bb1zm18', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I79563041']}, {'id': 'https://openalex.org/I100051649', 'display_name': 'Privolzhsky Research Medical University', 'ror': 'https://ror.org/00apdsa62', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I100051649']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'Irina V. Mukhina', 'raw_affiliation_strings': ['Lobachevsky State Univ. of Nizhny Novgorod (Russian Federation)', 'Privolzhsky Research Medical Univ. (Russian Federation)'], 'affiliations': [{'raw_affiliation_string': 'Lobachevsky State Univ. of Nizhny Novgorod (Russian Federation)', 'institution_ids': ['https://openalex.org/I79563041']}, {'raw_affiliation_string': 'Privolzhsky Research Medical Univ. (Russian Federation)', 'institution_ids': ['https://openalex.org/I100051649']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5037808855', 'display_name': 'Tatiana F. Kovaleva', 'orcid': 'https://orcid.org/0000-0002-3440-704X'}, 'institutions': [{'id': 'https://openalex.org/I100051649', 'display_name': 'Privolzhsky Research Medical University', 'ror': 'https://ror.org/00apdsa62', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I100051649']}], 'countries': ['RU'], 'is_corresponding': False, 'raw_author_name': 'Tatiana F. Kovaleva', 'raw_affiliation_strings': ['Privolzhsky Research Medical Univ. (Russian Federation)'], 'affiliations': [{'raw_affiliation_string': 'Privolzhsky Research Medical Univ. (Russian Federation)', 'institution_ids': ['https://openalex.org/I100051649']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 60}, 'biblio': {'volume': None, 'issue': None, 'first_page': '10', 'last_page': '10'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin and proteasome pathways', 'score': 0.9201, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin and proteasome pathways', 'score': 0.9201, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cofilin', 'display_name': 'Cofilin', 'score': 0.90981907}, {'id': 'https://openalex.org/keywords/actin-remodeling', 'display_name': 'Actin remodeling', 'score': 0.8061037}, {'id': 'https://openalex.org/keywords/mg132', 'display_name': 'MG132', 'score': 0.70686054}, {'id': 'https://openalex.org/keywords/mdia1', 'display_name': 'MDia1', 'score': 0.47438958}, {'id': 'https://openalex.org/keywords/actin-binding-protein', 'display_name': 'Actin-binding protein', 'score': 0.4232443}], 'concepts': [{'id': 'https://openalex.org/C2776601116', 'wikidata': 'https://www.wikidata.org/wiki/Q24786722', 'display_name': 'Cofilin', 'level': 5, 'score': 0.90981907}, {'id': 'https://openalex.org/C3620293', 'wikidata': 'https://www.wikidata.org/wiki/Q14908027', 'display_name': 'Actin remodeling', 'level': 5, 'score': 0.8061037}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.79737425}, {'id': 'https://openalex.org/C151000934', 'wikidata': 'https://www.wikidata.org/wiki/Q4676834', 'display_name': 'Actin remodeling of neurons', 'level': 5, 'score': 0.7175108}, {'id': 'https://openalex.org/C2778506107', 'wikidata': 'https://www.wikidata.org/wiki/Q3272916', 'display_name': 'MG132', 'level': 4, 'score': 0.70686054}, {'id': 'https://openalex.org/C2993400109', 'wikidata': 'https://www.wikidata.org/wiki/Q329638', 'display_name': 'Actin cytoskeleton', 'level': 4, 'score': 0.6217461}, {'id': 'https://openalex.org/C142669718', 'wikidata': 'https://www.wikidata.org/wiki/Q154626', 'display_name': 'Cytoskeleton', 'level': 3, 'score': 0.602734}, {'id': 'https://openalex.org/C125705527', 'wikidata': 'https://www.wikidata.org/wiki/Q185269', 'display_name': 'Actin', 'level': 2, 'score': 0.5185126}, {'id': 'https://openalex.org/C59999672', 'wikidata': 'https://www.wikidata.org/wiki/Q21497084', 'display_name': 'MDia1', 'level': 5, 'score': 0.47438958}, {'id': 'https://openalex.org/C130861313', 'wikidata': 'https://www.wikidata.org/wiki/Q3775363', 'display_name': 'Actin-binding protein', 'level': 5, 'score': 0.4232443}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4115115}, {'id': 'https://openalex.org/C27740335', 'wikidata': 'https://www.wikidata.org/wiki/Q14878333', 'display_name': 'Proteasome', 'level': 2, 'score': 0.36180133}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.35686767}, {'id': 'https://openalex.org/C2778367456', 'wikidata': 'https://www.wikidata.org/wiki/Q7251235', 'display_name': 'Proteasome inhibitor', 'level': 3, 'score': 0.30388007}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.18733904}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.11619297}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1117/12.2559929', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2755233762', 'https://openalex.org/W2472516939', 'https://openalex.org/W2106334412', 'https://openalex.org/W2100455753', 'https://openalex.org/W2084958568', 'https://openalex.org/W2083590644', 'https://openalex.org/W2080945459', 'https://openalex.org/W2011545163', 'https://openalex.org/W1983813017', 'https://openalex.org/W113641295'], 'abstract_inverted_index': {'The': [0, 94, 148], 'ubiquitin-proteasome': [1], 'system': [2, 48, 206], 'is': [3, 35, 73], 'a': [4, 21, 36, 105], 'major': [5], 'protein': [6], 'degradative': [7], 'pathway': [8], 'involved': [9], 'in': [10, 24, 59, 69, 113, 131, 159, 185], 'the': [11, 25, 31, 46, 55, 60, 70, 84, 102, 114, 139, 157, 160, 173, 176, 186, 194, 204], 'maintenance': [12], 'of': [13, 30, 39, 45, 57, 62, 90, 96, 104, 135, 141, 150, 162, 166, 170, 196, 199, 203], 'cellular': [14], 'structure': [15, 68, 161], 'and': [16, 27, 65, 87, 129, 168, 181, 201], 'function.': [17], 'Actin': [18], 'cytoskeleton': [19, 67, 92, 111, 183], 'plays': [20], 'critical': [22], 'role': [23, 56], 'morphology': [26], 'structural': [28], 'changes': [29, 158], 'nerve': [32, 47, 71, 115, 187, 205], 'cells.': [33, 133, 188], 'Cofilin': [34, 120], 'main': [37], 'regulator': [38], 'actin': [40, 66, 91, 110, 127, 163, 182], 'filament': [41], 'assembly/disassembly.': [42], 'Many': [43], 'diseases': [44], 'are': [49, 80], 'associated': [50], 'with': [51, 126, 153], 'actin-cofilin': [52], 'remodeling.': [53], 'Nevertheless,': [54], 'ubiquitylation': [58, 180], 'regulation': [61], 'cofilin': [63, 136, 142, 179], 'activity': [64], 'cells': [72, 116, 152], 'little': [74], 'investigated.': [75], 'Confocal': [76], 'fluorescence': [77, 118], 'microscopy-based': [78], 'methods': [79, 198], 'valuable': [81], 'tools': [82], 'for': [83, 193], 'precise': [85], 'imaging': [86], 'quantitative': [88], 'evaluation': [89], 'changes.': [93], 'aim': [95], 'this': [97], 'research': [98], 'was': [99, 121], 'to': [100, 123, 156], 'analyze': [101], 'effect': [103], 'proteasome': [106], 'inhibitor': [107], 'MG132': [108, 154], 'on': [109], 'remodeling': [112, 184], 'using': [117], 'imaging.': [119], 'shown': [122], 'be': [124, 191], 'colocalized': [125], 'filaments': [128], 'ubiquitin': [130], 'hippocampal': [132, 151], 'Analysis': [134], 'proteoforms': [137], 'revealed': [138], 'presence': [140], 'modified': [143], 'by': [144], 'K63-linked': [145], 'multiubiquitin': [146], 'chains.': [147], 'treatment': [149, 202], 'led': [155], 'cytoskeleton,': [164], 'expression': [165], 'cofilin,': [167], 'activation': [169], 'autophagy.': [171], 'Therefore,': [172], 'results': [174], 'suggest': [175], 'relationship': [177], 'between': [178], 'It': [189], 'may': [190], 'important': [192], 'development': [195], 'new': [197], 'diagnosis': [200], 'disorders.': [207]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3015719748', 'counts_by_year': [], 'updated_date': '2025-01-08T13:02:09.567845', 'created_date': '2020-04-17'}