Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2080945459', 'doi': 'https://doi.org/10.1083/jcb.145.6.1251', 'title': 'Aip1p Interacts with Cofilin to Disassemble Actin Filaments', 'display_name': 'Aip1p Interacts with Cofilin to Disassemble Actin Filaments', 'publication_year': 1999, 'publication_date': '1999-06-14', 'ids': {'openalex': 'https://openalex.org/W2080945459', 'doi': 'https://doi.org/10.1083/jcb.145.6.1251', 'mag': '2080945459', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10366597', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2133144'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.145.6.1251', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1083/jcb.145.6.1251', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5070846414', 'display_name': 'Avital A. Rodal', 'orcid': 'https://orcid.org/0000-0002-2051-8304'}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I133731052', 'display_name': 'University of Helsinki', 'ror': 'https://ror.org/040af2s02', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I133731052']}, {'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}, {'id': 'https://openalex.org/I2800229700', 'display_name': 'Helsinki Institute of Physics', 'ror': 'https://ror.org/01x2x1522', 'country_code': 'FI', 'type': 'facility', 'lineage': ['https://openalex.org/I133731052', 'https://openalex.org/I2800229700', 'https://openalex.org/I63548447', 'https://openalex.org/I94722563', 'https://openalex.org/I9927081']}], 'countries': ['FI', 'US'], 'is_corresponding': False, 'raw_author_name': 'Avital A. Rodal', 'raw_affiliation_strings': ['*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'Institute of Biotechnology, 00014 University of Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': '*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I1327163397', 'https://openalex.org/I133731052']}, {'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'institution_ids': ['https://openalex.org/I95457486']}, {'raw_affiliation_string': 'Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2800229700', 'https://openalex.org/I133731052']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043802114', 'display_name': 'Jonathan W. Tetreault', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}, {'id': 'https://openalex.org/I133731052', 'display_name': 'University of Helsinki', 'ror': 'https://ror.org/040af2s02', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I133731052']}, {'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I2800229700', 'display_name': 'Helsinki Institute of Physics', 'ror': 'https://ror.org/01x2x1522', 'country_code': 'FI', 'type': 'facility', 'lineage': ['https://openalex.org/I133731052', 'https://openalex.org/I2800229700', 'https://openalex.org/I63548447', 'https://openalex.org/I94722563', 'https://openalex.org/I9927081']}], 'countries': ['FI', 'US'], 'is_corresponding': False, 'raw_author_name': 'Jonathan W. Tetreault', 'raw_affiliation_strings': ['*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'Institute of Biotechnology, 00014 University of Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'institution_ids': ['https://openalex.org/I95457486']}, {'raw_affiliation_string': '*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I133731052', 'https://openalex.org/I1327163397']}, {'raw_affiliation_string': 'Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2800229700', 'https://openalex.org/I133731052']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013579145', 'display_name': 'Pekka Lappalainen', 'orcid': 'https://orcid.org/0000-0001-6227-0354'}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}, {'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I133731052', 'display_name': 'University of Helsinki', 'ror': 'https://ror.org/040af2s02', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I133731052']}, {'id': 'https://openalex.org/I2800229700', 'display_name': 'Helsinki Institute of Physics', 'ror': 'https://ror.org/01x2x1522', 'country_code': 'FI', 'type': 'facility', 'lineage': ['https://openalex.org/I133731052', 'https://openalex.org/I2800229700', 'https://openalex.org/I63548447', 'https://openalex.org/I94722563', 'https://openalex.org/I9927081']}], 'countries': ['FI', 'US'], 'is_corresponding': False, 'raw_author_name': 'Pekka Lappalainen', 'raw_affiliation_strings': ['*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'Institute of Biotechnology, 00014 University of Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'institution_ids': ['https://openalex.org/I95457486']}, {'raw_affiliation_string': '*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I1327163397', 'https://openalex.org/I133731052']}, {'raw_affiliation_string': 'Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2800229700', 'https://openalex.org/I133731052']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061998778', 'display_name': 'David G. Drubin', 'orcid': 'https://orcid.org/0000-0003-3002-6271'}, 'institutions': [{'id': 'https://openalex.org/I133731052', 'display_name': 'University of Helsinki', 'ror': 'https://ror.org/040af2s02', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I133731052']}, {'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}, {'id': 'https://openalex.org/I2800229700', 'display_name': 'Helsinki Institute of Physics', 'ror': 'https://ror.org/01x2x1522', 'country_code': 'FI', 'type': 'facility', 'lineage': ['https://openalex.org/I133731052', 'https://openalex.org/I2800229700', 'https://openalex.org/I63548447', 'https://openalex.org/I94722563', 'https://openalex.org/I9927081']}, {'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}], 'countries': ['FI', 'US'], 'is_corresponding': False, 'raw_author_name': 'David G. Drubin', 'raw_affiliation_strings': ['*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'Institute of Biotechnology, 00014 University of Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': '*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I133731052', 'https://openalex.org/I1327163397']}, {'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'institution_ids': ['https://openalex.org/I95457486']}, {'raw_affiliation_string': 'Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2800229700', 'https://openalex.org/I133731052']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5074553110', 'display_name': 'David C. Amberg', 'orcid': 'https://orcid.org/0000-0002-4709-8848'}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I133731052', 'display_name': 'University of Helsinki', 'ror': 'https://ror.org/040af2s02', 'country_code': 'FI', 'type': 'education', 'lineage': ['https://openalex.org/I133731052']}, {'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}, {'id': 'https://openalex.org/I2800229700', 'display_name': 'Helsinki Institute of Physics', 'ror': 'https://ror.org/01x2x1522', 'country_code': 'FI', 'type': 'facility', 'lineage': ['https://openalex.org/I133731052', 'https://openalex.org/I2800229700', 'https://openalex.org/I63548447', 'https://openalex.org/I94722563', 'https://openalex.org/I9927081']}], 'countries': ['FI', 'US'], 'is_corresponding': True, 'raw_author_name': 'David C. Amberg', 'raw_affiliation_strings': ['*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'Institute of Biotechnology, 00014 University of Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': '*Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720; †State University of New York Health Science Center, Department of Biochemistry and Molecular Biology, Syracuse, New York 13210; and §Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I1327163397', 'https://openalex.org/I133731052']}, {'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720', 'institution_ids': ['https://openalex.org/I95457486']}, {'raw_affiliation_string': 'Institute of Biotechnology, 00014 University of Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2800229700', 'https://openalex.org/I133731052']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5074553110'], 'corresponding_institution_ids': ['https://openalex.org/I1327163397', 'https://openalex.org/I133731052', 'https://openalex.org/I95457486', 'https://openalex.org/I2800229700'], 'apc_list': None, 'apc_paid': None, 'fwci': 4.175, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 224, 'citation_normalized_percentile': {'value': 0.999781, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '145', 'issue': '6', 'first_page': '1251', 'last_page': '1264'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10379', 'display_name': 'Cellular Mechanics and Interactions', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10379', 'display_name': 'Cellular Mechanics and Interactions', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10882', 'display_name': 'Cardiomyopathy and Myosin Studies', 'score': 0.9811, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10540', 'display_name': 'Advanced Fluorescence Microscopy Techniques', 'score': 0.9718, 'subfield': {'id': 'https://openalex.org/subfields/1304', 'display_name': 'Biophysics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cofilin', 'display_name': 'Cofilin', 'score': 0.9831656}, {'id': 'https://openalex.org/keywords/actin-remodeling', 'display_name': 'Actin remodeling', 'score': 0.7910551}, {'id': 'https://openalex.org/keywords/mdia1', 'display_name': 'MDia1', 'score': 0.6202151}, {'id': 'https://openalex.org/keywords/actin-binding-protein', 'display_name': 'Actin-binding protein', 'score': 0.5940546}], 'concepts': [{'id': 'https://openalex.org/C2776601116', 'wikidata': 'https://www.wikidata.org/wiki/Q24786722', 'display_name': 'Cofilin', 'level': 5, 'score': 0.9831656}, {'id': 'https://openalex.org/C3620293', 'wikidata': 'https://www.wikidata.org/wiki/Q14908027', 'display_name': 'Actin remodeling', 'level': 5, 'score': 0.7910551}, {'id': 'https://openalex.org/C151000934', 'wikidata': 'https://www.wikidata.org/wiki/Q4676834', 'display_name': 'Actin remodeling of neurons', 'level': 5, 'score': 0.74592507}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.69917697}, {'id': 'https://openalex.org/C59999672', 'wikidata': 'https://www.wikidata.org/wiki/Q21497084', 'display_name': 'MDia1', 'level': 5, 'score': 0.6202151}, {'id': 'https://openalex.org/C125705527', 'wikidata': 'https://www.wikidata.org/wiki/Q185269', 'display_name': 'Actin', 'level': 2, 'score': 0.61936045}, {'id': 'https://openalex.org/C130861313', 'wikidata': 'https://www.wikidata.org/wiki/Q3775363', 'display_name': 'Actin-binding protein', 'level': 5, 'score': 0.5940546}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.47559676}, {'id': 'https://openalex.org/C2993400109', 'wikidata': 'https://www.wikidata.org/wiki/Q329638', 'display_name': 'Actin cytoskeleton', 'level': 4, 'score': 0.454479}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.33622038}, {'id': 'https://openalex.org/C142669718', 'wikidata': 'https://www.wikidata.org/wiki/Q154626', 'display_name': 'Cytoskeleton', 'level': 3, 'score': 0.29034972}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.14499128}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.047724545}], 'mesh': [{'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D051339', 'descriptor_name': 'Actin Depolymerizing Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000906', 'descriptor_name': 'Antibodies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005656', 'descriptor_name': 'Fungal Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D005804', 'descriptor_name': 'Genes, Lethal', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008840', 'descriptor_name': 'Microfilament Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011108', 'descriptor_name': 'Polymers', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D013816', 'descriptor_name': 'Thermodynamics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.145.6.1251', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2133144', 'pdf_url': 'https://europepmc.org/articles/pmc2133144?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133144', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10366597', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.145.6.1251', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W1526043578', 'https://openalex.org/W1539711621', 'https://openalex.org/W1593180325', 'https://openalex.org/W1594700207', 'https://openalex.org/W1602727746', 'https://openalex.org/W1875421809', 'https://openalex.org/W1967716439', 'https://openalex.org/W1970264680', 'https://openalex.org/W1978741325', 'https://openalex.org/W1981852445', 'https://openalex.org/W1984354326', 'https://openalex.org/W1986239975', 'https://openalex.org/W1999035343', 'https://openalex.org/W2009606782', 'https://openalex.org/W2011014242', 'https://openalex.org/W2020081859', 'https://openalex.org/W2026372765', 'https://openalex.org/W2026395694', 'https://openalex.org/W2028325183', 'https://openalex.org/W2033172386', 'https://openalex.org/W2035757021', 'https://openalex.org/W2057992913', 'https://openalex.org/W2068446924', 'https://openalex.org/W2073689795', 'https://openalex.org/W2076707408', 'https://openalex.org/W2082971375', 'https://openalex.org/W2089307620', 'https://openalex.org/W2117332681', 'https://openalex.org/W2125510211', 'https://openalex.org/W2130099579', 'https://openalex.org/W2141834983', 'https://openalex.org/W2146625122', 'https://openalex.org/W2163331732', 'https://openalex.org/W2164021052', 'https://openalex.org/W2169045417', 'https://openalex.org/W976139268'], 'related_works': ['https://openalex.org/W3003751606', 'https://openalex.org/W2755233762', 'https://openalex.org/W2620131906', 'https://openalex.org/W2119131795', 'https://openalex.org/W2100455753', 'https://openalex.org/W2084958568', 'https://openalex.org/W2083590644', 'https://openalex.org/W2066113543', 'https://openalex.org/W2011545163', 'https://openalex.org/W1965243001'], 'abstract_inverted_index': {'Actin': [0], 'interacting': [1], 'protein': [2, 153], '1': [3], '(Aip1)': [4], 'is': [5, 65, 99, 109, 150], 'a': [6, 16, 151], 'conserved': [7], 'component': [8], 'of': [9, 50, 61, 81, 127, 134, 141, 160], 'the': [10, 30, 48, 62, 79, 132, 156], 'actin': [11, 32, 42, 75, 82, 91, 103, 128, 144, 168], 'cytoskeleton': [12], 'first': [13], 'identified': [14, 44], 'in': [15, 55, 67, 85, 93, 131], 'two-hybrid': [17], 'screen': [18], 'against': [19], 'yeast': [20, 94], 'actin.': [21], 'Here,': [22], 'we': [23], 'report': [24], 'that': [25, 77, 122, 137, 148, 154], 'Aip1p': [26, 54, 87, 108, 123, 142, 149], 'also': [27], 'interacts': [28], 'with': [29, 69], 'ubiquitous': [31], 'depolymerizing': [33], 'factor': [34], 'cofilin.': [35], 'A': [36], 'two-hybrid–based': [37], 'approach': [38], 'using': [39], 'cofilin': [40, 70, 105, 113, 135, 138, 161, 164], 'and': [41, 53, 96, 104, 136, 162], 'mutants': [43, 71], 'residues': [45], 'necessary': [46], 'for': [47], 'interaction': [49], 'actin,': [51], 'cofilin,': [52], 'an': [56, 74], 'apparent': [57], 'ternary': [58], 'complex.': [59], 'Deletion': [60], 'AIP1': [63], 'gene': [64], 'lethal': [66], 'combination': [68], 'or': [72], 'act1-159,': [73], 'mutation': [76], 'slows': [78], 'rate': [80], 'filament': [83, 157], 'disassembly': [84, 158], 'vivo.': [86], 'localizes': [88], 'to': [89, 111, 115, 143, 166], 'cortical': [90, 116, 167], 'patches': [92], 'cells,': [95], 'this': [97], 'localization': [98, 114, 165], 'disrupted': [100], 'by': [101], 'specific': [102], 'mutations.': [106], 'Further,': [107], 'required': [110], 'restrict': [112], 'patches.': [117, 169], 'Finally,': [118], 'biochemical': [119], 'analyses': [120], 'show': [121], 'causes': [124], 'net': [125], 'depolymerization': [126], 'filaments': [129], 'only': [130], 'presence': [133], 'enhances': [139, 155], 'binding': [140], 'filaments.': [145], 'We': [146], 'conclude': [147], 'cofilin-associated': [152], 'activity': [159], 'restricts': [163]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2080945459', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 11}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2025-01-05T14:11:23.117654', 'created_date': '2016-06-24'}