Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2983462254', 'doi': 'https://doi.org/10.1016/j.addr.2019.09.003', 'title': 'Silk fibroin for skin injury repair: Where do things stand?', 'display_name': 'Silk fibroin for skin injury repair: Where do things stand?', 'publication_year': 2020, 'publication_date': '2020-01-01', 'ids': {'openalex': 'https://openalex.org/W2983462254', 'doi': 'https://doi.org/10.1016/j.addr.2019.09.003', 'mag': '2983462254', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/31678360'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.addr.2019.09.003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114437232', 'display_name': 'Advanced Drug Delivery Reviews', 'issn_l': '0169-409X', 'issn': ['0169-409X', '1872-8294'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5008151158', 'display_name': 'Mazaher Gholipourmalekabadi', 'orcid': 'https://orcid.org/0000-0001-6287-6831'}, 'institutions': [{'id': 'https://openalex.org/I161106909', 'display_name': 'Iran University of Medical Sciences', 'ror': 'https://ror.org/03w04rv71', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I161106909']}], 'countries': ['IR'], 'is_corresponding': True, 'raw_author_name': 'Mazaher Gholipourmalekabadi', 'raw_affiliation_strings': ['Cellular and Molecular Research Centre, Iran University of Medical Sciences, Tehran, Iran', 'Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran'], 'affiliations': [{'raw_affiliation_string': 'Cellular and Molecular Research Centre, Iran University of Medical Sciences, Tehran, Iran', 'institution_ids': ['https://openalex.org/I161106909']}, {'raw_affiliation_string': 'Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran', 'institution_ids': ['https://openalex.org/I161106909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013019417', 'display_name': 'Sunaina Sapru', 'orcid': 'https://orcid.org/0000-0003-1501-1071'}, 'institutions': [{'id': 'https://openalex.org/I145894827', 'display_name': 'Indian Institute of Technology Kharagpur', 'ror': 'https://ror.org/03w5sq511', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I145894827']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Sunaina Sapru', 'raw_affiliation_strings': ['Department of Biotechnology, Indian Institute of Technology Kharagpur, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Biotechnology, Indian Institute of Technology Kharagpur, India', 'institution_ids': ['https://openalex.org/I145894827']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073273376', 'display_name': 'Alí Samadikuchaksaraei', 'orcid': 'https://orcid.org/0000-0002-2108-9927'}, 'institutions': [{'id': 'https://openalex.org/I161106909', 'display_name': 'Iran University of Medical Sciences', 'ror': 'https://ror.org/03w04rv71', 'country_code': 'IR', 'type': 'education', 'lineage': ['https://openalex.org/I161106909']}], 'countries': ['IR'], 'is_corresponding': False, 'raw_author_name': 'Ali Samadikuchaksaraei', 'raw_affiliation_strings': ['Cellular and Molecular Research Centre, Iran University of Medical Sciences, Tehran, Iran', 'Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran'], 'affiliations': [{'raw_affiliation_string': 'Cellular and Molecular Research Centre, Iran University of Medical Sciences, Tehran, Iran', 'institution_ids': ['https://openalex.org/I161106909']}, {'raw_affiliation_string': 'Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran', 'institution_ids': ['https://openalex.org/I161106909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081499203', 'display_name': 'Rui L. Reis', 'orcid': 'https://orcid.org/0000-0002-4295-6129'}, 'institutions': [{'id': 'https://openalex.org/I99682543', 'display_name': 'University of Minho', 'ror': 'https://ror.org/037wpkx04', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I99682543']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Rui L. Reis', 'raw_affiliation_strings': ['3Bs Research Group, I3Bs - Research Institute on Biomaterials, Biodegradable and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimaraes, Portugal'], 'affiliations': [{'raw_affiliation_string': '3Bs Research Group, I3Bs - Research Institute on Biomaterials, Biodegradable and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimaraes, Portugal', 'institution_ids': ['https://openalex.org/I99682543']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057871048', 'display_name': 'David L. Kaplan', 'orcid': 'https://orcid.org/0000-0002-9245-7774'}, 'institutions': [{'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David L. Kaplan', 'raw_affiliation_strings': ['Department of Biomedical Engineering, Tufts University, Medford, MA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Engineering, Tufts University, Medford, MA, USA', 'institution_ids': ['https://openalex.org/I121934306']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007171563', 'display_name': 'Subhas C. Kundu', 'orcid': 'https://orcid.org/0000-0002-7170-2291'}, 'institutions': [{'id': 'https://openalex.org/I99682543', 'display_name': 'University of Minho', 'ror': 'https://ror.org/037wpkx04', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I99682543']}, {'id': 'https://openalex.org/I145894827', 'display_name': 'Indian Institute of Technology Kharagpur', 'ror': 'https://ror.org/03w5sq511', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I145894827']}], 'countries': ['IN', 'PT'], 'is_corresponding': True, 'raw_author_name': 'Subhas C. Kundu', 'raw_affiliation_strings': ['3Bs Research Group, I3Bs - Research Institute on Biomaterials, Biodegradable and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimaraes, Portugal', 'Department of Biotechnology, Indian Institute of Technology Kharagpur, India'], 'affiliations': [{'raw_affiliation_string': '3Bs Research Group, I3Bs - Research Institute on Biomaterials, Biodegradable and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimaraes, Portugal', 'institution_ids': ['https://openalex.org/I99682543']}, {'raw_affiliation_string': 'Department of Biotechnology, Indian Institute of Technology Kharagpur, India', 'institution_ids': ['https://openalex.org/I145894827']}]}], 'countries_distinct_count': 4, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5008151158', 'https://openalex.org/A5007171563'], 'corresponding_institution_ids': ['https://openalex.org/I161106909', 'https://openalex.org/I99682543', 'https://openalex.org/I145894827'], 'apc_list': {'value': 5150, 'currency': 'USD', 'value_usd': 5150, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.188, 'has_fulltext': False, 'cited_by_count': 187, 'citation_normalized_percentile': {'value': 0.996875, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '153', 'issue': None, 'first_page': '28', 'last_page': '53'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11966', 'display_name': 'Biomedical Applications of Silk Biomaterials', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2502', 'display_name': 'Biomaterials'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11966', 'display_name': 'Biomedical Applications of Silk Biomaterials', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2502', 'display_name': 'Biomaterials'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10729', 'display_name': 'Electrospun Nanofibers in Biomedical Applications', 'score': 0.9876, 'subfield': {'id': 'https://openalex.org/subfields/2502', 'display_name': 'Biomaterials'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10859', 'display_name': 'Mussel-Inspired Surface Chemistry for Multifunctional Coatings', 'score': 0.9449, 'subfield': {'id': 'https://openalex.org/subfields/2508', 'display_name': 'Surfaces, Coatings and Films'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/fibroin', 'display_name': 'Fibroin', 'score': 0.9964285}, {'id': 'https://openalex.org/keywords/biomaterial', 'display_name': 'Biomaterial', 'score': 0.90201455}, {'id': 'https://openalex.org/keywords/sericin', 'display_name': 'Sericin', 'score': 0.76122}, {'id': 'https://openalex.org/keywords/biocompatibility', 'display_name': 'Biocompatibility', 'score': 0.7208462}, {'id': 'https://openalex.org/keywords/silk-fibroin', 'display_name': 'Silk Fibroin', 'score': 0.572958}, {'id': 'https://openalex.org/keywords/tissue-engineering', 'display_name': 'Tissue Engineering', 'score': 0.510758}], 'concepts': [{'id': 'https://openalex.org/C122302759', 'wikidata': 'https://www.wikidata.org/wiki/Q2345087', 'display_name': 'Fibroin', 'level': 3, 'score': 0.9964285}, {'id': 'https://openalex.org/C2778414984', 'wikidata': 'https://www.wikidata.org/wiki/Q865663', 'display_name': 'Biomaterial', 'level': 2, 'score': 0.90201455}, {'id': 'https://openalex.org/C206767735', 'wikidata': 'https://www.wikidata.org/wiki/Q2983186', 'display_name': 'Sericin', 'level': 3, 'score': 0.76122}, {'id': 'https://openalex.org/C2777230088', 'wikidata': 'https://www.wikidata.org/wiki/Q864426', 'display_name': 'Biocompatibility', 'level': 2, 'score': 0.7208462}, {'id': 'https://openalex.org/C2780431358', 'wikidata': 'https://www.wikidata.org/wiki/Q653622', 'display_name': 'SILK', 'level': 2, 'score': 0.68826914}, {'id': 'https://openalex.org/C49892992', 'wikidata': 'https://www.wikidata.org/wiki/Q1540285', 'display_name': 'Tissue engineering', 'level': 2, 'score': 0.63157696}, {'id': 'https://openalex.org/C89429830', 'wikidata': 'https://www.wikidata.org/wiki/Q735710', 'display_name': 'Scaffold', 'level': 2, 'score': 0.55888873}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.55012405}, {'id': 'https://openalex.org/C108586683', 'wikidata': 'https://www.wikidata.org/wiki/Q17164826', 'display_name': 'Self-healing hydrogels', 'level': 2, 'score': 0.5200914}, {'id': 'https://openalex.org/C2780269544', 'wikidata': 'https://www.wikidata.org/wiki/Q1509074', 'display_name': 'Wound healing', 'level': 2, 'score': 0.444464}, {'id': 'https://openalex.org/C136229726', 'wikidata': 'https://www.wikidata.org/wiki/Q327092', 'display_name': 'Biomedical engineering', 'level': 1, 'score': 0.4259566}, {'id': 'https://openalex.org/C171250308', 'wikidata': 'https://www.wikidata.org/wiki/Q11468', 'display_name': 'Nanotechnology', 'level': 1, 'score': 0.32983762}, {'id': 'https://openalex.org/C126348684', 'wikidata': 'https://www.wikidata.org/wiki/Q3456979', 'display_name': 'Polymer science', 'level': 1, 'score': 0.32027048}, {'id': 'https://openalex.org/C159985019', 'wikidata': 'https://www.wikidata.org/wiki/Q181790', 'display_name': 'Composite material', 'level': 1, 'score': 0.111120015}, {'id': 'https://openalex.org/C188027245', 'wikidata': 'https://www.wikidata.org/wiki/Q750446', 'display_name': 'Polymer chemistry', 'level': 1, 'score': 0.095960975}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.08694419}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.077632695}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.061120242}, {'id': 'https://openalex.org/C191897082', 'wikidata': 'https://www.wikidata.org/wiki/Q11467', 'display_name': 'Metallurgy', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005349', 'descriptor_name': 'Fibroins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D005349', 'descriptor_name': 'Fibroins', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D023822', 'descriptor_name': 'Tissue Engineering', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D014947', 'descriptor_name': 'Wounds and Injuries', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D020341', 'descriptor_name': 'Absorbable Implants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001672', 'descriptor_name': 'Biocompatible Materials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001696', 'descriptor_name': 'Biomechanical Phenomena', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048708', 'descriptor_name': 'Cell Growth Processes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048708', 'descriptor_name': 'Cell Growth Processes', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005349', 'descriptor_name': 'Fibroins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005349', 'descriptor_name': 'Fibroins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023822', 'descriptor_name': 'Tissue Engineering', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054457', 'descriptor_name': 'Tissue Scaffolds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014945', 'descriptor_name': 'Wound Healing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014945', 'descriptor_name': 'Wound Healing', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D014947', 'descriptor_name': 'Wounds and Injuries', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.addr.2019.09.003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114437232', 'display_name': 'Advanced Drug Delivery Reviews', 'issn_l': '0169-409X', 'issn': ['0169-409X', '1872-8294'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/31678360', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320335254', 'funder_display_name': 'Horizon 2020', 'award_id': '668983 — FoReCaST'}], 'datasets': [], 'versions': [], 'referenced_works_count': 284, 'referenced_works': ['https://openalex.org/W1176145749', 'https://openalex.org/W1423191041', 'https://openalex.org/W1482004695', 'https://openalex.org/W1545335825', 'https://openalex.org/W1590046357', 'https://openalex.org/W1602933791', 'https://openalex.org/W1604097892', 'https://openalex.org/W1604975193', 'https://openalex.org/W163449651', 'https://openalex.org/W1844628034', 'https://openalex.org/W1848457715', 'https://openalex.org/W1855227439', 'https://openalex.org/W1908881876', 'https://openalex.org/W1918732421', 'https://openalex.org/W1922444122', 'https://openalex.org/W1949832432', 'https://openalex.org/W1965324241', 'https://openalex.org/W1965453968', 'https://openalex.org/W1967581036', 'https://openalex.org/W1969799738', 'https://openalex.org/W1975425673', 'https://openalex.org/W1977256998', 'https://openalex.org/W1978122014', 'https://openalex.org/W1978138022', 'https://openalex.org/W1978265901', 'https://openalex.org/W1979795035', 'https://openalex.org/W1980352405', 'https://openalex.org/W1980902990', 'https://openalex.org/W1981762071', 'https://openalex.org/W1982380369', 'https://openalex.org/W1982788424', 'https://openalex.org/W1983104834', 'https://openalex.org/W1983707837', 'https://openalex.org/W1984983173', 'https://openalex.org/W1985058433', 'https://openalex.org/W1985386364', 'https://openalex.org/W1986308133', 'https://openalex.org/W1987341205', 'https://openalex.org/W1988510537', 'https://openalex.org/W1988721141', 'https://openalex.org/W1989522391', 'https://openalex.org/W1997085921', 'https://openalex.org/W1997686152', 'https://openalex.org/W1998754581', 'https://openalex.org/W2002207067', 'https://openalex.org/W2003258297', 'https://openalex.org/W2005079126', 'https://openalex.org/W2005586112', 'https://openalex.org/W2005987631', 'https://openalex.org/W2006338705', 'https://openalex.org/W2006883088', 'https://openalex.org/W2007845729', 'https://openalex.org/W2007924064', 'https://openalex.org/W2008115225', 'https://openalex.org/W2008718474', 'https://openalex.org/W2008850772', 'https://openalex.org/W2010011305', 'https://openalex.org/W2012836496', 'https://openalex.org/W2014068204', 'https://openalex.org/W2016972532', 'https://openalex.org/W2017213361', 'https://openalex.org/W2018482527', 'https://openalex.org/W2018507941', 'https://openalex.org/W2018653426', 'https://openalex.org/W2019364394', 'https://openalex.org/W2019488181', 'https://openalex.org/W2019711191', 'https://openalex.org/W2021061126', 'https://openalex.org/W2024250498', 'https://openalex.org/W2025846851', 'https://openalex.org/W2026230444', 'https://openalex.org/W2026799007', 'https://openalex.org/W2028255228', 'https://openalex.org/W2029014427', 'https://openalex.org/W2029937516', 'https://openalex.org/W2032319635', 'https://openalex.org/W2035519230', 'https://openalex.org/W2035560364', 'https://openalex.org/W2035812646', 'https://openalex.org/W2036045458', 'https://openalex.org/W2037810763', 'https://openalex.org/W2038102774', 'https://openalex.org/W2038196897', 'https://openalex.org/W2038987199', 'https://openalex.org/W2039131853', 'https://openalex.org/W2039290751', 'https://openalex.org/W2039944519', 'https://openalex.org/W2040469730', 'https://openalex.org/W2041591721', 'https://openalex.org/W2041723514', 'https://openalex.org/W2042509194', 'https://openalex.org/W2045830393', 'https://openalex.org/W2049399163', 'https://openalex.org/W2052043318', 'https://openalex.org/W2052116137', 'https://openalex.org/W2052991752', 'https://openalex.org/W2054988877', 'https://openalex.org/W2057999738', 'https://openalex.org/W2060692136', 'https://openalex.org/W2060828993', 'https://openalex.org/W2061073363', 'https://openalex.org/W2061416118', 'https://openalex.org/W2062066001', 'https://openalex.org/W2067601928', 'https://openalex.org/W2069406710', 'https://openalex.org/W2070333171', 'https://openalex.org/W2071805817', 'https://openalex.org/W2072002929', 'https://openalex.org/W2073137596', 'https://openalex.org/W2078072567', 'https://openalex.org/W2078755127', 'https://openalex.org/W2080011993', 'https://openalex.org/W2081094917', 'https://openalex.org/W2083884654', 'https://openalex.org/W2085293124', 'https://openalex.org/W2085924614', 'https://openalex.org/W2087850490', 'https://openalex.org/W2088266228', 'https://openalex.org/W2088373632', 'https://openalex.org/W2089222148', 'https://openalex.org/W2091202623', 'https://openalex.org/W2099357599', 'https://openalex.org/W2101601223', 'https://openalex.org/W2106225841', 'https://openalex.org/W2109226930', 'https://openalex.org/W2109380870', 'https://openalex.org/W2110569167', 'https://openalex.org/W2117808317', 'https://openalex.org/W2118927867', 'https://openalex.org/W2119888223', 'https://openalex.org/W2120279340', 'https://openalex.org/W2123918445', 'https://openalex.org/W2124111318', 'https://openalex.org/W2124195334', 'https://openalex.org/W2131281032', 'https://openalex.org/W2131837055', 'https://openalex.org/W2132477880', 'https://openalex.org/W2134208433', 'https://openalex.org/W2139653505', 'https://openalex.org/W2145304291', 'https://openalex.org/W2148383254', 'https://openalex.org/W2148399690', 'https://openalex.org/W2148430806', 'https://openalex.org/W2150295226', 'https://openalex.org/W2151132896', 'https://openalex.org/W2151602522', 'https://openalex.org/W2154659743', 'https://openalex.org/W2155800892', 'https://openalex.org/W2157134073', 'https://openalex.org/W2158312275', 'https://openalex.org/W2166181129', 'https://openalex.org/W2169220536', 'https://openalex.org/W2169336903', 'https://openalex.org/W2170869698', 'https://openalex.org/W2171312335', 'https://openalex.org/W2174489801', 'https://openalex.org/W2194403197', 'https://openalex.org/W2204595434', 'https://openalex.org/W2219036997', 'https://openalex.org/W2246034168', 'https://openalex.org/W2268667221', 'https://openalex.org/W2269848866', 'https://openalex.org/W2271845072', 'https://openalex.org/W2297642167', 'https://openalex.org/W2303675549', 'https://openalex.org/W2314387266', 'https://openalex.org/W2326276889', 'https://openalex.org/W2333901041', 'https://openalex.org/W2335343645', 'https://openalex.org/W2344713260', 'https://openalex.org/W2346389198', 'https://openalex.org/W2346457548', 'https://openalex.org/W2346674852', 'https://openalex.org/W2353982544', 'https://openalex.org/W2356346656', 'https://openalex.org/W2403939314', 'https://openalex.org/W2411723649', 'https://openalex.org/W2412736489', 'https://openalex.org/W2415126249', 'https://openalex.org/W2416189079', 'https://openalex.org/W2417386059', 'https://openalex.org/W2466203152', 'https://openalex.org/W2471222887', 'https://openalex.org/W2488288516', 'https://openalex.org/W2488446894', 'https://openalex.org/W2503933036', 'https://openalex.org/W2513761143', 'https://openalex.org/W2514356165', 'https://openalex.org/W2517027381', 'https://openalex.org/W2530589003', 'https://openalex.org/W2536484449', 'https://openalex.org/W2547570674', 'https://openalex.org/W2551545217', 'https://openalex.org/W2553929182', 'https://openalex.org/W2559860122', 'https://openalex.org/W2561638865', 'https://openalex.org/W2566379986', 'https://openalex.org/W2569716888', 'https://openalex.org/W2572561788', 'https://openalex.org/W2579362891', 'https://openalex.org/W2579920203', 'https://openalex.org/W2579921471', 'https://openalex.org/W2583466011', 'https://openalex.org/W2586398179', 'https://openalex.org/W2592394097', 'https://openalex.org/W2592584762', 'https://openalex.org/W2597324832', 'https://openalex.org/W2602820208', 'https://openalex.org/W2605897077', 'https://openalex.org/W2605931325', 'https://openalex.org/W2606379740', 'https://openalex.org/W2607207960', 'https://openalex.org/W2610723069', 'https://openalex.org/W2612704026', 'https://openalex.org/W2621178768', 'https://openalex.org/W2622003939', 'https://openalex.org/W2626974408', 'https://openalex.org/W2678101685', 'https://openalex.org/W2694518717', 'https://openalex.org/W2708504375', 'https://openalex.org/W271191850', 'https://openalex.org/W2725014077', 'https://openalex.org/W2732125787', 'https://openalex.org/W2732467616', 'https://openalex.org/W2733616517', 'https://openalex.org/W2734565470', 'https://openalex.org/W2750663738', 'https://openalex.org/W2751208375', 'https://openalex.org/W2751776294', 'https://openalex.org/W2751830938', 'https://openalex.org/W2752845195', 'https://openalex.org/W2755340412', 'https://openalex.org/W2756243705', 'https://openalex.org/W2761724645', 'https://openalex.org/W2761940021', 'https://openalex.org/W2763429484', 'https://openalex.org/W2765104909', 'https://openalex.org/W2765171297', 'https://openalex.org/W2767171374', 'https://openalex.org/W2767280943', 'https://openalex.org/W2774372483', 'https://openalex.org/W2782975866', 'https://openalex.org/W2788144271', 'https://openalex.org/W2789670971', 'https://openalex.org/W2789761495', 'https://openalex.org/W2789972858', 'https://openalex.org/W2792005867', 'https://openalex.org/W2792542396', 'https://openalex.org/W2793002331', 'https://openalex.org/W2793131599', 'https://openalex.org/W2794196436', 'https://openalex.org/W2794298996', 'https://openalex.org/W2794319453', 'https://openalex.org/W2794339160', 'https://openalex.org/W2795530700', 'https://openalex.org/W2797941151', 'https://openalex.org/W2799712561', 'https://openalex.org/W2799969169', 'https://openalex.org/W2801007809', 'https://openalex.org/W2801476438', 'https://openalex.org/W2803483052', 'https://openalex.org/W2804154788', 'https://openalex.org/W2804266586', 'https://openalex.org/W2804439559', 'https://openalex.org/W2811148766', 'https://openalex.org/W2887462591', 'https://openalex.org/W2896640500', 'https://openalex.org/W2899349321', 'https://openalex.org/W2903123904', 'https://openalex.org/W2904459033', 'https://openalex.org/W2904757639', 'https://openalex.org/W2913448385', 'https://openalex.org/W2914095071', 'https://openalex.org/W2915949427', 'https://openalex.org/W2932475686', 'https://openalex.org/W2947461678', 'https://openalex.org/W2970126101', 'https://openalex.org/W302522192', 'https://openalex.org/W3032120467', 'https://openalex.org/W4231709355', 'https://openalex.org/W4239753470', 'https://openalex.org/W4243085980', 'https://openalex.org/W4285719527', 'https://openalex.org/W757371209'], 'related_works': ['https://openalex.org/W4391997195', 'https://openalex.org/W4285148989', 'https://openalex.org/W32378388', 'https://openalex.org/W3203983557', 'https://openalex.org/W2941624622', 'https://openalex.org/W2417644990', 'https://openalex.org/W2342164541', 'https://openalex.org/W2217722057', 'https://openalex.org/W2063584003', 'https://openalex.org/W2020778361'], 'abstract_inverted_index': {'Several': [0], 'synthetic': [1], 'and': [2, 11, 51, 70, 98, 108, 127, 152, 166], 'natural': [3, 147], 'materials': [4, 66, 191], 'are': [5, 139], 'used': [6, 59, 184], 'in': [7, 46, 62, 67, 111, 136, 187, 192, 218, 225], 'soft': [8, 156], 'tissue': [9, 96, 157, 220], 'engineering': [10, 97, 158, 221], 'regenerative': [12], 'medicine': [13], 'with': [14, 64, 149, 189], 'varying': [15], 'degrees': [16], 'of': [17, 53, 82, 114, 129, 177, 232, 243], 'success.': [18], 'Among': [19], 'them,': [20], 'silkworm': [21], 'silk': [22, 89, 115, 130, 213, 244], 'protein': [23, 143, 179], 'fibroin,': [24], 'a': [25, 73, 133, 146], 'naturally': [26], 'occurring': [27], 'protein-based': [28], 'biomaterial,': [29], 'exhibits': [30], 'many': [31], 'promising': [32, 74, 106, 241], 'characteristics': [33, 107, 242], 'such': [34, 83, 196], 'as': [35, 80, 132, 197], 'biocompatibility,': [36], 'controllable': [37], 'biodegradability,': [38], 'tunable': [39], 'mechanical': [40, 153], 'properties,': [41], 'aqueous': [42], 'preparation,': [43], 'minimal': [44], 'inflammation': [45], 'host': [47], 'tissue,': [48], 'low': [49], 'cost': [50], 'ease': [52], 'use.': [54], 'Silk': [55, 142, 160], 'fibroin': [56, 90, 116, 131, 144, 161, 214, 245], 'is': [57, 71, 145, 162, 183], 'often': [58], 'alone': [60, 185], 'or': [61, 172, 186, 202, 215], 'combination': [63, 188], 'other': [65, 190], 'various': [68], 'formats': [69], 'also': [72, 140], 'delivery': [75], 'system': [76], 'for': [77, 94, 117, 155, 205, 246], 'bioactive': [78], 'compounds': [79], 'part': [81], 'repair': [84, 99, 123, 252], 'scenarios.': [85], 'These': [86], 'properties': [87, 154], 'make': [88], 'an': [91], 'excellent': [92], 'biomaterial': [93, 135, 148], 'skin': [95, 118, 219, 247], 'applications.': [100, 124, 159, 207, 253], 'This': [101, 236], 'review': [102, 237], 'focuses': [103, 238], 'on': [104, 239], 'the': [105, 112, 230, 240], 'recent': [109, 226], 'advances': [110], 'use': [113], 'wound': [119, 248], 'healing': [120, 249], 'and/or': [121, 250], 'soft-tissue': [122, 251], 'The': [125, 208], 'benefits': [126], 'limitations': [128], 'scaffolding': [134], 'this': [137, 233], 'context': [138], 'discussed.': [141], 'important': [150], 'biological': [151], 'obtained': [163], 'from': [164], 'silkworms': [165], 'can': [167], 'be': [168], 'purified': [169], 'using': [170, 212], 'alkali': [171], 'enzyme': [173], 'based': [174], 'degumming': [175], '(removal': [176], 'glue': [178], 'sericin)': [180], 'procedures.': [181], 'Fibroin': [182], 'different': [193], 'scaffold': [194], 'forms,': [195], 'nanofibrous': [198], 'mats,': [199], 'hydrogels,': [200], 'sponges': [201], 'films': [203], 'tailored': [204], 'specific': [206], 'investigations': [209], 'carried': [210], 'out': [211], 'its': [216], 'blends': [217], 'have': [222], 'increased': [223], 'dramatically': [224], 'years': [227], 'due': [228], 'to': [229], 'advantages': [231], 'unique': [234], 'biomaterial.': [235]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2983462254', 'counts_by_year': [{'year': 2024, 'cited_by_count': 58}, {'year': 2023, 'cited_by_count': 33}, {'year': 2022, 'cited_by_count': 48}, {'year': 2021, 'cited_by_count': 33}, {'year': 2020, 'cited_by_count': 14}], 'updated_date': '2024-09-06T12:33:12.128741', 'created_date': '2019-11-22'}