Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2841848923', 'doi': 'https://doi.org/10.1111/eci.12996', 'title': 'Hypothalamic <scp>AMPK</scp> and energy balance', 'display_name': 'Hypothalamic <scp>AMPK</scp> and energy balance', 'publication_year': 2018, 'publication_date': '2018-07-12', 'ids': {'openalex': 'https://openalex.org/W2841848923', 'doi': 'https://doi.org/10.1111/eci.12996', 'mag': '2841848923', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29999521', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6175178'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/eci.12996', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/eci.12996', 'source': {'id': 'https://openalex.org/S153084679', 'display_name': 'European Journal of Clinical Investigation', 'issn_l': '0014-2972', 'issn': ['0014-2972', '1365-2362'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/eci.12996', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100657656', 'display_name': 'Miguel López', 'orcid': 'https://orcid.org/0000-0002-7823-1648'}, 'institutions': [{'id': 'https://openalex.org/I4210115082', 'display_name': 'Centro de Investigación Biomédica en Red', 'ror': 'https://ror.org/02g87qh62', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I2801357902', 'https://openalex.org/I4210115082', 'https://openalex.org/I4387152914']}, {'id': 'https://openalex.org/I4210148771', 'display_name': 'Instituto de Investigación Sanitaria de Santiago', 'ror': 'https://ror.org/05n7xcf53', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I4210148771']}, {'id': 'https://openalex.org/I200284239', 'display_name': 'Universidade de Santiago de Compostela', 'ror': 'https://ror.org/030eybx10', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I200284239']}], 'countries': ['ES'], 'is_corresponding': True, 'raw_author_name': 'Miguel López', 'raw_affiliation_strings': ['CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) Santiago de Compostela Spain', 'NeurObesity Group Department of Physiology CIMUS University of Santiago de Compostela‐Instituto de Investigación Sanitaria Santiago de Compostela Spain'], 'affiliations': [{'raw_affiliation_string': 'CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) Santiago de Compostela Spain', 'institution_ids': ['https://openalex.org/I4210115082']}, {'raw_affiliation_string': 'NeurObesity Group Department of Physiology CIMUS University of Santiago de Compostela‐Instituto de Investigación Sanitaria Santiago de Compostela Spain', 'institution_ids': ['https://openalex.org/I4210148771', 'https://openalex.org/I200284239']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5100657656'], 'corresponding_institution_ids': ['https://openalex.org/I4210115082', 'https://openalex.org/I4210148771', 'https://openalex.org/I200284239'], 'apc_list': {'value': 3710, 'currency': 'USD', 'value_usd': 3710, 'provenance': 'doaj'}, 'apc_paid': {'value': 3710, 'currency': 'USD', 'value_usd': 3710, 'provenance': 'doaj'}, 'fwci': 1.337, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 95, 'citation_normalized_percentile': {'value': 0.413435, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '48', 'issue': '9', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11339', 'display_name': 'Metabolism, Diabetes, and Cancer', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11339', 'display_name': 'Metabolism, Diabetes, and Cancer', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10839', 'display_name': 'Pancreatic function and diabetes', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11457', 'display_name': 'Adipose Tissue and Metabolism', 'score': 0.9903, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/energy-homeostasis', 'display_name': 'Energy homeostasis', 'score': 0.58668566}], 'concepts': [{'id': 'https://openalex.org/C2780124434', 'wikidata': 'https://www.wikidata.org/wiki/Q12357464', 'display_name': 'AMPK', 'level': 4, 'score': 0.9588219}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.6461129}, {'id': 'https://openalex.org/C2491326', 'wikidata': 'https://www.wikidata.org/wiki/Q5377024', 'display_name': 'Energy homeostasis', 'level': 3, 'score': 0.58668566}, {'id': 'https://openalex.org/C151955695', 'wikidata': 'https://www.wikidata.org/wiki/Q654528', 'display_name': 'White adipose tissue', 'level': 3, 'score': 0.5810851}, {'id': 'https://openalex.org/C151279926', 'wikidata': 'https://www.wikidata.org/wiki/Q965695', 'display_name': 'Thermogenesis', 'level': 3, 'score': 0.57481855}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5697804}, {'id': 'https://openalex.org/C97029542', 'wikidata': 'https://www.wikidata.org/wiki/Q281417', 'display_name': 'Protein kinase A', 'level': 3, 'score': 0.5085789}, {'id': 'https://openalex.org/C171089720', 'wikidata': 'https://www.wikidata.org/wiki/Q193583', 'display_name': 'Adipose tissue', 'level': 2, 'score': 0.45714313}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.43855458}, {'id': 'https://openalex.org/C2780323712', 'wikidata': 'https://www.wikidata.org/wiki/Q19484', 'display_name': 'Metformin', 'level': 3, 'score': 0.43294093}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37862444}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3145905}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.29342568}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.20582184}, {'id': 'https://openalex.org/C184235292', 'wikidata': 'https://www.wikidata.org/wiki/Q421851', 'display_name': 'Kinase', 'level': 2, 'score': 0.18704289}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.17138013}, {'id': 'https://openalex.org/C511355011', 'wikidata': 'https://www.wikidata.org/wiki/Q12174', 'display_name': 'Obesity', 'level': 2, 'score': 0.11876264}], 'mesh': [{'descriptor_ui': 'D055372', 'descriptor_name': 'AMP-Activated Protein Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D007031', 'descriptor_name': 'Hypothalamus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D055372', 'descriptor_name': 'AMP-Activated Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002001', 'descriptor_name': 'Adipose Tissue, Brown', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002001', 'descriptor_name': 'Adipose Tissue, Brown', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D052436', 'descriptor_name': 'Adipose Tissue, White', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052436', 'descriptor_name': 'Adipose Tissue, White', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019440', 'descriptor_name': 'Anti-Obesity Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005247', 'descriptor_name': 'Feeding Behavior', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007004', 'descriptor_name': 'Hypoglycemic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007031', 'descriptor_name': 'Hypothalamus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000069450', 'descriptor_name': 'Liraglutide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008687', 'descriptor_name': 'Metformin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009132', 'descriptor_name': 'Muscles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009132', 'descriptor_name': 'Muscles', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009538', 'descriptor_name': 'Nicotine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018722', 'descriptor_name': 'Nicotinic Agonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D022722', 'descriptor_name': 'Thermogenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015430', 'descriptor_name': 'Weight Gain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/eci.12996', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/eci.12996', 'source': {'id': 'https://openalex.org/S153084679', 'display_name': 'European Journal of Clinical Investigation', 'issn_l': '0014-2972', 'issn': ['0014-2972', '1365-2362'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6175178', 'pdf_url': 'https://europepmc.org/articles/pmc6175178?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175178', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29999521', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/eci.12996', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/eci.12996', 'source': {'id': 'https://openalex.org/S153084679', 'display_name': 'European Journal of Clinical Investigation', 'issn_l': '0014-2972', 'issn': ['0014-2972', '1365-2362'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/7', 'display_name': 'Affordable and clean energy', 'score': 0.87}], 'grants': [{'funder': 'https://openalex.org/F4320321837', 'funder_display_name': 'Ministerio de Economía y Competitividad', 'award_id': 'SAF2015‐71026‐R'}], 'datasets': [], 'versions': [], 'referenced_works_count': 146, 'referenced_works': ['https://openalex.org/W1518235890', 'https://openalex.org/W1522146641', 'https://openalex.org/W1565979608', 'https://openalex.org/W168671060', 'https://openalex.org/W1691578538', 'https://openalex.org/W1793811107', 'https://openalex.org/W1965885099', 'https://openalex.org/W1966706887', 'https://openalex.org/W1968069807', 'https://openalex.org/W1968473351', 'https://openalex.org/W1970637701', 'https://openalex.org/W1972091423', 'https://openalex.org/W1973749169', 'https://openalex.org/W1980781994', 'https://openalex.org/W1982247506', 'https://openalex.org/W1984985876', 'https://openalex.org/W1986804512', 'https://openalex.org/W1988803699', 'https://openalex.org/W1990278643', 'https://openalex.org/W1990534697', 'https://openalex.org/W1991630431', 'https://openalex.org/W1994554353', 'https://openalex.org/W1995069275', 'https://openalex.org/W1995352580', 'https://openalex.org/W1997332398', 'https://openalex.org/W2004401015', 'https://openalex.org/W2005563324', 'https://openalex.org/W2008026539', 'https://openalex.org/W2008572972', 'https://openalex.org/W2010238890', 'https://openalex.org/W2011001343', 'https://openalex.org/W2012238179', 'https://openalex.org/W2012390470', 'https://openalex.org/W2013090884', 'https://openalex.org/W2015501861', 'https://openalex.org/W2016752484', 'https://openalex.org/W2019683289', 'https://openalex.org/W2019982745', 'https://openalex.org/W2020349073', 'https://openalex.org/W2020843850', 'https://openalex.org/W2021128495', 'https://openalex.org/W2026413615', 'https://openalex.org/W2027922318', 'https://openalex.org/W2028502361', 'https://openalex.org/W2030636484', 'https://openalex.org/W2032065353', 'https://openalex.org/W2033497590', 'https://openalex.org/W2033823674', 'https://openalex.org/W2035651268', 'https://openalex.org/W2037918682', 'https://openalex.org/W2040632043', 'https://openalex.org/W2042444876', 'https://openalex.org/W2042950036', 'https://openalex.org/W2044644735', 'https://openalex.org/W2045085761', 'https://openalex.org/W2045966750', 'https://openalex.org/W2046946656', 'https://openalex.org/W2047192792', 'https://openalex.org/W2057218469', 'https://openalex.org/W2057793858', 'https://openalex.org/W2065705538', 'https://openalex.org/W2067013073', 'https://openalex.org/W2067979493', 'https://openalex.org/W2068383276', 'https://openalex.org/W2070910260', 'https://openalex.org/W2072912523', 'https://openalex.org/W2074303577', 'https://openalex.org/W2074894911', 'https://openalex.org/W2077033935', 'https://openalex.org/W2078987164', 'https://openalex.org/W2080107084', 'https://openalex.org/W2080369665', 'https://openalex.org/W2080680563', 'https://openalex.org/W2084519942', 'https://openalex.org/W2085181449', 'https://openalex.org/W2085412379', 'https://openalex.org/W2085567056', 'https://openalex.org/W2087212409', 'https://openalex.org/W2091469763', 'https://openalex.org/W2091795452', 'https://openalex.org/W2095327289', 'https://openalex.org/W2095358591', 'https://openalex.org/W2095454212', 'https://openalex.org/W2096591765', 'https://openalex.org/W2098947405', 'https://openalex.org/W2099906268', 'https://openalex.org/W2100538674', 'https://openalex.org/W2102843766', 'https://openalex.org/W2102891343', 'https://openalex.org/W2103450921', 'https://openalex.org/W2103659405', 'https://openalex.org/W2103986580', 'https://openalex.org/W2107227663', 'https://openalex.org/W2108365604', 'https://openalex.org/W2110804432', 'https://openalex.org/W2111413580', 'https://openalex.org/W2113593419', 'https://openalex.org/W2114147584', 'https://openalex.org/W2114339108', 'https://openalex.org/W2115945915', 'https://openalex.org/W2123014930', 'https://openalex.org/W2124690759', 'https://openalex.org/W2128485668', 'https://openalex.org/W2132358997', 'https://openalex.org/W2134907909', 'https://openalex.org/W2135300530', 'https://openalex.org/W2135704900', 'https://openalex.org/W2135897497', 'https://openalex.org/W2140808124', 'https://openalex.org/W2145865543', 'https://openalex.org/W2147571221', 'https://openalex.org/W2148694780', 'https://openalex.org/W2157540558', 'https://openalex.org/W2159444491', 'https://openalex.org/W2159536456', 'https://openalex.org/W2159620999', 'https://openalex.org/W2160033930', 'https://openalex.org/W2164577763', 'https://openalex.org/W2165844677', 'https://openalex.org/W2169520827', 'https://openalex.org/W2169612876', 'https://openalex.org/W2171804530', 'https://openalex.org/W2174118934', 'https://openalex.org/W2179736561', 'https://openalex.org/W2256418959', 'https://openalex.org/W2320228393', 'https://openalex.org/W2335690375', 'https://openalex.org/W2402553346', 'https://openalex.org/W2471889258', 'https://openalex.org/W2504453637', 'https://openalex.org/W2507223877', 'https://openalex.org/W2507234330', 'https://openalex.org/W2515318044', 'https://openalex.org/W2517419181', 'https://openalex.org/W2519369640', 'https://openalex.org/W2528971420', 'https://openalex.org/W2531523386', 'https://openalex.org/W2558408965', 'https://openalex.org/W2590195408', 'https://openalex.org/W2600891164', 'https://openalex.org/W2727251727', 'https://openalex.org/W2749942745', 'https://openalex.org/W2783607456', 'https://openalex.org/W2785340274', 'https://openalex.org/W55232514', 'https://openalex.org/W568183490'], 'related_works': ['https://openalex.org/W4281562259', 'https://openalex.org/W3146205273', 'https://openalex.org/W3142564810', 'https://openalex.org/W3134072345', 'https://openalex.org/W3029291832', 'https://openalex.org/W2922116003', 'https://openalex.org/W2763780577', 'https://openalex.org/W2751676921', 'https://openalex.org/W2484249338', 'https://openalex.org/W1521090039'], 'abstract_inverted_index': {'AMP-activated': [0], 'protein': [1], 'kinase': [2], '(AMPK)': [3], 'is': [4, 52], 'the': [5, 21, 36, 117, 158, 162], 'main': [6], 'cellular': [7, 15], 'energy': [8, 16, 22, 26, 30, 156, 163], 'sensor.': [9], 'Activated': [10], 'following': [11], 'a': [12, 33, 104, 138], 'depletion': [13], 'of': [14, 65, 106, 121, 161], 'stores,': [17], 'AMPK': [18, 37, 51, 107, 136], 'will': [19, 39], 'restore': [20], 'homoeostasis': [23], 'by': [24, 130], 'increasing': [25], 'production': [27], 'and': [28, 45, 63, 78, 95, 155], 'limiting': [29], 'waste.': [31], 'At': [32], 'central': [34, 111], 'level,': [35], 'pathway': [38], 'integrate': [40], 'peripheral': [41, 114], 'signals': [42], '(mostly': [43], 'hormones': [44], 'metabolites)': [46], 'through': [47, 103], 'neuronal': [48], 'networks.': [49], 'Hypothalamic': [50], 'directly': [53], 'implicated': [54], 'in': [55, 73, 141, 153], 'feeding': [56, 154], 'behaviour,': [57], 'brown': [58], 'adipose': [59, 67], 'tissue': [60, 68], '(BAT)': [61], 'thermogenesis': [62], 'browning': [64], 'white': [66], '(WAT).': [69], 'It': [70], 'also': [71, 128], 'participates': [72], 'other': [74], 'metabolic': [75, 142], 'functions:': [76], 'glucose': [77], 'muscle': [79], 'metabolisms,': [80], 'as': [81, 83, 92, 125, 137, 145], 'well': [82], 'hepatic': [84], 'function.': [85], 'Numerous': [86], 'anti-obesity': [87], 'and/or': [88], 'antidiabetic': [89], 'agents,': [90], 'such': [91, 124], 'nicotine,': [93], 'metformin': [94], 'liraglutide,': [96], 'are': [97, 127], 'known': [98], 'to': [99, 150], 'induce': [100], 'their': [101], 'effects': [102, 120], 'modulation': [105], 'pathway,': [108], 'either': [109], 'at': [110, 113], 'or': [112], 'levels.': [115], 'Moreover,': [116], 'weight-gaining': [118], 'side': [119], 'antipsychotic': [122], 'drugs,': [123], 'olanzapine,': [126], 'mediated': [129], 'hypothalamic': [131, 135], 'AMPK.': [132], 'Therefore,': [133], 'considering': [134], 'therapeutic': [139], 'target': [140], 'diseases': [143], 'appears': [144], 'an': [146], 'interesting': [147], 'strategy': [148], 'due': [149], 'its': [151], 'implication': [152], 'expenditure,': [157], 'two': [159], 'sides': [160], 'balance': [164], 'equation.': [165]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2841848923', 'counts_by_year': [{'year': 2024, 'cited_by_count': 20}, {'year': 2023, 'cited_by_count': 16}, {'year': 2022, 'cited_by_count': 13}, {'year': 2021, 'cited_by_count': 16}, {'year': 2020, 'cited_by_count': 18}, {'year': 2019, 'cited_by_count': 12}], 'updated_date': '2025-01-07T21:21:04.880481', 'created_date': '2018-07-19'}