Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2810806599', 'doi': 'https://doi.org/10.1056/nejmoa1800536', 'title': 'Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer', 'display_name': 'Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer', 'publication_year': 2018, 'publication_date': '2018-06-27', 'ids': {'openalex': 'https://openalex.org/W2810806599', 'doi': 'https://doi.org/10.1056/nejmoa1800536', 'mag': '2810806599', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29949494', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8288034'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1800536', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1800536?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1800536?articleTools=true', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5041126882', 'display_name': 'Maha Hussain', 'orcid': 'https://orcid.org/0000-0003-0380-9465'}, 'institutions': [{'id': 'https://openalex.org/I4210116551', 'display_name': 'Western University', 'ror': 'https://ror.org/02agqkc58', 'country_code': 'KH', 'type': 'education', 'lineage': ['https://openalex.org/I4210116551']}], 'countries': ['KH'], 'is_corresponding': False, 'raw_author_name': 'Maha Hussain', 'raw_affiliation_strings': ['Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago'], 'affiliations': [{'raw_affiliation_string': 'Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago', 'institution_ids': ['https://openalex.org/I4210116551']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007779528', 'display_name': 'Karim Fizazi', 'orcid': 'https://orcid.org/0000-0002-6068-9474'}, 'institutions': [{'id': 'https://openalex.org/I102197404', 'display_name': 'Université Paris-Sud', 'ror': 'https://ror.org/028rypz17', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I102197404']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Karim Fizazi', 'raw_affiliation_strings': ['Institut Gustave Roussy, University of Paris Sud, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Institut Gustave Roussy, University of Paris Sud, Villejuif, France', 'institution_ids': ['https://openalex.org/I102197404', 'https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053749991', 'display_name': 'Fred Saad', 'orcid': 'https://orcid.org/0000-0003-2986-5617'}, 'institutions': [{'id': 'https://openalex.org/I70931966', 'display_name': 'Université de Montréal', 'ror': 'https://ror.org/0161xgx34', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Fred Saad', 'raw_affiliation_strings': ['University of Montreal Hospital Center, Montreal'], 'affiliations': [{'raw_affiliation_string': 'University of Montreal Hospital Center, Montreal', 'institution_ids': ['https://openalex.org/I70931966']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078934527', 'display_name': 'Per Rathenborg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801827564', 'display_name': 'Herlev Hospital', 'ror': 'https://ror.org/00wys9y90', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801827564']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Per Rathenborg', 'raw_affiliation_strings': ['Herlev Hospital, Herlev, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Herlev Hospital, Herlev, Denmark', 'institution_ids': ['https://openalex.org/I2801827564']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088518998', 'display_name': 'Neal D. Shore', 'orcid': 'https://orcid.org/0000-0001-5767-0548'}, 'institutions': [{'id': 'https://openalex.org/I4210165013', 'display_name': 'Carolina Urologic Research Center', 'ror': 'https://ror.org/05vk9vy20', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210165013']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Neal Shore', 'raw_affiliation_strings': ['Carolina Urologic Research Center, Myrtle Beach, SC'], 'affiliations': [{'raw_affiliation_string': 'Carolina Urologic Research Center, Myrtle Beach, SC', 'institution_ids': ['https://openalex.org/I4210165013']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002629084', 'display_name': 'Ubirajara Ferreira', 'orcid': 'https://orcid.org/0000-0001-6477-5153'}, 'institutions': [], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Ubirajara Ferreira', 'raw_affiliation_strings': ['Campinas, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Campinas, Brazil', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022303681', 'display_name': 'Petro Ivashchenko', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210147449', 'display_name': 'Kyiv City Clinical Oncology Center', 'ror': 'https://ror.org/0555ajd25', 'country_code': 'UA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210147449']}], 'countries': ['UA'], 'is_corresponding': False, 'raw_author_name': 'Petro Ivashchenko', 'raw_affiliation_strings': ['Kiev City Clinical Hospital 3, Kiev, Ukraine'], 'affiliations': [{'raw_affiliation_string': 'Kiev City Clinical Hospital 3, Kiev, Ukraine', 'institution_ids': ['https://openalex.org/I4210147449']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014333389', 'display_name': 'Eren Demirhan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180857899', 'display_name': 'Pfizer (United States)', 'ror': 'https://ror.org/01xdqrp08', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I180857899']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eren Demirhan', 'raw_affiliation_strings': ['Pfizer, San Francisco'], 'affiliations': [{'raw_affiliation_string': 'Pfizer, San Francisco', 'institution_ids': ['https://openalex.org/I180857899']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109393488', 'display_name': 'Katharina Modelska', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180857899', 'display_name': 'Pfizer (United States)', 'ror': 'https://ror.org/01xdqrp08', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I180857899']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Katharina Modelska', 'raw_affiliation_strings': ['Pfizer, San Francisco'], 'affiliations': [{'raw_affiliation_string': 'Pfizer, San Francisco', 'institution_ids': ['https://openalex.org/I180857899']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110020037', 'display_name': 'De Phung', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210165171', 'display_name': 'Astellas Pharma (United States)', 'ror': 'https://ror.org/05pw69n24', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I142395110', 'https://openalex.org/I4210165171']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'De Phung', 'raw_affiliation_strings': ['Astellas Pharma, Northbrook'], 'affiliations': [{'raw_affiliation_string': 'Astellas Pharma, Northbrook', 'institution_ids': ['https://openalex.org/I4210165171']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076368703', 'display_name': 'Andrew Krivoshik', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210165171', 'display_name': 'Astellas Pharma (United States)', 'ror': 'https://ror.org/05pw69n24', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I142395110', 'https://openalex.org/I4210165171']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Andrew Krivoshik', 'raw_affiliation_strings': ['Astellas Pharma, Northbrook'], 'affiliations': [{'raw_affiliation_string': 'Astellas Pharma, Northbrook', 'institution_ids': ['https://openalex.org/I4210165171']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5004985848', 'display_name': 'Cora N. Sternberg', 'orcid': 'https://orcid.org/0000-0003-3938-2627'}, 'institutions': [{'id': 'https://openalex.org/I4210134894', 'display_name': 'Nini Hospital', 'ror': 'https://ror.org/0359v5r48', 'country_code': 'LB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210134894']}], 'countries': ['LB'], 'is_corresponding': False, 'raw_author_name': 'Cora N. Sternberg', 'raw_affiliation_strings': ['Department of Medical Oncology, San Camillo Forlanini Hospital, Rome'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Oncology, San Camillo Forlanini Hospital, Rome', 'institution_ids': ['https://openalex.org/I4210134894']}]}], 'institution_assertions': [], 'countries_distinct_count': 8, 'institutions_distinct_count': 10, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 117.894, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 912, 'citation_normalized_percentile': {'value': 0.999972, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '378', 'issue': '26', 'first_page': '2465', 'last_page': '2474'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12465', 'display_name': 'Cancer, Lipids, and Metabolism', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11146', 'display_name': 'Hormonal and reproductive studies', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/enzalutamide', 'display_name': 'Enzalutamide', 'score': 0.95442647}], 'concepts': [{'id': 'https://openalex.org/C2776551883', 'wikidata': 'https://www.wikidata.org/wiki/Q1996756', 'display_name': 'Enzalutamide', 'level': 5, 'score': 0.95442647}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.85755575}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5940751}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.55431426}, {'id': 'https://openalex.org/C2779256933', 'wikidata': 'https://www.wikidata.org/wiki/Q58929', 'display_name': 'Castration', 'level': 3, 'score': 0.45644668}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.42422378}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.36857903}, {'id': 'https://openalex.org/C126894567', 'wikidata': 'https://www.wikidata.org/wiki/Q105650', 'display_name': 'Urology', 'level': 1, 'score': 0.33193874}, {'id': 'https://openalex.org/C61367390', 'wikidata': 'https://www.wikidata.org/wiki/Q416601', 'display_name': 'Androgen receptor', 'level': 4, 'score': 0.09028351}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.061633915}], 'mesh': [], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1800536', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1800536?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288034', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29949494', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1800536', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1800536?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.69, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320307765', 'funder_display_name': 'Pfizer', 'award_id': None}, {'funder': 'https://openalex.org/F4320307769', 'funder_display_name': 'Astellas Pharma US', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 17, 'referenced_works': ['https://openalex.org/W1891435709', 'https://openalex.org/W1948383940', 'https://openalex.org/W1979832268', 'https://openalex.org/W2000853346', 'https://openalex.org/W2060432974', 'https://openalex.org/W2060924022', 'https://openalex.org/W2071879495', 'https://openalex.org/W2101134619', 'https://openalex.org/W2102929728', 'https://openalex.org/W2104127658', 'https://openalex.org/W2119504728', 'https://openalex.org/W2148643283', 'https://openalex.org/W2150402649', 'https://openalex.org/W2166918329', 'https://openalex.org/W2239698670', 'https://openalex.org/W2252849995', 'https://openalex.org/W2743350540'], 'related_works': ['https://openalex.org/W4361842353', 'https://openalex.org/W4214808211', 'https://openalex.org/W3122236002', 'https://openalex.org/W3024577600', 'https://openalex.org/W3023935924', 'https://openalex.org/W2931472946', 'https://openalex.org/W2773216890', 'https://openalex.org/W2681186693', 'https://openalex.org/W2593283143', 'https://openalex.org/W2479406918'], 'abstract_inverted_index': {'Men': [0], 'with': [1, 30, 40, 64, 158, 212, 216, 296, 303, 308, 336], 'nonmetastatic,': [2, 41, 65, 304], 'castration-resistant': [3, 32, 42, 66, 305], 'prostate': [4, 33, 43, 67, 306], 'cancer': [5, 44, 68, 307], 'and': [6, 45, 69, 272, 321, 346], 'a': [7, 46, 60, 70, 88, 139, 206, 309, 318], 'rapidly': [8, 47, 310], 'rising': [9, 48, 311], 'prostate-specific': [10], 'antigen': [11], '(PSA)': [12], 'level': [13], 'are': [14], 'at': [15], 'high': [16], 'risk': [17, 325], 'for': [18, 187], 'metastasis.': [19], 'We': [20], 'hypothesized': [21], 'that': [22], 'enzalutamide,': [23, 293], 'which': [24], 'prolongs': [25], 'overall': [26, 265], 'survival': [27, 103, 170], 'among': [28], 'patients': [29, 125, 145, 268, 291], 'metastatic,': [31], 'cancer,': [34], 'would': [35], 'delay': [36], 'metastasis': [37, 152, 188, 327], 'in': [38, 59, 147, 163, 174, 181, 230, 253, 287], 'men': [39, 63, 302], 'PSA': [49, 71, 127, 241, 312], 'level.In': [50], 'this': [51], 'double-blind,': [52], 'phase': [53], '3': [54, 283], 'trial,': [55], 'we': [56], 'randomly': [57], 'assigned,': [58], '2:1': [61], 'ratio,': [62, 223, 248], 'doubling': [72, 128], 'time': [73, 107, 116, 200, 239], 'of': [74, 90, 123, 135, 141, 143, 160, 205, 234, 257, 264, 281, 289, 298, 326, 341], '10': [75], 'months': [76, 173, 180], 'or': [77, 93, 113, 153, 189, 284, 328], 'less': [78], 'who': [79], 'were': [80, 334], 'continuing': [81], 'androgen-deprivation': [82], 'therapy': [83, 209, 227], 'to': [84, 110, 117, 196, 201, 240, 317], 'receive': [85], 'enzalutamide': [86, 149, 176, 213, 271, 314], '(at': [87], 'dose': [89], '160': [91], 'mg)': [92], 'placebo': [94, 165, 183, 217, 276], 'once': [95], 'daily.': [96], 'The': [97, 167, 199], 'primary': [98], 'end': [99], 'point': [100], 'was': [101, 171, 210, 228, 237], 'metastasis-free': [102, 169], '(defined': [104], 'as': [105, 114, 156, 236, 294], 'the': [106, 115, 148, 164, 175, 182, 202, 238, 260, 290, 337], 'from': [108], 'randomization': [109], 'radiographic': [111, 120], 'progression': [112, 242, 251], 'death': [118, 329], 'without': [119], 'progression).A': [121], 'total': [122, 140], '1401': [124], '(median': [126], 'time,': [129], '3.7': [130], 'months)': [131], 'underwent': [132], 'randomization.': [133], 'As': [134], 'June': [136], '28,': [137], '2017,': [138], '219': [142], '933': [144], '(23%)': [146], 'group': [150, 177, 184], 'had': [151, 154, 277], 'died,': [155], 'compared': [157, 295], '228': [159], '468': [161], '(49%)': [162], 'group.': [166], 'median': [168], '36.6': [172], 'versus': [178], '14.7': [179], '(hazard': [185], 'ratio': [186], 'death,': [190], '0.29;': [191], '95%': [192], 'confidence': [193], 'interval,': [194], '0.24': [195], '0.35;': [197], 'P<0.001).': [198], 'first': [203, 261], 'use': [204], 'subsequent': [207], 'antineoplastic': [208], 'longer': [211], 'treatment': [214, 315], 'than': [215, 330], '(39.6': [218], 'vs.': [219, 232, 244, 255], '17.7': [220], 'months;': [221, 246], 'hazard': [222, 247], '0.21;': [224], 'P<0.001;': [225, 250], 'such': [226], 'used': [229], '15%': [231], '48%': [233], 'patients)': [235], '(37.2': [243], '3.9': [245], '0.07;': [249], 'occurred': [252, 286], '22%': [254], '69%': [256], 'patients).': [258], 'At': [259], 'interim': [262], 'analysis': [263], 'survival,': [266], '103': [267], '(11%)': [269], 'receiving': [270, 275, 292, 300], '62': [273], '(13%)': [274], 'died.': [278], 'Adverse': [279, 332], 'events': [280, 333], 'grade': [282], 'higher': [285], '31%': [288], '23%': [297], 'those': [299], 'placebo.Among': [301], 'level,': [313], 'led': [316], 'clinically': [319], 'meaningful': [320], 'significant': [322], '71%': [323], 'lower': [324], 'placebo.': [331], 'consistent': [335], 'established': [338], 'safety': [339], 'profile': [340], 'enzalutamide.': [342], '(Funded': [343], 'by': [344], 'Pfizer': [345], 'Astellas': [347], 'Pharma;': [348], 'PROSPER': [349], 'ClinicalTrials.gov': [350], 'number,': [351], 'NCT02003924': [352], '.).': [353]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2810806599', 'counts_by_year': [{'year': 2024, 'cited_by_count': 92}, {'year': 2023, 'cited_by_count': 114}, {'year': 2022, 'cited_by_count': 113}, {'year': 2021, 'cited_by_count': 200}, {'year': 2020, 'cited_by_count': 189}, {'year': 2019, 'cited_by_count': 160}, {'year': 2018, 'cited_by_count': 40}, {'year': 2017, 'cited_by_count': 2}], 'updated_date': '2024-12-09T12:11:06.428266', 'created_date': '2018-07-10'}