Sudden cardiac death in J wave syndrome with short QT associated to a novel mutation in Nav 1.8 coding gene SCN10A: First case report for a possible pharmacogenomic role

Name: Work Video:
Duration: 3 min 30 s
Giuseppe Di Stolfo; Pietro Palumbo; Stefano Castellana; Sandra Mastroianno; Tommaso Biagini; Orazio Palumbo; Maria Pia Leone; Giovanni De Luca; Domenico Potenza; Tommaso Mazza; Aldo Russo; Massimo Carella
{'id': 'https://openalex.org/W2807010560', 'doi': 'https://doi.org/10.1016/j.jelectrocard.2018.06.005', 'title': 'Sudden cardiac death in J wave syndrome with short QT associated to a novel mutation in Nav 1.8 coding gene SCN10A: First case report for a possible pharmacogenomic role', 'display_name': 'Sudden cardiac death in J wave syndrome with short QT associated to a novel mutation in Nav 1.8 coding gene SCN10A: First case report for a possible pharmacogenomic role', 'publication_year': 2018, 'publication_date': '2018-06-09', 'ids': {'openalex': 'https://openalex.org/W2807010560', 'doi': 'https://doi.org/10.1016/j.jelectrocard.2018.06.005', 'mag': '2807010560', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/30177317'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.jelectrocard.2018.06.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S197069552', 'display_name': 'Journal of Electrocardiology', 'issn_l': '0022-0736', 'issn': ['0022-0736', '1532-8430'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076189244', 'display_name': 'Giuseppe Di Stolfo', 'orcid': 'https://orcid.org/0000-0003-1758-7138'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Giuseppe Di Stolfo', 'raw_affiliation_strings': ['Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013226469', 'display_name': 'Pietro Palumbo', 'orcid': 'https://orcid.org/0000-0001-9498-9902'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Pietro Palumbo', 'raw_affiliation_strings': ['Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051511165', 'display_name': 'Stefano Castellana', 'orcid': 'https://orcid.org/0000-0001-8688-9530'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Stefano Castellana', 'raw_affiliation_strings': ['Bioinformatics Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Bioinformatics Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045025946', 'display_name': 'Sandra Mastroianno', 'orcid': 'https://orcid.org/0000-0001-6898-4657'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Sandra Mastroianno', 'raw_affiliation_strings': ['Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022257092', 'display_name': 'Tommaso Biagini', 'orcid': 'https://orcid.org/0000-0002-4539-028X'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Tommaso Biagini', 'raw_affiliation_strings': ['Bioinformatics Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Bioinformatics Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001811933', 'display_name': 'Orazio Palumbo', 'orcid': 'https://orcid.org/0000-0001-6583-3482'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Orazio Palumbo', 'raw_affiliation_strings': ['Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057724055', 'display_name': 'Maria Pia Leone', 'orcid': 'https://orcid.org/0000-0003-3182-4494'}, 'institutions': [{'id': 'https://openalex.org/I5561750', 'display_name': 'University of Bari Aldo Moro', 'ror': 'https://ror.org/027ynra39', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I5561750']}, {'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Maria Pia Leone', 'raw_affiliation_strings': ['Department of Soil, Plant and Food Science, University of Bari "Aldo Moro", Via Amendola 165/A, 70126 Bari, Italy', 'Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Soil, Plant and Food Science, University of Bari "Aldo Moro", Via Amendola 165/A, 70126 Bari, Italy', 'institution_ids': ['https://openalex.org/I5561750']}, {'raw_affiliation_string': 'Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051544275', 'display_name': 'Giovanni De Luca', 'orcid': 'https://orcid.org/0000-0001-9463-006X'}, 'institutions': [{'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Giovanni De Luca', 'raw_affiliation_strings': ['Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I4210153126', 'https://openalex.org/I2800188116']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110585645', 'display_name': 'Domenico Potenza', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Domenico Rosario Potenza', 'raw_affiliation_strings': ['Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076382228', 'display_name': 'Tommaso Mazza', 'orcid': 'https://orcid.org/0000-0003-0434-8533'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Tommaso Mazza', 'raw_affiliation_strings': ['Bioinformatics Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Bioinformatics Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102306218', 'display_name': 'Aldo Russo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}, {'id': 'https://openalex.org/I4210153126', 'display_name': 'Istituti di Ricovero e Cura a Carattere Scientifico', 'ror': 'https://ror.org/04tfzc498', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Aldo A. Russo', 'raw_affiliation_strings': ['Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Department, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5036893941', 'display_name': 'Massimo Carella', 'orcid': 'https://orcid.org/0000-0002-6830-6829'}, 'institutions': [{'id': 'https://openalex.org/I2800188116', 'display_name': 'Casa Sollievo della Sofferenza', 'ror': 'https://ror.org/00md77g41', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800188116', 'https://openalex.org/I4210153126']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Massimo Carella', 'raw_affiliation_strings': ['Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Genetics, Poliambulatorio "Giovanni Paolo II", IRCCS Casa Sollievo della Sofferenza, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy', 'institution_ids': ['https://openalex.org/I2800188116']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5036893941'], 'corresponding_institution_ids': ['https://openalex.org/I2800188116'], 'apc_list': {'value': 2910, 'currency': 'USD', 'value_usd': 2910, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.487, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.821904, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '51', 'issue': '5', 'first_page': '809', 'last_page': '813'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11217', 'display_name': 'Cardiac Arrhythmias and Treatments', 'score': 0.9863, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pharmacogenomics', 'display_name': 'Pharmacogenomics', 'score': 0.73104334}, {'id': 'https://openalex.org/keywords/coding-region', 'display_name': 'Coding region', 'score': 0.43261716}, {'id': 'https://openalex.org/keywords/sudden-death', 'display_name': 'Sudden Death', 'score': 0.41609997}], 'concepts': [{'id': 'https://openalex.org/C170734499', 'wikidata': 'https://www.wikidata.org/wiki/Q1152227', 'display_name': 'Pharmacogenomics', 'level': 2, 'score': 0.73104334}, {'id': 'https://openalex.org/C2779703243', 'wikidata': 'https://www.wikidata.org/wiki/Q653924', 'display_name': 'Long QT syndrome', 'level': 3, 'score': 0.7005244}, {'id': 'https://openalex.org/C2775935837', 'wikidata': 'https://www.wikidata.org/wiki/Q202837', 'display_name': 'Sudden cardiac death', 'level': 2, 'score': 0.6471931}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.4543256}, {'id': 'https://openalex.org/C91779695', 'wikidata': 'https://www.wikidata.org/wiki/Q3780824', 'display_name': 'Coding region', 'level': 3, 'score': 0.43261716}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.42406702}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.42141348}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.4209485}, {'id': 'https://openalex.org/C2993353509', 'wikidata': 'https://www.wikidata.org/wiki/Q411867', 'display_name': 'Sudden death', 'level': 2, 'score': 0.41609997}, {'id': 'https://openalex.org/C118441451', 'wikidata': 'https://www.wikidata.org/wiki/Q12074763', 'display_name': 'QT interval', 'level': 2, 'score': 0.4076864}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.321329}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.31854892}], 'mesh': [{'descriptor_ui': 'D001145', 'descriptor_name': 'Arrhythmias, Cardiac', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016757', 'descriptor_name': 'Death, Sudden, Cardiac', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D020125', 'descriptor_name': 'Mutation, Missense', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D062559', 'descriptor_name': 'NAV1.8 Voltage-Gated Sodium Channel', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001145', 'descriptor_name': 'Arrhythmias, Cardiac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001145', 'descriptor_name': 'Arrhythmias, Cardiac', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D052246', 'descriptor_name': 'Cyclooxygenase 2 Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052246', 'descriptor_name': 'Cyclooxygenase 2 Inhibitors', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D016757', 'descriptor_name': 'Death, Sudden, Cardiac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004562', 'descriptor_name': 'Electrocardiography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077613', 'descriptor_name': 'Etoricoxib', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077613', 'descriptor_name': 'Etoricoxib', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020022', 'descriptor_name': 'Genetic Predisposition to Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062559', 'descriptor_name': 'NAV1.8 Voltage-Gated Sodium Channel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062559', 'descriptor_name': 'NAV1.8 Voltage-Gated Sodium Channel', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D011487', 'descriptor_name': 'Protein Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.jelectrocard.2018.06.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S197069552', 'display_name': 'Journal of Electrocardiology', 'issn_l': '0022-0736', 'issn': ['0022-0736', '1532-8430'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/30177317', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.88, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320322836', 'funder_display_name': 'Ministry of Health, British Columbia', 'award_id': 'RC1701CA12'}], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1983886037', 'https://openalex.org/W1984068087', 'https://openalex.org/W1998634339', 'https://openalex.org/W2001162433', 'https://openalex.org/W2015904128', 'https://openalex.org/W2030097304', 'https://openalex.org/W2046060396', 'https://openalex.org/W2101412130', 'https://openalex.org/W2118055036', 'https://openalex.org/W2119180969', 'https://openalex.org/W2121320489', 'https://openalex.org/W2122732537', 'https://openalex.org/W2126196113', 'https://openalex.org/W2131237335', 'https://openalex.org/W2136755991', 'https://openalex.org/W2146481951', 'https://openalex.org/W2154866190', 'https://openalex.org/W2160018263', 'https://openalex.org/W2166950143', 'https://openalex.org/W2170551349', 'https://openalex.org/W2256016639', 'https://openalex.org/W2413551548', 'https://openalex.org/W2464776507', 'https://openalex.org/W2511515754', 'https://openalex.org/W2598967640', 'https://openalex.org/W2599761051', 'https://openalex.org/W2605416319', 'https://openalex.org/W2619830777'], 'related_works': ['https://openalex.org/W4255707928', 'https://openalex.org/W4237478000', 'https://openalex.org/W3106754853', 'https://openalex.org/W2893229475', 'https://openalex.org/W2526452705', 'https://openalex.org/W2133442649', 'https://openalex.org/W2092950144', 'https://openalex.org/W2062288119', 'https://openalex.org/W2060105258', 'https://openalex.org/W2033888008'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2807010560', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 2}], 'updated_date': '2024-12-16T09:42:21.899217', 'created_date': '2018-06-13'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
