Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome: A Comprehensive Review

Name: Work Video:
Duration: 3 min 30 s
Eleftherios M. Kallergis; Christos A. Goudis; Εmmanuel Simantirakis; George Kochiadakis; Panos Vardas
{'id': 'https://openalex.org/W2060105258', 'doi': 'https://doi.org/10.1100/2012/212178', 'title': 'Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome: A Comprehensive Review', 'display_name': 'Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome: A Comprehensive Review', 'publication_year': 2012, 'publication_date': '2012-01-01', 'ids': {'openalex': 'https://openalex.org/W2060105258', 'doi': 'https://doi.org/10.1100/2012/212178', 'mag': '2060105258', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22593664', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3347892'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1100/2012/212178', 'pdf_url': 'https://downloads.hindawi.com/journals/tswj/2012/212178.pdf', 'source': {'id': 'https://openalex.org/S29243050', 'display_name': 'The Scientific World JOURNAL', 'issn_l': '1537-744X', 'issn': ['1537-744X', '2356-6140'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://downloads.hindawi.com/journals/tswj/2012/212178.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108831356', 'display_name': 'Eleftherios M. Kallergis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210138654', 'display_name': 'University Hospital of Heraklion', 'ror': 'https://ror.org/0312m2266', 'country_code': 'GR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210138654']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Eleftherios M. Kallergis', 'raw_affiliation_strings': ['Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.', 'institution_ids': ['https://openalex.org/I4210138654']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026137541', 'display_name': 'Christos A. Goudis', 'orcid': 'https://orcid.org/0000-0003-4476-2640'}, 'institutions': [{'id': 'https://openalex.org/I4210138654', 'display_name': 'University Hospital of Heraklion', 'ror': 'https://ror.org/0312m2266', 'country_code': 'GR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210138654']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Christos A. Goudis', 'raw_affiliation_strings': ['Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.', 'institution_ids': ['https://openalex.org/I4210138654']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035641722', 'display_name': 'Εmmanuel Simantirakis', 'orcid': 'https://orcid.org/0000-0001-9615-6293'}, 'institutions': [{'id': 'https://openalex.org/I4210138654', 'display_name': 'University Hospital of Heraklion', 'ror': 'https://ror.org/0312m2266', 'country_code': 'GR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210138654']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Emmanuel N. Simantirakis', 'raw_affiliation_strings': ['Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.', 'institution_ids': ['https://openalex.org/I4210138654']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090825972', 'display_name': 'George Kochiadakis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210138654', 'display_name': 'University Hospital of Heraklion', 'ror': 'https://ror.org/0312m2266', 'country_code': 'GR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210138654']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'George E. Kochiadakis', 'raw_affiliation_strings': ['Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.', 'institution_ids': ['https://openalex.org/I4210138654']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5082310755', 'display_name': 'Panos Vardas', 'orcid': 'https://orcid.org/0000-0002-4499-0806'}, 'institutions': [{'id': 'https://openalex.org/I4210138654', 'display_name': 'University Hospital of Heraklion', 'ror': 'https://ror.org/0312m2266', 'country_code': 'GR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210138654']}], 'countries': ['GR'], 'is_corresponding': False, 'raw_author_name': 'Panos E. Vardas', 'raw_affiliation_strings': ['Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, University Hospital of Heraklion, 711 10 Heraklion, Crete, Greece.', 'institution_ids': ['https://openalex.org/I4210138654']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 775, 'currency': 'USD', 'value_usd': 775, 'provenance': 'doaj'}, 'apc_paid': {'value': 775, 'currency': 'USD', 'value_usd': 775, 'provenance': 'doaj'}, 'fwci': 2.194, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 175, 'citation_normalized_percentile': {'value': 0.999298, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '2012', 'issue': None, 'first_page': '1', 'last_page': '8'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9888, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/torsades-de-pointes', 'display_name': 'Torsades de pointes', 'score': 0.8832216}, {'id': 'https://openalex.org/keywords/stressor', 'display_name': 'Stressor', 'score': 0.5893425}], 'concepts': [{'id': 'https://openalex.org/C118441451', 'wikidata': 'https://www.wikidata.org/wiki/Q12074763', 'display_name': 'QT interval', 'level': 2, 'score': 0.89365816}, {'id': 'https://openalex.org/C2780486423', 'wikidata': 'https://www.wikidata.org/wiki/Q1625433', 'display_name': 'Torsades de pointes', 'level': 3, 'score': 0.8832216}, {'id': 'https://openalex.org/C2779703243', 'wikidata': 'https://www.wikidata.org/wiki/Q653924', 'display_name': 'Long QT syndrome', 'level': 3, 'score': 0.83218205}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.76325583}, {'id': 'https://openalex.org/C125370674', 'wikidata': 'https://www.wikidata.org/wiki/Q1527480', 'display_name': 'Stressor', 'level': 2, 'score': 0.5893425}, {'id': 'https://openalex.org/C2776331378', 'wikidata': 'https://www.wikidata.org/wiki/Q56002', 'display_name': 'Ventricular tachycardia', 'level': 2, 'score': 0.57511246}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.47788823}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.45778906}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.45197248}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.4361356}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.104159}], 'mesh': [{'descriptor_ui': 'D008133', 'descriptor_name': 'Long QT Syndrome', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D008133', 'descriptor_name': 'Long QT Syndrome', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D064420', 'descriptor_name': 'Drug-Related Side Effects and Adverse Reactions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004562', 'descriptor_name': 'Electrocardiography', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004562', 'descriptor_name': 'Electrocardiography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008133', 'descriptor_name': 'Long QT Syndrome', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D008133', 'descriptor_name': 'Long QT Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012737', 'descriptor_name': 'Sex Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016171', 'descriptor_name': 'Torsades de Pointes', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D016171', 'descriptor_name': 'Torsades de Pointes', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D016171', 'descriptor_name': 'Torsades de Pointes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1100/2012/212178', 'pdf_url': 'https://downloads.hindawi.com/journals/tswj/2012/212178.pdf', 'source': {'id': 'https://openalex.org/S29243050', 'display_name': 'The Scientific World JOURNAL', 'issn_l': '1537-744X', 'issn': ['1537-744X', '2356-6140'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3347892', 'pdf_url': 'https://europepmc.org/articles/pmc3347892?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347892', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22593664', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1100/2012/212178', 'pdf_url': 'https://downloads.hindawi.com/journals/tswj/2012/212178.pdf', 'source': {'id': 'https://openalex.org/S29243050', 'display_name': 'The Scientific World JOURNAL', 'issn_l': '1537-744X', 'issn': ['1537-744X', '2356-6140'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.82, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 85, 'referenced_works': ['https://openalex.org/W1232760234', 'https://openalex.org/W1575292282', 'https://openalex.org/W1586405772', 'https://openalex.org/W160020775', 'https://openalex.org/W1964127609', 'https://openalex.org/W1966064887', 'https://openalex.org/W1968371524', 'https://openalex.org/W1970365812', 'https://openalex.org/W1970677226', 'https://openalex.org/W1970935084', 'https://openalex.org/W1975869151', 'https://openalex.org/W1976618595', 'https://openalex.org/W1979924020', 'https://openalex.org/W1980240868', 'https://openalex.org/W1980496173', 'https://openalex.org/W1983137097', 'https://openalex.org/W1991053107', 'https://openalex.org/W1991902077', 'https://openalex.org/W1996802734', 'https://openalex.org/W2001537992', 'https://openalex.org/W2002422701', 'https://openalex.org/W2002711428', 'https://openalex.org/W2002737978', 'https://openalex.org/W2005411701', 'https://openalex.org/W2006964534', 'https://openalex.org/W2007042571', 'https://openalex.org/W2008125074', 'https://openalex.org/W2009915447', 'https://openalex.org/W2017943224', 'https://openalex.org/W2017943675', 'https://openalex.org/W2017951998', 'https://openalex.org/W2018841001', 'https://openalex.org/W2019079248', 'https://openalex.org/W2026068418', 'https://openalex.org/W2026281747', 'https://openalex.org/W2027433270', 'https://openalex.org/W2032748950', 'https://openalex.org/W2034369347', 'https://openalex.org/W2035257119', 'https://openalex.org/W2036215895', 'https://openalex.org/W2037921660', 'https://openalex.org/W2039123964', 'https://openalex.org/W2040826404', 'https://openalex.org/W2048688147', 'https://openalex.org/W2057406399', 'https://openalex.org/W2058526985', 'https://openalex.org/W2061060474', 'https://openalex.org/W2066742955', 'https://openalex.org/W2067418531', 'https://openalex.org/W2072797200', 'https://openalex.org/W2074093573', 'https://openalex.org/W2074705578', 'https://openalex.org/W2074901227', 'https://openalex.org/W2081517567', 'https://openalex.org/W2081681752', 'https://openalex.org/W2082275497', 'https://openalex.org/W2082626069', 'https://openalex.org/W2089412560', 'https://openalex.org/W2091425082', 'https://openalex.org/W2092950144', 'https://openalex.org/W2093784373', 'https://openalex.org/W2094886506', 'https://openalex.org/W2099086672', 'https://openalex.org/W2100136790', 'https://openalex.org/W2116581628', 'https://openalex.org/W2119089995', 'https://openalex.org/W2126236636', 'https://openalex.org/W2127815448', 'https://openalex.org/W2128940750', 'https://openalex.org/W2134569467', 'https://openalex.org/W2145137957', 'https://openalex.org/W2147857057', 'https://openalex.org/W2150629896', 'https://openalex.org/W2150745003', 'https://openalex.org/W2152136740', 'https://openalex.org/W2158987251', 'https://openalex.org/W2165140743', 'https://openalex.org/W2168806904', 'https://openalex.org/W2314139393', 'https://openalex.org/W2346804189', 'https://openalex.org/W2394528711', 'https://openalex.org/W2397955460', 'https://openalex.org/W2408310262', 'https://openalex.org/W2482262205', 'https://openalex.org/W2594804082'], 'related_works': ['https://openalex.org/W4307172607', 'https://openalex.org/W3023690577', 'https://openalex.org/W2409143881', 'https://openalex.org/W2125645277', 'https://openalex.org/W2094120230', 'https://openalex.org/W2087234566', 'https://openalex.org/W2060105258', 'https://openalex.org/W1997214226', 'https://openalex.org/W1968550939', 'https://openalex.org/W1605055936'], 'abstract_inverted_index': {'Long': [0], 'QT': [1, 10, 38, 46, 72, 79, 136, 154], 'syndrome': [2, 39, 73, 80], 'is': [3, 18, 74, 81], 'characterized': [4], 'by': [5], 'prolongation': [6, 43], 'of': [7, 22, 44, 61, 97, 111, 151], 'the': [8, 14, 45, 62, 94, 108, 122, 146], 'corrected': [9], '(QTc)': [11], 'interval': [12], 'on': [13, 133], 'surface': [15], 'electrocardiogram': [16], 'and': [17, 87, 117, 144, 148], 'associated': [19], 'with': [20, 54, 99, 103], 'precipitation': [21], 'torsade': [23], 'de': [24, 142], 'pointes': [25, 143], '(TdP),': [26], 'a': [27, 88, 104, 125], 'polymorphic': [28], 'ventricular': [29], 'tachycardia': [30], 'that': [31], 'may': [32], 'cause': [33], 'sudden': [34], 'death.': [35], 'Acquired': [36, 77], 'long': [37, 71, 78, 153], 'describes': [40], 'pathologic': [41], 'excessive': [42], 'interval,': [47], 'upon': [48], 'exposure': [49], 'to': [50, 57, 114, 120], 'an': [51, 82], 'environmental': [52, 67], 'stressor,': [53], 'reversion': [55], 'back': [56], 'normal': [58], 'following': [59], 'removal': [60], 'stressor.': [63], 'The': [64], 'most': [65], 'common': [66], 'stressor': [68], 'in': [69], 'acquired': [70, 152], 'drug': [75], 'therapy.': [76], 'important': [83], 'issue': [84], 'for': [85, 124, 140], 'clinicians': [86], 'significant': [89], 'public': [90], 'health': [91], 'problem': [92], 'concerning': [93], 'large': [95, 109], 'number': [96, 110], 'drugs': [98], 'this': [100, 129], 'adverse': [101], 'effect': [102], 'potentially': [105], 'fatal': [106], 'outcome,': [107], 'patients': [112], 'exposed': [113], 'these': [115], 'drugs,': [116], 'our': [118], 'inability': [119], 'predict': [121], 'risk': [123, 138], 'given': [126], 'individual.': [127], 'In': [128], 'paper,': [130], 'we': [131], 'focus': [132], 'mechanisms': [134], 'underlying': [135], 'prolongation,': [137], 'factors': [139], 'torsades': [141], 'describe': [145], 'short-': [147], 'long-term': [149], 'treatment': [150], 'syndrome.': [155]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2060105258', 'counts_by_year': [{'year': 2024, 'cited_by_count': 22}, {'year': 2023, 'cited_by_count': 19}, {'year': 2022, 'cited_by_count': 15}, {'year': 2021, 'cited_by_count': 18}, {'year': 2020, 'cited_by_count': 19}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 12}, {'year': 2017, 'cited_by_count': 11}, {'year': 2016, 'cited_by_count': 12}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-14T03:20:16.618661', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
