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2399, 2898], 'GreenCynthia': [144], 'Green': [146, 1793, 2423, 2900], 'Biostatistics': [149], 'Bioinformatics': [151], '(C.L.G.)': [152], 'HernandezAdrian': [156], 'Hernandez': [158, 1282, 1737, 1805, 2159, 2429, 2916, 2967], 'PatelManesh': [172], 'Patel': [174, 1340, 1733, 1783, 1799, 1902, 1928, 2403, 2432, 2919, 2970], '2400': [188, 1271], 'Pratt': [189, 1272], 'Street,': [190, 1273], 'NC': [192, 1275], '27705.': [193, 1276], 'E-mail': [194, 195, 1277], 'Address:': [196], '[email': [197], 'protected]': [198], 'Originally': [209, 3014], 'published1': [210], 'Jan': [211], '2018https://doi.org/10.1161/CIRCULATIONAHA.118.035260Circulation.': [212], '2018;138:951–953Other': [213], 'version(s)': [214], 'this': [216, 225, 993, 1172], 'articleYou': [217], 'are': [218, 1087], 'viewing': [219], 'the': [220, 240, 260, 280, 299, 303, 324, 330, 340, 373, 388, 394, 446, 499, 536, 547, 552, 568, 573, 594, 659, 857, 860, 935, 973, 990, 1003, 1014, 1064, 1074, 1089, 1107, 1110, 1123, 1145, 1151, 1248, 1252, 1256, 1291, 1317, 1345, 1467, 1515, 1602, 1639, 1691, 1697, 1860, 2007, 2185, 2481, 2505, 2809, 2874, 2879], 'most': [221], 'recent': [222], 'version': [223], 'article.': [226], 'Previous': [227, 1398], 'versions:': [228], 'January': [229], '1,': [230, 3016], '2018:': [231], 'Ahead': [232], 'Print': [234], 'The': [235, 319, 441, 661, 977, 1008, 1054, 1221, 1230, 2068, 2860, 2986], 'abdominal': [236, 249, 300], 'vascular': [237, 250, 281, 638, 823, 948, 955, 1047, 1052, 1056, 1097, 1125], 'compartment': [238, 301, 305, 326, 1057], 'is': [239, 285, 1159, 1167, 1180], 'main': [241], 'storage': [242], 'intravascular': [244], 'blood': [245, 1104], 'volume,': [246], 'decreased': [248, 286, 798, 825], 'capacitance': [251, 282, 1367], 'has': [252], 'been': [253, 1117], 'proposed': [254], 'as': [255, 273, 343, 694, 719, 940, 942, 1320, 2105], 'a': [256, 274, 277, 344, 381, 384, 482, 542, 620, 687, 712, 768, 918, 943, 998, 1019, 1027, 1042, 1060, 1092, 1101, 1164, 1168, 1321, 2045, 2340, 2574, 2623, 2870], 'major': [257, 1169], 'contributor': [258], 'complex': [261], 'pathophysiology': [262], 'heart': [264, 356, 363, 544, 1294, 1551, 1700, 1759, 2011, 2272, 2338, 2538, 2690, 2865, 2928, 3019], 'failure': [265, 1552, 1701, 2273, 2539, 2691, 2866], '(HF)': [266], 'in': [267, 294, 355, 362, 425, 551, 572, 593, 676, 711, 767, 770, 868, 921, 946, 970, 1026, 1030, 1036, 1045, 1063, 1067, 1073, 1290, 1313, 1369, 1462, 1550, 1596, 1638, 1758, 1818, 1822, 1851, 1879, 1945, 1976, 2006, 2168, 2231, 2245, 2271, 2297, 2337, 2487, 2508, 2514, 2661, 2693, 2735, 2808, 2864, 2980], 'animals': [268], 'humans.1,2': [270], 'In': [271], 'HF,': [272, 1071], 'result': [275, 293, 1090], 'neurohormonal': [278], 'imbalance,': [279], '(storage': [283], 'space)': [284], 'acute': [288, 295, 467, 682, 861, 968, 1006, 1068, 1154, 2010], 'sympathetic': [289, 320, 331, 1016], 'nerve': [290, 353, 367, 375, 396, 501, 1023, 1351, 1695, 1756, 2923, 3021], 'activation': [291], 'can': [292], 'volume': [296, 1065, 1105, 1288], 'redistribution3': [297], 'from': [298, 329, 431, 734, 775, 799, 826, 957, 985, 1106, 2300, 2873], 'thoracic': [304, 332], '(heart': [306], 'lungs),': [308], 'which': [309, 1010], 'increases': [310, 1077], 'intracardiac': [311, 716, 1031], 'pressures': [312, 590, 717, 723, 1033], 'precipitates': [314], 'HF': [315, 468, 685, 1158], 'symptoms': [316, 871, 971], '(Figure': [317, 579, 729, 938, 975], 'A).': [318], 'nervous': [321], 'system': [322], 'controls': [323], 'splanchnic': [325, 341, 374, 395, 500, 1015, 1055, 1094, 1124, 1350, 1694], 'via': [327], 'branches': [328], 'ganglia': [333], '(T6': [334], 'through': [335, 1018], 'T11).4': [336], 'We': [337], 'have': [338, 481, 1116], 'identified': [339], 'nerves': [342], 'potential': [345, 1183], 'target': [346], 'treating': [348], 'HF.Download': [349], 'figureDownload': [350], 'PowerPointFigure.': [351], 'Splanchnic': [352, 366, 1387, 1755, 1813, 1848, 2435, 2469, 2571, 2772, 2922], 'block': [354, 368, 376, 397, 502, 2611, 2924], 'failure.A,': [357], 'Concept': [358], 'fluid': [360, 1081], 'redistribution': [361, 1102, 1289, 1315], 'failure.': [364], 'B,': [365, 1439, 1742, 1788, 2028, 2156, 2414, 2598], 'procedure.': [369], 'C,': [370, 1305, 1488, 1794, 1800, 2404, 2424, 2459, 2559, 2722, 2901, 2966], 'Effects': [371], 'on': [377, 398, 494, 564], 'hemodynamics.': [378], '*': [379], 'indicates': [380, 414], 'P<0.05': [382, 406], 'pairwise': [385, 648], 'comparison': [386], 'with': [387, 469, 619, 686, 1132, 1553, 1702, 2267, 2274, 2540, 2695, 2740, 2867], 'baseline': [389, 537, 743, 759, 783, 807, 833, 879], 'value.': [390], 'D,': [391, 1437, 1480, 1527, 1663, 1726, 1921, 1931, 2251, 2327, 2422, 2913], 'Effect': [392], 'laboratory': [399], 'functional': [401], 'outcomes.': [402], 'For': [403], 'Likert': [404, 530], 'scale,': [405], 'minute': [408, 890], '90': [409, 617, 762, 789], '24': [411], 'hours.': [412, 707], 'CI': [413], 'confidence': [415, 738], 'interval;': [416], 'PRO': [418], 'BNP,': [419], 'pro-B-type': [420, 513, 924], 'natriuretic': [421, 514, 925], 'peptide.Patients': [422], 'were': [423, 478, 506, 586, 591, 623, 669, 703, 878, 901, 1130], 'enrolled': [424], 'an': [426, 952, 967], 'approved': [427, 444], 'protocol': [428, 442], '(ClinicalTrials.gov:': [429], 'NCT02669407)': [430], 'April': [432], 'November': [434], '2017': [435], 'at': [436, 567, 742, 751, 761, 782, 788, 806, 816, 832, 841, 848, 2343, 2626], 'Medical': [439], 'Center.': [440], 'was': [443, 642, 664, 674, 982, 1189], 'by': [445, 556, 696, 1041, 1119, 1191, 1254, 1373, 2569, 2617], 'Institutional': [447], 'Review': [448], 'Board,': [449], 'all': [451, 504, 539], 'patients': [452, 461, 505, 540, 657, 668, 680, 965, 2694], 'provided': [453], 'written': [454], 'informed': [455], 'consent.': [456], 'To': [457], 'qualify': [458], 'enrollment,': [460], 'had': [462, 681], 'be': [464, 1059, 1238], 'admitted': [465], 'New': [470], 'York': [471], 'Association': [473, 1194, 1204, 2739, 2877], 'class': [474], 'III/IV': [475], 'symptoms.': [476], 'Patients': [477, 1908, 1946, 2235], 'required': [479], 'pulmonary': [483, 627, 630, 721, 725], 'capillary': [484, 631, 726], 'wedge': [485, 632, 727], 'pressure': [486, 728, 774, 797], '>15': [487], 'mm': [488, 491, 777, 786, 801, 810], 'Hg': [489, 492, 778, 787, 802, 811], '(>12': [490], 'if': [493], 'inotropes).Before': [495], 'immediately': [497, 986], 'after': [498, 819, 851, 872, 934, 989, 2622], '(SNB),': [503], 'tested': [507, 997], 'catecholamine': [509], 'levels': [510, 900, 927], 'N-terminal': [512, 923], 'peptide': [515, 926], 'levels,': [516], 'transthoracic': [517, 697], 'echocardiogram,': [518], 'aortic': [519], 'pulse': [520, 949], 'wave': [521, 950], 'velocity': [522], '(SphygmoCor,': [523], 'AtCor': [524], 'Medical),': [525], '6-minute': [526, 979], 'walk': [527, 980], 'test,': [528], 'shortness': [531, 1135], 'breath': [533], 'questionnaires.': [534], 'After': [535], 'evaluation,': [538], 'underwent': [541, 658], 'right': [543, 772, 1692], 'catheterization': [545], '(via': [546], 'internal': [548], 'jugular': [549], 'vein)': [550], 'supine': [553, 595], 'position,': [554], 'followed': [555], 'bilateral': [557], 'SNB': [558, 709, 765, 820, 852, 1149], '(15': [559], 'mL': [560], '1%': [562], 'lidocaine': [563], 'each': [565, 651], 'side),': [566], 'level': [569], 'T11–T12,': [571], 'prone': [574], 'position': [575, 2871], 'using': [576], 'fluoroscopic': [577], 'guidance': [578], 'B).': [580], 'Expected': [581], 'duration': [582], 'sympatholytic': [584], 'effects': [585, 846, 1086, 1348], '≤90': [587], 'minutes.': [588, 763, 843], 'All': [589, 679], 'recorded': [592], 'position.Statistical': [596], 'methods': [597], 'included': [598], 'paired': [599], 't': [600], 'tests': [601], 'or': [602, 700, 1250], 'Wilcoxon': [603], 'rank': [604], 'sum': [605], 'tests.': [606], 'Repeated': [607], 'measures': [608], 'analyses': [609], '(0,': [610], '15,': [611], '30,': [612], '45,': [613], '60,': [614], '75,': [615], 'minutes)': [618], 'mixed-effects': [621], 'model': [622], 'used': [624, 643], 'compare': [626], 'arterial': [628, 722, 796, 1051], 'mean,': [629], 'pressure,': [633], 'cardiac': [634, 1037], 'index,': [635], 'systemic': [637, 822, 1046, 2075], 'resistance.': [639], "Tukey's": [640], 'method': [641], 'adjust': [645], 'multiple': [647], 'comparisons': [649], 'postprocedure': [652, 909], 'time': [653], 'point': [654], 'baseline.Five': [656], 'SNB.': [660, 873], 'average': [662, 978], 'age': [663], '56': [665], 'years,': [666], '4/5': [667], 'male,': [670], 'ischemic': [672], 'cardiomyopathy': [673], 'observed': [675, 704, 917, 1083], '2': [677, 2233], 'cases.': [678], 'advanced': [683], 'systolic': [684], 'left': [688, 2078], 'ventricular': [689, 2079], 'ejection': [690, 1555, 1704, 2276, 2542, 2697], 'fraction': [691], '≤20%': [693], 'assessed': [695, 866], 'echocardiogram.No': [698], 'procedural': [699], 'hemodynamic': [701, 845, 1085, 1128], 'complications': [702], '48': [706], 'Bilateral': [708], 'resulted': [710, 766, 1025], 'temporary': [713, 1084], 'reduction': [714, 1029, 1044], 'such': [718], 'mean': [720, 771], 'C).': [730], 'Cardiac': [731, 2741], 'index': [732, 953], 'increased': [733], '1.92': [735], 'L/min/m2': [736, 746], '(95%': [737, 779, 791, 803, 812, 829, 837], 'interval': [739], '[CI],': [740], '1.55–2.29)': [741], '2.54': [745], '(95%C,': [747], 'I': [748], '2.17–2.91;': [749], 'P<0.008)': [750], '30': [752, 817, 842, 849], 'minutes': [753, 790, 818, 850], 'before': [754, 987, 1182], 'starting': [755], 'return': [757], 'values': [760], 'Furthermore,': [764], 'decrease': [769, 920], 'atrial': [773], '21': [776], 'CI,': [780, 792, 804, 813, 830, 838], '13–28)': [781], '16': [785], '8–23;': [793], 'P=0.034).': [794], 'Mean': [795], '89': [800], '77–102)': [805], '72': [809], '59–84;': [814], 'P<0.001)': [815, 840], 'resistance': [824, 1048], '1407': [827], 'dynes·sec·cm−5': [828], '1041–1772)': [831], '808': [835], 'dynes·sec·cm-5': [836], '442–1173;': [839], 'peaked': [847], 'mostly': [854], 'recovered': [855], 'toward': [856], 'end': [858], 'monitoring': [862], 'phase': [863], '(90': [864], 'minutes).We': [865], 'changes': [867, 1113, 1129, 1312], 'biomarkers': [869], 'Levels': [874], 'serum': [876], 'norepinephrine': [877], '(median,': [880], 'interquartile': [881], 'range:': [882], '1202': [883], 'pg/dL,': [884, 893, 904], '892': [885], '3045,': [887], 'versus': [888, 908], 'postprocedure:': [889], '90:': [891], '936': [892], '462': [894], '2095': [896], '[P=0.125).': [897], 'Serum': [898], 'epinephrine': [899], 'baseline:': [902], '250': [903], '<25': [905], '616': [907], '56.5,': [910], '27.5': [911], '73': [913], '(P=0.5).': [914], 'Similarly,': [915], 'we': [916, 996], 'nonsignificant': [919, 944], 'median': [922], '362': [929], 'pg/dL': [930], 'within': [931], '6': [932], 'hours': [933], 'procedure': [936, 974, 991, 1253], '(P=0.19)': [937], 'D)': [939], 'well': [941], 'change': [945], 'central': [947], 'velocity,': [951], 'stiffness,': [956], '7.8±2.4': [958], 'meters': [959, 962, 984], '6.8±1.5': [961], '(P=0.153).': [963], 'Finally,': [964], 'reported': [966], 'improvement': [969], 'during': [972, 2377], 'D).': [976], 'distance': [981], '+31.2±34.5': [983], '(P=0.11).In': [992], 'first-in-man': [994], 'study,': [995], 'new': [999], 'therapeutic': [1000, 1146, 2701], 'approach': [1001, 2005], 'treatment': [1004, 1152, 1698, 2265], 'HF.': [1007], 'procedure,': [1009], 'aimed': [1011], 'modulate': [1013], 'tone': [1017], 'minimally': [1020], 'invasive': [1021], 'regional': [1022], 'block,': [1024], 'marked': [1028], 'filling': [1032], 'increase': [1035], 'output,': [1038], 'primarily': [1039], 'driven': [1040], 'significant': [1043], 'improved': [1050, 1133], 'capacitance.': [1053], 'may': [1058], 'key': [1061], 'player': [1062], 'dysregulation': [1066], 'chronic': [1070, 1157, 2927], 'even': [1072], 'absence': [1075], 'total': [1079], 'body': [1080], 'volume.1,2The': [1082], 'possibly': [1088], 'reduced': [1093, 2696], 'autonomic': [1095], 'tone,': [1098], 'leading': [1099], 'chest': [1108], 'abdomen.5': [1111], 'Hemodynamic': [1112, 1347], 'could': [1114], 'also': [1115], 'modulated': [1118], 'sympatholysis/vasodilation': [1120], 'outside': [1121], 'bed.': [1126], 'associated': [1131], 'self-reported': [1134], 'breath.': [1137], 'These': [1138], 'findings': [1139], 'suggest': [1140], 'that': [1141], 'continued': [1142], 'research': [1143], 'into': [1144], 'use': [1147, 2861], 'potentially': [1156], 'interest.': [1161], 'Lack': [1162], 'control': [1165], 'group': [1166], 'limitation': [1170], 'study.': [1173], 'Further': [1174], 'testing': [1175], 'safety': [1177, 1767], 'efficacy': [1179], 'needed': [1181], 'clinical': [1184, 1707, 1764], 'application.Sources': [1185], 'FundingThis': [1187], 'study': [1188, 1235], 'supported': [1190], 'American': [1192, 1202, 1468, 1516, 1603, 1861, 2186, 2816, 2987, 3009], 'grant': [1195, 1205, 1213], '17MCPRP33460225': [1196, 1206], 'M.F.': [1198], 'Dr': [1199], 'received': [1201], 'National': [1208], 'Institutes': [1209], 'Health': [1211], 'T32': [1212], '5T32HL007101.DisclosuresDr': [1214], 'consults': [1216], 'AxonTherapies': [1218], 'Coridea.': [1220], 'other': [1222, 1242], 'authors': [1223], 'report': [1224], 'no': [1225], 'conflicts': [1226], 'interest.Footnoteshttps://www.ahajournals.org/journal/circData': [1228], 'sharing:': [1229], 'data,': [1231], 'analytic': [1232], 'methods,': [1233], 'materials': [1236], 'will': [1237], 'made': [1239], 'available': [1240], 'researchers': [1243], 'purposes': [1245], 'reproducing': [1247], 'results': [1249], 'replicating': [1251], 'e-mailing': [1255], 'corresponding': [1257], 'author.Manesh': [1258], 'manesh.[email': [1278], 'protected]eduReferences1.': [1279], 'M,': [1281, 1333, 1435, 1447, 1449, 1533, 1570, 1583, 1617, 1665, 1667, 1675, 1722, 1728, 1734, 1782, 1784, 1836, 1896, 1993, 2115, 2135, 2206, 2209, 2216, 2253, 2363, 2396, 2526, 2647, 2849, 2897, 2905, 2942, 2964], 'AF,': [1283], 'Felker': [1284, 1735, 1803, 2161, 2427, 2532, 2908], 'GM.': [1285], 'Role': [1286], 'congestion': [1292, 2868], 'failure.J': [1295], 'Am': [1296], 'Assoc.': [1298], '2017;': [1299, 1356], '6:e006817.': [1300], 'doi:': [1301, 1329, 1358], '10.1161/JAHA.117.006817.LinkGoogle': [1302], 'Scholar2.': [1303], 'Fallick': [1304], 'Sobotka': [1306, 1413, 1729, 1897, 2116], 'PA,': [1307], 'Dunlap': [1308, 1727, 2119], 'ME.': [1309], 'Sympathetically': [1310], 'mediated': [1311], 'capacitance:': [1314], 'venous': [1318, 1366, 1545, 1548, 2069], 'reservoir': [1319], 'cause': [1322], 'decompensation.Circ': [1324], 'Fail.': [1326], '2011;': [1327], '4:669–675.': [1328], '10.1161/CIRCHEARTFAILURE.111.961789.LinkGoogle': [1330], 'Scholar3.': [1331], 'Yalamuri': [1334], 'S,': [1335, 1441, 1443, 1484, 1740, 2141, 2211, 2325, 2416, 2679, 2720, 2754, 2758, 2791], 'Herbert': [1336], 'JT,': [1337], 'Liu': [1338, 1930], 'PR,': [1339], 'MR,': [1341], 'Sandler': [1342], 'A.': [1343], 'Raising': [1344], 'pressure:': [1346], 'stimulation.J': [1352], 'Appl': [1353], 'Physiol': [1354, 1380], '(1985).': [1355], '123:126–127.': [1357], '10.1152/japplphysiol.00069.2017.CrossrefMedlineGoogle': [1359], 'Scholar4.': [1360], 'Greenway': [1361], 'CV.': [1362], 'Blockade': [1363], 'reflex': [1365], 'responses': [1368], 'liver': [1370], 'spleen': [1372], 'hexamethonium,': [1374], 'atropine,': [1375], 'surgical': [1377], 'section.Can': [1378], 'J': [1379, 1592, 1631, 1900, 2331, 2466, 2728, 2766, 2801], 'Pharmacol.': [1381], '1991;': [1382], '69:1284–1287.CrossrefMedlineGoogle': [1383], 'Scholar5.': [1384], 'Fujita': [1385], 'Y.': [1386], 'circulation': [1388], 'following': [1389], 'coeliac': [1390], 'plexus': [1391], 'block.Acta': [1392], 'Anaesthesiol': [1393], 'Scand.': [1394], '1988;': [1395], '32:323–327.CrossrefMedlineGoogle': [1396], 'Scholar': [1397], 'Back': [1399], 'top': [1401], 'Next': [1402], 'FiguresReferencesRelatedDetailsCited': [1403], 'By': [1404], 'Kamat': [1405], 'I,': [1406, 1679, 2410], 'Hajduczok': [1407], 'A,': [1408, 1615, 1677, 1681, 1738, 1744, 1790, 1792, 1806, 2036, 2139, 2150, 2160, 2195, 2201, 2400, 2402, 2408, 2412, 2557, 2764, 2789, 2793, 2834, 2899, 2907, 2946, 2948, 2962], 'Salah': [1409, 1580], 'H,': [1410, 1525, 1581, 1585, 1627, 1746, 2026, 2032, 2154, 2199, 2596, 2639, 2837], 'Lurz': [1411], 'P,': [1412, 1579, 1621, 1629, 1659, 1671, 1724, 1730, 1838, 1898, 1923, 1966, 2030, 2145, 2799, 2839, 2847, 2853, 2952, 2954], 'P': [1414, 1686, 1971, 2117], 'M': [1417, 1903, 2120, 2433, 2500, 2564, 2920], '(2022)': [1418, 1455], 'Catheter-Based': [1419, 2771], 'Management': [1420, 2810], 'Failure,': [1423, 1464, 1561, 1599, 1648, 1713, 1773, 1824, 1827, 1884, 1911, 1914, 1980, 2015, 2057, 2129, 2280, 2441, 2444, 2489, 2510, 2548, 2665, 2668, 2815, 2888], 'Interventional': [1424], 'Clinics,': [1426, 1887], '10.1016/j.iccl.2022.01.005,': [1427], '11:3,': [1428], '(267-277),': [1429], 'Online': [1430, 1475, 1520, 1565, 1610, 1652, 1717, 1777, 1831, 1868, 1891, 1916, 1959, 1986, 2019, 2061, 2131, 2190, 2284, 2309, 2354, 2391, 2448, 2495, 2519, 2552, 2585, 2634, 2670, 2709, 2782, 2823, 2892, 2937, 2994], 'publication': [1431, 1476, 1521, 1566, 1611, 1653, 1718, 1778, 1832, 1869, 1892, 1917, 1960, 1987, 2020, 2062, 2132, 2191, 2285, 2310, 2355, 2392, 2449, 2496, 2520, 2553, 2586, 2635, 2671, 2710, 2783, 2824, 2893, 2938, 2995], 'date:': [1432, 1477, 1522, 1567, 1612, 1654, 1719, 1779, 1833, 1870, 1893, 1918, 1961, 1988, 2021, 2063, 2133, 2192, 2286, 2311, 2356, 2393, 2450, 2497, 2521, 2554, 2587, 2636, 2672, 2711, 2784, 2825, 2894, 2939, 2996], '1-Jul-2022.': [1433], 'Kaye': [1436, 1479, 2250], 'Borlaug': [1438, 1541, 1741, 1787], 'Shah': [1440, 1752], 'Rich': [1442], 'Kapur': [1444, 2640], 'N,': [1445, 1537, 1964, 1997, 2203, 2453, 2461, 2594, 2641, 2649], 'Costanzo': [1446, 2499], 'Brener': [1448], 'Sunagawa': [1450, 1493, 1538, 1807], 'K': [1451, 1494, 1539, 1808, 1999], 'Burkhoff': [1453, 1496, 1526, 1725, 1810, 2259, 2326, 2653], 'D': [1454, 1497, 1811, 1876, 2260, 2369, 2654], 'Venous': [1456, 2473], 'Tone': [1457], 'Stressed': [1459, 1819], 'Blood': [1460, 1820, 1973, 2567], 'Volume': [1461, 1821, 2106, 2975], 'Journal': [1465, 1513, 1558, 1600, 1710, 1770, 1858, 2183, 2545, 2577, 2628, 2817, 2885, 2988], 'College': [1469, 1604, 1862], 'Cardiology,': [1471, 1606, 1864, 2350, 2746, 2883, 2990], '10.1016/j.jacc.2022.02.050,': [1472], '79:18,': [1473], '(1858-1869),': [1474], '1-May-2022.': [1478], 'Wolsk': [1481, 2723], 'E,': [1482, 2314, 2457, 2675, 2677, 2724, 2787], 'Nanayakkara': [1483, 2256], 'Mariani': [1485, 2254], 'J,': [1486, 1492, 1577, 1673, 1732, 1802, 1927, 1995, 2137, 2143, 2148, 2158, 2255, 2317, 2406, 2418, 2600, 2602, 2645, 2726, 2841, 2956, 2960], 'Hassager': [1487], 'Gustafsson': [1489, 2322, 2730], 'F,': [1490, 1529, 1619, 1657, 1840, 2024, 2152, 2323, 2329, 2845], 'Moller': [1491], '(2021)': [1498, 1543, 1593, 1635, 1687, 1754, 1812, 1846, 1877, 1904, 1938, 1972, 2067, 2094, 2121], 'Comprehensive': [1499], 'Physiological': [1500], 'Modeling': [1501], 'Provides': [1502], 'Novel': [1503, 2502], 'Insights': [1504], 'Into': [1505], 'With': [1508, 1854, 1909, 1947, 2236], 'Preserved': [1509, 1855], 'Ejection': [1510, 1856, 2174, 2242], 'Fraction': [1511, 2175], 'Physiology,': [1512], 'Association,': [1518, 2188, 3011], '10:19,': [1519], '5-Oct-2021.': [1523], 'Sorimachi': [1524], 'Verbrugge': [1528, 2151], 'Omote': [1530], 'K,': [1531, 1925, 2319, 2718, 2760, 2830, 2944], 'Obokata': [1532], 'Reddy': [1534, 1747, 1844], 'Y,': [1535, 1991, 2592], 'Takahashi': [1536], 'B': [1542], 'Obesity,': [1544], 'capacitance,': [1546], 'compliance': [1549], 'preserved': [1554, 1703, 2275, 2541], 'fraction,': [1556, 2277, 2543], 'European': [1557, 1709, 1769, 2544, 2880, 2884, 2931], '10.1002/ejhf.2254,': [1562], '23:10,': [1563], '(1648-1658),': [1564], '1-Oct-2021.': [1568], 'Abraham': [1571, 2642], 'W,': [1572, 2034, 2321, 2426, 2455, 2643, 2762, 2828, 2843, 2903, 2958], 'von': [1573], 'Bardeleben': [1574], 'R,': [1575, 1625, 1661, 1786, 1796, 1798, 1929, 2197, 2361, 2398, 2528, 2915, 2950], 'Lindenfeld': [1576], 'Ponikowski': [1578, 1628, 1685, 1723], 'Khan': [1582], 'Sievert': [1584, 1626, 1745], 'Stone': [1586], 'G,': [1587, 1736, 1804, 2428, 2681, 2797, 2851, 2909], 'Anker': [1588, 1633], 'S': [1589, 1634, 1753, 1873, 1968, 2002, 2090, 2093, 2257], 'Butler': [1591, 2157, 2800], 'Device': [1594], 'Therapy': [1595, 1880, 2660], 'Chronic': [1597, 1882, 2439], '10.1016/j.jacc.2021.06.040,': [1607], '78:9,': [1608], '(931-956),': [1609], '1-Aug-2021.': [1613, 1655], 'Jorbenadze': [1614], 'Mahfoud': [1618], 'Adamson': [1620], 'Bekfani': [1622], 'T,': [1623, 1669, 2420, 2590, 2714, 2911], 'Wachter': [1624], 'Cleland': [1630], 'Extra‐cardiac': [1636], 'targets': [1637, 2266], 'management': [1640, 2008], 'cardiometabolic': [1642], 'disease:': [1643], 'Device‐based': [1644], 'therapies,': [1645], 'ESC': [1646, 2013, 2055, 2278], '10.1002/ehf2.13361,': [1649], '8:4,': [1650], '(3327-3338),': [1651], 'Málek': [1656], 'Gajewski': [1658], 'Zymliński': [1660], 'Janczak': [1662], 'Chabowski': [1664], 'Martinca': [1668], 'Neužil': [1670], 'Biegus': [1672], 'Mates': [1674], 'Krüger': [1676], 'Skalský': [1678], 'Bapna': [1680, 1743, 2556], 'Engelman': [1682, 1749, 1841, 2560], 'Z': [1683, 1750, 1842, 2561], 'Surgical': [1688], 'ablation': [1689], 'greater': [1693], 'fraction:': [1705, 2698], 'first‐in‐human': [1706], 'trial,': [1708], '10.1002/ejhf.2209,': [1714], '23:7,': [1715, 1775], '(1134-1143),': [1716], '1-Jul-2021.': [1720, 1780], 'Molinger': [1731], 'Litwin': [1739], 'V,': [1748, 2524, 2795, 2832], 'modulation': [1757], 'failure:': [1760, 2339, 2929], 'mechanistic': [1761], 'overview,': [1762], 'initial': [1763], 'experience,': [1765], 'considerations,': [1768], '10.1002/ejhf.2196,': [1774], '(1076-1084),': [1776], 'DeVore': [1789, 2401, 2906, 2947], 'Lopes': [1795], 'Mentz': [1797, 2164, 2527, 2949], 'Rogers': [1801, 2405], 'Mediated': [1816], 'Changes': [1817], 'JACC:': [1825, 1951, 2442], '10.1016/j.jchf.2020.12.006,': [1828], '9:4,': [1829], '(293-300),': [1830], '1-Apr-2021.': [1834, 1871, 1894], 'Neuzil': [1837], 'Malek': [1839], 'V': [1845], 'Greater': [1847, 2570], 'Stimulation': [1850], 'Fraction,': [1857, 2243], '10.1016/j.jacc.2021.02.048,': [1865], '77:15,': [1866], '(1952-1953),': [1867], 'Doimo': [1872], 'Pavan': [1875], 'Novelties': [1878], '10.1016/j.hfc.2021.01.006,': [1888], '17:2,': [1889], '(255-262),': [1890], 'Piccini': [1899], 'Renal': [1905], 'Denervation': [1906, 2773], 'Circulation:': [1912, 2127, 2666], '14:3,': [1915], '1-Mar-2021.': [1919, 1962], 'Kaiser': [1920, 1936], 'Platzer': [1922], 'Miyashiro': [1924], 'Canfield': [1926], 'St.': [1932], 'Goar': [1933], 'F': [1934, 2731, 2855], 'C': [1937, 2038, 2608, 2615, 2686, 2971], 'First-in-Human': [1939], 'Experience': [1940], 'Mechanical': [1942], 'Preload': [1943, 2125], 'Control': [1944, 2376], 'HFpEF': [1948], 'During': [1949], 'Exercise,': [1950], 'Basic': [1952], 'Translational': [1954, 2580], 'Science,': [1955], '10.1016/j.jacbts.2020.12.007,': [1956], '6:3,': [1957], '(189-198),': [1958], 'Harrison': [1963], 'Pang': [1965, 2798], 'Collins': [1967, 2790], 'Levy': [1970], 'Pressure': [1974, 2568], 'Reduction': [1975], 'Hypertensive': [1977, 2777], 'Current': [1981, 2304, 2511], 'Hypertension': [1982], 'Reports,': [1983, 2306], '10.1007/s11906-021-01127-8,': [1984], '23:2,': [1985], '1-Feb-2021.': [1989, 2022, 2064], 'Shiraishi': [1990], 'Kawana': [1992], 'Nakata': [1994], 'Sato': [1996], 'Fukuda': [1998], 'Kohsaka': [2001], '(2020)': [2003, 2042, 2166, 2222, 2261, 2293, 2335, 2370, 2434, 2467, 2501, 2534, 2609, 2655, 2732], 'Time‐sensitive': [2004], 'failure,': [2012], '10.1002/ehf2.13139,': [2016], '8:1,': [2017, 2059], '(204-221),': [2018], 'Husain‐Syed': [2023], 'Gröne': [2025], 'Assmus': [2027], 'Bauer': [2029], 'Gall': [2031], 'Seeger': [2033], 'Ghofrani': [2035], 'Ronco': [2037], 'Birk': [2040], 'H': [2041, 2769], 'Congestive': [2043], 'nephropathy:': [2044], 'neglected': [2046], 'entity?': [2047], 'Proposal': [2048], 'diagnostic': [2050], 'criteria': [2051], 'future': [2053], 'perspectives,': [2054], '10.1002/ehf2.13118,': [2058], '(183-203),': [2060], 'Bombardini': [2065], 'T': [2066], 'contribution': [2070], 'cardiovascular': [2072], 'performance:': [2073], 'From': [2074, 2181], 'veins': [2076], 'function:': [2080], 'A': [2081, 2218, 2221, 2292, 2334, 2430, 2463, 2651, 2858, 2917, 2968], 'review,': [2082], 'Scripta': [2083], 'Medica,': [2084], '10.5937/scriptamed52-35083,': [2085], '52:4,': [2086], '(299-308),': [2087], '.': [2088, 2750], 'Lim': [2089], 'Kim': [2092], 'Pathophysiology': [2095], 'Cardiorenal': [2097, 2295, 2506], 'Syndrome': [2098, 2296, 2507], 'Use': [2100], 'Diuretics': [2102], 'Ultrafiltration': [2104, 2167], 'Control,': [2107], 'Korean': [2108], 'Circulation': [2109], 'Journal,': [2110, 2933], '10.4070/kcj.2021.0996,': [2111], '51:8,': [2112], '(656)': [2113], 'Extracardiac': [2122], 'Abnormalities': [2123], 'Reserve,': [2126], '14:1,': [2130], '1-Jan-2021.Fudim': [2134], 'Brooksbank': [2136], 'Giczewska': [2138], 'Greene': [2140], 'Grodin': [2142], 'Martens': [2144, 2838], 'Ter': [2146], 'Maaten': [2147, 2316], 'Sharma': [2149], 'Chakraborty': [2153], 'Bart': [2155], 'G': [2162, 2533, 2683], 'R': [2165, 2366], 'Failure:': [2171, 2299, 2738], 'Implications': [2172], 'Early': [2177], 'Response': [2178], 'Treatment': [2180, 2512, 2775], 'CARRESS‐HF,': [2182], '9:24,': [2189], '15-Dec-2020.': [2193], 'Ibrahim': [2194, 2217], 'Ghaleb': [2196], 'Mansour': [2198], 'Hanafy': [2200], 'Mahmoud': [2202], 'Abdelfatah': [2204], 'Elsharef': [2205], 'Kamal': [2207], 'Salama': [2208], 'Elsaughier': [2210], 'Abdel-Wahid': [2212], 'L,': [2213, 2359, 2716], 'Embarek': [2214], 'Mohamed': [2215], 'Abdel-Galeel': [2220], 'Safety': [2223], 'Efficacy': [2225], 'Adding': [2227, 2478], 'Dapagliflozin': [2228], 'Furosemide': [2230], 'Type': [2232], 'Diabetic': [2234], 'Decompensated': [2237, 2663, 2813], 'Reduced': [2241], 'Frontiers': [2244], 'Cardiovascular': [2246, 2515, 2579], '10.3389/fcvm.2020.602251,': [2248], '7': [2249], 'Byrne': [2252], 'Identification': [2262], 'physiologic': [2264], 'favourable': [2268], 'haemodynamic': [2269], 'consequences': [2270], '10.1002/ehf2.12908,': [2281], '7:6,': [2282], '(3685-3693),': [2283], '1-Dec-2020.': [2287], 'Tang': [2288, 2842, 2957], 'W': [2289, 2605], 'Kiang': [2291], 'Dogmas': [2301], 'Advances,': [2303], '10.1007/s11886-020-01384-0,': [2307], '22:11,': [2308], '1-Nov-2020.': [2312], 'Boorsma': [2313], 'ter': [2315], 'Damman': [2318, 2829], 'Dinh': [2320], 'Goldsmith': [2324], 'Zannad': [2328], 'Udelson': [2330, 2644], 'Voors': [2333, 2650, 2961], 'Congestion': [2336], 'contemporary': [2341], 'look': [2342], 'physiology,': [2344], 'diagnosis': [2345], 'treatment,': [2347], 'Nature': [2348], 'Reviews': [2349], '10.1038/s41569-020-0379-7,': [2351], '17:10,': [2352], '(641-655),': [2353], '1-Oct-2020.': [2357], 'Boucher': [2358], 'Benz': [2360], 'Pierotty': [2362], 'de': [2364, 2603], 'Melo': [2365], 'Valenti': [2368], 'Options': [2373, 2513], 'Hepatic': [2378], 'Upper': [2380], 'Abdominal': [2381], 'Minimally': [2382], 'Invasive': [2383], 'Procedures,': [2384], 'Digestive': [2385], 'Disease': [2386], 'Interventions,': [2387], '10.1055/s-0040-1717079,': [2388], '04:03,': [2389], '(237-247),': [2390], '1-Sep-2020.': [2394, 2451, 2498, 2522, 2555], 'Coburn': [2407], 'Johnson': [2409], 'Paul': [2411], 'Coyne': [2413], 'Rao': [2415, 2523], 'Gutierrez': [2417], 'Kiefer': [2419, 2910], 'Kong': [2421, 2912], '10.1016/j.jchf.2020.04.010,': [2445], '8:9,': [2446], '(742-752),': [2447], 'Bouabdallaoui': [2452], 'Beaubien-Souligny': [2454], 'Oussaïd': [2456], 'Henri': [2458], 'Racine': [2460], 'Denault': [2462], 'Rouleau': [2465], 'Assessing': [2468], 'Compartment': [2470], 'Using': [2471], 'Portal': [2472], 'Doppler': [2474], 'Impact': [2476], 'It': [2479], 'EVEREST': [2482], 'Score': [2483], 'Risk': [2485, 2688], 'Assessment': [2486], 'CJC': [2490], 'Open,': [2491], '10.1016/j.cjco.2020.03.012,': [2492], '2:5,': [2493], '(311-320),': [2494], 'Devices': [2503], '10.1007/s11936-020-00823-z,': [2517], '22:9,': [2518, 2550], 'Michos': [2529], 'E': [2530], 'Regional': [2535], 'adiposity': [2536], '10.1002/ejhf.1956,': [2549], '(1540-1550),': [2551], 'Adin': [2558], '(2019)': [2565, 2687, 2770, 2805, 2859], 'Increasing': [2566], 'Stimulation:': [2573], 'Feasibility': [2575], 'Study,': [2576], 'Research,': [2581], '10.1007/s12265-019-09929-7,': [2582], '13:4,': [2583, 2669], '(509-518),': [2584], '1-Aug-2020.': [2588], 'Morgan': [2589], 'Zhang': [2591], 'Pace': [2593], 'Cai': [2595], 'Shen': [2597], 'Wang': [2599], 'Roppolo': [2601], 'Groat': [2604], 'Tai': [2607], 'Thermal': [2610], 'mammalian': [2613], 'unmyelinated': [2614], 'fibers': [2616], 'local': [2618], 'cooling': [2619], '15–25°C': [2621], 'brief': [2624], 'heating': [2625], '45°C,': [2627], 'Neurophysiology,': [2630], '10.1152/jn.00133.2020,': [2631], '123:6,': [2632], '(2173-2179),': [2633], '1-Jun-2020.': [2637], 'Rosenblum': [2638], 'Itkin': [2646], 'Uriel': [2648], 'Conceptual': [2656], 'Considerations': [2657], 'Device-Based': [2659], '1-Apr-2020.': [2673], 'Gronda': [2674], 'Vanoli': [2676], 'Sacchi': [2678], 'Grassi': [2680], 'Ambrosio': [2682], 'Napoli': [2685], 'progression': [2692], 'mechanisms': [2699], 'options,': [2702], 'Reviews,': [2705], '10.1007/s10741-019-09823-z,': [2706], '25:2,': [2707], '(295-303),': [2708], '1-Mar-2020.': [2712], 'Deis': [2713], 'Balling': [2715], 'Rossing': [2717], 'Boesgaard': [2719], 'Kistorp': [2721], 'Gøtze': [2725], 'Rehfeld': [2727], 'Plasma': [2733], 'Somatostatin': [2734], 'Advanced': [2736], 'Filling': [2742], 'Pressures': [2743], 'Outcome,': [2745], '10.1159/000510284,': [2747], '145:12,': [2748], '(769-778),': [2749], 'Zhen': [2751], 'Z,': [2752, 2756], 'Liao': [2753], 'Zhu': [2755], 'Sijia': [2757], 'Au': [2759], 'Lai': [2761], 'Tsang': [2763], 'Hai': [2765], 'Tse': [2768], 'Cardiomyopathy,': [2778], 'Hypertension,': [2779], '74:1,': [2780], '(47-55),': [2781], '1-Jul-2019.': [2785], 'Antohi': [2786], 'Ambrosy': [2788], 'Ahmed': [2792], 'Iliescu': [2794], 'Cotter': [2796], 'Chioncel': [2803], 'O': [2804], 'Therapeutic': [2806], 'Advances': [2807], 'Therapeutics,': [2819], '10.1097/MJT.0000000000000919,': [2820], '26:2,': [2821], '(e222-e233),': [2822], '1-Mar-2019.': [2826], 'Mullens': [2827], 'Harjola': [2831], 'Mebazaa': [2833], 'Brunner-La': [2835], 'Rocca': [2836], 'Testani': [2840], 'Orso': [2844], 'Rossignol': [2846], 'Metra': [2848], 'Filippatos': [2850], 'Seferovic': [2852], 'Ruschitzka': [2854], 'Coats': [2857], 'diuretics': [2863], '-': [2869], 'statement': [2872], 'Society': [2881], '10.1002/ejhf.1369,': [2889], '21:2,': [2890], '(137-155),': [2891], '1-Feb-2019.': [2895], 'Blazing': [2904], '(2018)': [2921, 2972], 'decompensated': [2926], 'splanchnic-HF,': [2930], 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