Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2794353845', 'doi': 'https://doi.org/10.1016/j.phrs.2018.01.021', 'title': 'The role of small molecule platelet-derived growth factor receptor (PDGFR) inhibitors in the treatment of neoplastic disorders', 'display_name': 'The role of small molecule platelet-derived growth factor receptor (PDGFR) inhibitors in the treatment of neoplastic disorders', 'publication_year': 2018, 'publication_date': '2018-02-02', 'ids': {'openalex': 'https://openalex.org/W2794353845', 'doi': 'https://doi.org/10.1016/j.phrs.2018.01.021', 'mag': '2794353845', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29408302'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.phrs.2018.01.021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S54485712', 'display_name': 'Pharmacological Research', 'issn_l': '1043-6618', 'issn': ['1043-6618', '1096-1186'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050801402', 'display_name': 'Robert Roskoski', 'orcid': 'https://orcid.org/0000-0001-9861-4139'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Robert Roskoski', 'raw_affiliation_strings': ['Blue Ridge Institute for Medical Research, 3754 Brevard Road, Suite 116, Box 19, Horse Shoe, NC, 28742-8814, United States'], 'affiliations': [{'raw_affiliation_string': 'Blue Ridge Institute for Medical Research, 3754 Brevard Road, Suite 116, Box 19, Horse Shoe, NC, 28742-8814, United States', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5050801402'], 'corresponding_institution_ids': [], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.197, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 137, 'citation_normalized_percentile': {'value': 0.996503, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '129', 'issue': None, 'first_page': '65', 'last_page': '83'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11485', 'display_name': 'Gastrointestinal Tumor Research and Treatment', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2715', 'display_name': 'Gastroenterology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11485', 'display_name': 'Gastrointestinal Tumor Research and Treatment', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2715', 'display_name': 'Gastroenterology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10253', 'display_name': 'Sarcoma Diagnosis and Treatment', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12278', 'display_name': 'Vascular Tumors and Angiosarcomas', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/platelet-derived-growth-factor', 'display_name': 'Platelet-derived growth factor', 'score': 0.6160635}, {'id': 'https://openalex.org/keywords/pdgfra', 'display_name': 'PDGFRA', 'score': 0.5252851}], 'concepts': [{'id': 'https://openalex.org/C180361614', 'wikidata': 'https://www.wikidata.org/wiki/Q7202242', 'display_name': 'Platelet-derived growth factor receptor', 'level': 4, 'score': 0.872396}, {'id': 'https://openalex.org/C2781294074', 'wikidata': 'https://www.wikidata.org/wiki/Q22327352', 'display_name': 'Platelet-derived growth factor', 'level': 5, 'score': 0.6160635}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.602129}, {'id': 'https://openalex.org/C101544691', 'wikidata': 'https://www.wikidata.org/wiki/Q420511', 'display_name': 'Receptor tyrosine kinase', 'level': 3, 'score': 0.6016043}, {'id': 'https://openalex.org/C26375932', 'wikidata': 'https://www.wikidata.org/wiki/Q118226', 'display_name': 'Growth factor receptor', 'level': 3, 'score': 0.555703}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5554995}, {'id': 'https://openalex.org/C37307934', 'wikidata': 'https://www.wikidata.org/wiki/Q18030422', 'display_name': 'PDGFRA', 'level': 4, 'score': 0.5252851}, {'id': 'https://openalex.org/C42362537', 'wikidata': 'https://www.wikidata.org/wiki/Q87099740', 'display_name': 'Tyrosine kinase', 'level': 3, 'score': 0.4714699}, {'id': 'https://openalex.org/C2775960820', 'wikidata': 'https://www.wikidata.org/wiki/Q408378', 'display_name': 'Growth factor', 'level': 3, 'score': 0.43742168}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4059468}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.37285548}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.27744547}, {'id': 'https://openalex.org/C2775922572', 'wikidata': 'https://www.wikidata.org/wiki/Q83567', 'display_name': 'GiST', 'level': 3, 'score': 0.27467918}, {'id': 'https://openalex.org/C16930146', 'wikidata': 'https://www.wikidata.org/wiki/Q4381253', 'display_name': 'Stromal cell', 'level': 2, 'score': 0.27078727}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.149876}], 'mesh': [{'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D017479', 'descriptor_name': 'Receptors, Platelet-Derived Growth Factor', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008024', 'descriptor_name': 'Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010982', 'descriptor_name': 'Platelet-Derived Growth Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010982', 'descriptor_name': 'Platelet-Derived Growth Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017479', 'descriptor_name': 'Receptors, Platelet-Derived Growth Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017479', 'descriptor_name': 'Receptors, Platelet-Derived Growth Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.phrs.2018.01.021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S54485712', 'display_name': 'Pharmacological Research', 'issn_l': '1043-6618', 'issn': ['1043-6618', '1096-1186'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29408302', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.74}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 121, 'referenced_works': ['https://openalex.org/W1490860457', 'https://openalex.org/W1843891279', 'https://openalex.org/W1875580551', 'https://openalex.org/W1881469793', 'https://openalex.org/W1883414954', 'https://openalex.org/W1891334654', 'https://openalex.org/W1964822816', 'https://openalex.org/W1966285532', 'https://openalex.org/W1968427979', 'https://openalex.org/W1970174659', 'https://openalex.org/W1974133340', 'https://openalex.org/W1975436091', 'https://openalex.org/W1975691556', 'https://openalex.org/W1976096319', 'https://openalex.org/W1978572651', 'https://openalex.org/W1982020713', 'https://openalex.org/W1985588649', 'https://openalex.org/W1986755373', 'https://openalex.org/W1989221709', 'https://openalex.org/W1993675254', 'https://openalex.org/W1996728737', 'https://openalex.org/W2000390423', 'https://openalex.org/W2002711747', 'https://openalex.org/W2003973314', 'https://openalex.org/W2004684799', 'https://openalex.org/W2007750331', 'https://openalex.org/W2011957331', 'https://openalex.org/W2012460154', 'https://openalex.org/W2014446189', 'https://openalex.org/W2014456898', 'https://openalex.org/W2015313106', 'https://openalex.org/W2018950591', 'https://openalex.org/W2019294726', 'https://openalex.org/W2020293198', 'https://openalex.org/W2020455451', 'https://openalex.org/W2025529909', 'https://openalex.org/W2027962993', 'https://openalex.org/W2028160054', 'https://openalex.org/W2028415754', 'https://openalex.org/W2030205108', 'https://openalex.org/W2030379493', 'https://openalex.org/W2033338244', 'https://openalex.org/W2033903396', 'https://openalex.org/W2034975420', 'https://openalex.org/W2038822025', 'https://openalex.org/W2047964609', 'https://openalex.org/W2049885874', 'https://openalex.org/W2050643839', 'https://openalex.org/W2050742442', 'https://openalex.org/W2051515492', 'https://openalex.org/W2052016211', 'https://openalex.org/W2052420692', 'https://openalex.org/W2052550764', 'https://openalex.org/W2054466658', 'https://openalex.org/W2055380229', 'https://openalex.org/W2057898725', 'https://openalex.org/W2063084845', 'https://openalex.org/W2064471338', 'https://openalex.org/W2067405360', 'https://openalex.org/W2070414995', 'https://openalex.org/W2070727232', 'https://openalex.org/W2074644169', 'https://openalex.org/W2074926914', 'https://openalex.org/W2076947916', 'https://openalex.org/W2085895135', 'https://openalex.org/W2087562706', 'https://openalex.org/W2089756110', 'https://openalex.org/W2091455173', 'https://openalex.org/W2093691792', 'https://openalex.org/W2094891357', 'https://openalex.org/W2095675477', 'https://openalex.org/W2106299345', 'https://openalex.org/W2106932520', 'https://openalex.org/W2107532817', 'https://openalex.org/W2110121929', 'https://openalex.org/W2111251689', 'https://openalex.org/W2116922255', 'https://openalex.org/W2118460316', 'https://openalex.org/W2123334268', 'https://openalex.org/W2129093214', 'https://openalex.org/W2136133297', 'https://openalex.org/W2137111502', 'https://openalex.org/W2137428220', 'https://openalex.org/W2139362357', 'https://openalex.org/W2140626630', 'https://openalex.org/W2142859819', 'https://openalex.org/W2144707486', 'https://openalex.org/W2145442626', 'https://openalex.org/W2149442576', 'https://openalex.org/W2150501295', 'https://openalex.org/W2156373035', 'https://openalex.org/W2156905839', 'https://openalex.org/W2171554194', 'https://openalex.org/W2181264912', 'https://openalex.org/W2189707966', 'https://openalex.org/W2225718653', 'https://openalex.org/W2227416752', 'https://openalex.org/W2238792293', 'https://openalex.org/W2297912447', 'https://openalex.org/W2440861704', 'https://openalex.org/W2481496926', 'https://openalex.org/W2560660889', 'https://openalex.org/W2570230847', 'https://openalex.org/W2586891229', 'https://openalex.org/W2590280648', 'https://openalex.org/W2594726310', 'https://openalex.org/W2601673178', 'https://openalex.org/W2607581659', 'https://openalex.org/W2617081687', 'https://openalex.org/W2759314369', 'https://openalex.org/W2760613511', 'https://openalex.org/W2764227426', 'https://openalex.org/W2767051969', 'https://openalex.org/W2767336251', 'https://openalex.org/W2768053702', 'https://openalex.org/W2769616494', 'https://openalex.org/W2777674964', 'https://openalex.org/W2778033843', 'https://openalex.org/W2992837203', 'https://openalex.org/W4241814063', 'https://openalex.org/W4295216797'], 'related_works': ['https://openalex.org/W3031255752', 'https://openalex.org/W2423281006', 'https://openalex.org/W2401482528', 'https://openalex.org/W2380964687', 'https://openalex.org/W2333249666', 'https://openalex.org/W2143555570', 'https://openalex.org/W2061760261', 'https://openalex.org/W2058584439', 'https://openalex.org/W2023447434', 'https://openalex.org/W177390999'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2794353845', 'counts_by_year': [{'year': 2024, 'cited_by_count': 17}, {'year': 2023, 'cited_by_count': 29}, {'year': 2022, 'cited_by_count': 27}, {'year': 2021, 'cited_by_count': 22}, {'year': 2020, 'cited_by_count': 15}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 12}], 'updated_date': '2024-12-16T11:00:35.439962', 'created_date': '2018-03-29'}