Title: Clinical development of tyrosine kinase inhibitors targeted platelet-derived growth factor receptor
Abstract:Platelet-derived growth factor(PDGF)and its receptors(PDGFR)play crucial role in devel- opment and progression of tumor,and are becoming hot targets for research of anti-cancer therapy.Blockade of PDG...Platelet-derived growth factor(PDGF)and its receptors(PDGFR)play crucial role in devel- opment and progression of tumor,and are becoming hot targets for research of anti-cancer therapy.Blockade of PDGF/PDGFR signal transduction pathway can provide a potential and strategic approach to antitumor therapy. In this review,we give an overview about clinical development of pharmaceutical chemical compounds targeted PDGFR.Read More
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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