Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2785455203', 'doi': 'https://doi.org/10.1021/acs.jnatprod.7b00607', 'title': 'Neothioviridamide, a Polythioamide Compound Produced by Heterologous Expression of a <i>Streptomyces</i> sp. Cryptic RiPP Biosynthetic Gene Cluster', 'display_name': 'Neothioviridamide, a Polythioamide Compound Produced by Heterologous Expression of a <i>Streptomyces</i> sp. Cryptic RiPP Biosynthetic Gene Cluster', 'publication_year': 2018, 'publication_date': '2018-01-30', 'ids': {'openalex': 'https://openalex.org/W2785455203', 'doi': 'https://doi.org/10.1021/acs.jnatprod.7b00607', 'mag': '2785455203', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29381067'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/acs.jnatprod.7b00607', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S166799026', 'display_name': 'Journal of Natural Products', 'issn_l': '0163-3864', 'issn': ['0163-3864', '1520-6025'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017872290', 'display_name': 'Teppei Kawahara', 'orcid': 'https://orcid.org/0000-0001-5140-4724'}, 'institutions': [{'id': 'https://openalex.org/I4210104082', 'display_name': 'Japan Biological Informatics Consortium', 'ror': 'https://ror.org/01astg473', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210104082']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Teppei Kawahara', 'raw_affiliation_strings': ['Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan'], 'affiliations': [{'raw_affiliation_string': 'Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan', 'institution_ids': ['https://openalex.org/I4210104082']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091309318', 'display_name': 'Miho Izumikawa', 'orcid': 'https://orcid.org/0000-0001-5277-5260'}, 'institutions': [{'id': 'https://openalex.org/I4210104082', 'display_name': 'Japan Biological Informatics Consortium', 'ror': 'https://ror.org/01astg473', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210104082']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Miho Izumikawa', 'raw_affiliation_strings': ['Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan'], 'affiliations': [{'raw_affiliation_string': 'Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan', 'institution_ids': ['https://openalex.org/I4210104082']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018056429', 'display_name': 'Ikuko Kozone', 'orcid': 'https://orcid.org/0000-0001-6298-1121'}, 'institutions': [{'id': 'https://openalex.org/I4210104082', 'display_name': 'Japan Biological Informatics Consortium', 'ror': 'https://ror.org/01astg473', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210104082']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ikuko Kozone', 'raw_affiliation_strings': ['Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan'], 'affiliations': [{'raw_affiliation_string': 'Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan', 'institution_ids': ['https://openalex.org/I4210104082']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030001281', 'display_name': 'Junko Hashimoto', 'orcid': 'https://orcid.org/0000-0002-3831-1846'}, 'institutions': [{'id': 'https://openalex.org/I4210104082', 'display_name': 'Japan Biological Informatics Consortium', 'ror': 'https://ror.org/01astg473', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210104082']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Junko Hashimoto', 'raw_affiliation_strings': ['Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan'], 'affiliations': [{'raw_affiliation_string': 'Japan Biological Informatics Consortium (JBIC), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan', 'institution_ids': ['https://openalex.org/I4210104082']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026464215', 'display_name': 'Noritaka Kagaya', 'orcid': 'https://orcid.org/0000-0002-0622-983X'}, 'institutions': [{'id': 'https://openalex.org/I73613424', 'display_name': 'National Institute of Advanced Industrial Science and Technology', 'ror': 'https://ror.org/01703db54', 'country_code': 'JP', 'type': 'government', 'lineage': ['https://openalex.org/I73613424']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Noritaka Kagaya', 'raw_affiliation_strings': ['National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan', 'institution_ids': ['https://openalex.org/I73613424']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061238014', 'display_name': 'Hanae Koiwai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hanae Koiwai', 'raw_affiliation_strings': ['Kitasato\rInstitute for Life Sciences, Kitasato University, 1-15-1 Kitasato Sagamihara, Kanagawa 228-8555, Japan'], 'affiliations': [{'raw_affiliation_string': 'Kitasato\rInstitute for Life Sciences, Kitasato University, 1-15-1 Kitasato Sagamihara, Kanagawa 228-8555, Japan', 'institution_ids': ['https://openalex.org/I64189623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061417383', 'display_name': 'Mamoru Komatsu', 'orcid': 'https://orcid.org/0000-0002-1892-1241'}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Mamoru Komatsu', 'raw_affiliation_strings': ['Kitasato\rInstitute for Life Sciences, Kitasato University, 1-15-1 Kitasato Sagamihara, Kanagawa 228-8555, Japan'], 'affiliations': [{'raw_affiliation_string': 'Kitasato\rInstitute for Life Sciences, Kitasato University, 1-15-1 Kitasato Sagamihara, Kanagawa 228-8555, Japan', 'institution_ids': ['https://openalex.org/I64189623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077275866', 'display_name': 'Manabu Fujie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I142637625', 'display_name': 'Okinawa Institute of Science and Technology Graduate University', 'ror': 'https://ror.org/02qg15b79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I142637625']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Manabu Fujie', 'raw_affiliation_strings': ['Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha,\rOnna-son, Kunigami-gun, Okinawa 904-0495, Japan'], 'affiliations': [{'raw_affiliation_string': 'Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha,\rOnna-son, Kunigami-gun, Okinawa 904-0495, Japan', 'institution_ids': ['https://openalex.org/I142637625']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103697607', 'display_name': 'Noriyuki Sato', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I142637625', 'display_name': 'Okinawa Institute of Science and Technology Graduate University', 'ror': 'https://ror.org/02qg15b79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I142637625']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Noriyuki Sato', 'raw_affiliation_strings': ['Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha,\rOnna-son, Kunigami-gun, Okinawa 904-0495, Japan'], 'affiliations': [{'raw_affiliation_string': 'Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha,\rOnna-son, Kunigami-gun, Okinawa 904-0495, Japan', 'institution_ids': ['https://openalex.org/I142637625']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051175802', 'display_name': 'Haruo Ikeda', 'orcid': 'https://orcid.org/0000-0003-3977-7856'}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Haruo Ikeda', 'raw_affiliation_strings': ['Kitasato\rInstitute for Life Sciences, Kitasato University, 1-15-1 Kitasato Sagamihara, Kanagawa 228-8555, Japan'], 'affiliations': [{'raw_affiliation_string': 'Kitasato\rInstitute for Life Sciences, Kitasato University, 1-15-1 Kitasato Sagamihara, Kanagawa 228-8555, Japan', 'institution_ids': ['https://openalex.org/I64189623']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5031272334', 'display_name': 'Kazuo Shin‐ya', 'orcid': 'https://orcid.org/0000-0002-4702-0661'}, 'institutions': [{'id': 'https://openalex.org/I73613424', 'display_name': 'National Institute of Advanced Industrial Science and Technology', 'ror': 'https://ror.org/01703db54', 'country_code': 'JP', 'type': 'government', 'lineage': ['https://openalex.org/I73613424']}, {'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuo Shin-ya', 'raw_affiliation_strings': ['National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan', 'The\rBiotechnology Research Center, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan', 'institution_ids': ['https://openalex.org/I73613424']}, {'raw_affiliation_string': 'The\rBiotechnology Research Center, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan', 'institution_ids': ['https://openalex.org/I74801974']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.978, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 49, 'citation_normalized_percentile': {'value': 0.99991, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '81', 'issue': '2', 'first_page': '264', 'last_page': '269'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10252', 'display_name': 'Natural Products as Sources of New Drugs', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10252', 'display_name': 'Natural Products as Sources of New Drugs', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12827', 'display_name': 'Nucleotide Metabolism and Enzyme Regulation', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10823', 'display_name': 'Global Burden of Leishmaniasis Incidence and Treatment', 'score': 0.9919, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/gene-cluster', 'display_name': 'Gene cluster', 'score': 0.9141768}, {'id': 'https://openalex.org/keywords/heterologous-expression', 'display_name': 'Heterologous expression', 'score': 0.8839744}, {'id': 'https://openalex.org/keywords/heterologous', 'display_name': 'Heterologous', 'score': 0.72989035}, {'id': 'https://openalex.org/keywords/cloning', 'display_name': 'Cloning (programming)', 'score': 0.5735249}, {'id': 'https://openalex.org/keywords/pyrimidine-biosynthesis', 'display_name': 'Pyrimidine Biosynthesis', 'score': 0.508176}], 'concepts': [{'id': 'https://openalex.org/C36857842', 'wikidata': 'https://www.wikidata.org/wiki/Q1501261', 'display_name': 'Gene cluster', 'level': 3, 'score': 0.9141768}, {'id': 'https://openalex.org/C108305142', 'wikidata': 'https://www.wikidata.org/wiki/Q3062286', 'display_name': 'Heterologous expression', 'level': 4, 'score': 0.8839744}, {'id': 'https://openalex.org/C2780115692', 'wikidata': 'https://www.wikidata.org/wiki/Q5747302', 'display_name': 'Heterologous', 'level': 3, 'score': 0.72989035}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.6951071}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6666072}, {'id': 'https://openalex.org/C121050878', 'wikidata': 'https://www.wikidata.org/wiki/Q5135020', 'display_name': 'Cloning (programming)', 'level': 2, 'score': 0.5735249}, {'id': 'https://openalex.org/C2779920670', 'wikidata': 'https://www.wikidata.org/wiki/Q1144013', 'display_name': 'Streptomyces', 'level': 3, 'score': 0.55359554}, {'id': 'https://openalex.org/C553450214', 'wikidata': 'https://www.wikidata.org/wiki/Q851162', 'display_name': 'Biosynthesis', 'level': 3, 'score': 0.5354}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.46970484}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.4572792}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.40949702}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3319307}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.32089987}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.16933194}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.13591036}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C199360897', 'wikidata': 'https://www.wikidata.org/wiki/Q9143', 'display_name': 'Programming language', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005810', 'descriptor_name': 'Multigene Family', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D010456', 'descriptor_name': 'Peptides, Cyclic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013302', 'descriptor_name': 'Streptomyces', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013854', 'descriptor_name': 'Thioamides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019169', 'descriptor_name': 'Jurkat Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015394', 'descriptor_name': 'Molecular Structure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005810', 'descriptor_name': 'Multigene Family', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010456', 'descriptor_name': 'Peptides, Cyclic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013302', 'descriptor_name': 'Streptomyces', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013854', 'descriptor_name': 'Thioamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/acs.jnatprod.7b00607', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S166799026', 'display_name': 'Journal of Natural Products', 'issn_l': '0163-3864', 'issn': ['0163-3864', '1520-6025'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29381067', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320311405', 'funder_display_name': 'Japan Agency for Medical Research and Development', 'award_id': None}, {'funder': 'https://openalex.org/F4320321679', 'funder_display_name': 'Ministry of Economy, Trade and Industry', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 10, 'referenced_works': ['https://openalex.org/W1607443777', 'https://openalex.org/W1996315535', 'https://openalex.org/W2080107925', 'https://openalex.org/W2084447564', 'https://openalex.org/W2090367881', 'https://openalex.org/W2132700081', 'https://openalex.org/W2136991080', 'https://openalex.org/W2142356607', 'https://openalex.org/W2611021352', 'https://openalex.org/W2619592707'], 'related_works': ['https://openalex.org/W4285121642', 'https://openalex.org/W4281482299', 'https://openalex.org/W3127069326', 'https://openalex.org/W2981164982', 'https://openalex.org/W2902337863', 'https://openalex.org/W2785455203', 'https://openalex.org/W2413959608', 'https://openalex.org/W2412524369', 'https://openalex.org/W2363368974', 'https://openalex.org/W2358995494'], 'abstract_inverted_index': {'During': [0, 27], 'genome': [1], 'mining': [2], 'for': [3], 'thioviridamide-like': [4], 'biosynthetic': [5, 24, 32, 39, 61], 'gene': [6, 25, 33, 40, 62], 'clusters': [7], 'that': [8], 'could': [9], 'produce': [10], 'polythioamide': [11], 'RiPP': [12], '(ribosomally': [13], 'synthesized': [14], 'and': [15, 55, 64, 69], 'post-translationally': [16], 'modified': [17], 'peptides),': [18], 'we': [19], 'discovered': [20], 'a': [21, 42], 'novel': [22, 43], 'cryptic': [23], 'cluster.': [26], 'efforts': [28], 'to': [29], 'express': [30], 'this': [31, 38], 'using': [34], 'heterologous': [35, 56], 'expression': [36, 57], 'of': [37, 58, 72], 'cluster,': [41], 'compound': [44], 'designated': [45], 'as': [46], 'neothioviridamide': [47, 60], 'was': [48], 'produced.': [49], 'We': [50], 'report': [51], 'herein': [52], 'the': [53, 59, 65], 'cloning': [54], 'cluster': [63], 'isolation,': [66], 'structure': [67], 'determination,': [68], 'cytotoxic': [70], 'activity': [71], 'neothioviridamide.': [73]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2785455203', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 6}], 'updated_date': '2024-08-08T12:39:19.690158', 'created_date': '2018-02-23'}