Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2765623050', 'doi': 'https://doi.org/10.1111/bjh.14923', 'title': 'Donor‐derived<scp>CD</scp>19‐targeted T cell infusion induces minimal residual disease‐negative remission in relapsed B‐cell acute lymphoblastic leukaemia with no response to donor lymphocyte infusions after haploidentical haematopoietic stem cell transplantation', 'display_name': 'Donor‐derived<scp>CD</scp>19‐targeted T cell infusion induces minimal residual disease‐negative remission in relapsed B‐cell acute lymphoblastic leukaemia with no response to donor lymphocyte infusions after haploidentical haematopoietic stem cell transplantation', 'publication_year': 2017, 'publication_date': '2017-10-26', 'ids': {'openalex': 'https://openalex.org/W2765623050', 'doi': 'https://doi.org/10.1111/bjh.14923', 'mag': '2765623050', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29076142'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/bjh.14923', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjh.14923', 'source': {'id': 'https://openalex.org/S153015021', 'display_name': 'British Journal of Haematology', 'issn_l': '0007-1048', 'issn': ['0007-1048', '1365-2141'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjh.14923', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100457613', 'display_name': 'Yu‐Hong Chen', 'orcid': 'https://orcid.org/0009-0009-8356-0153'}, 'institutions': [{'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}, {'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuhong Chen', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I4210124809', 'https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014867566', 'display_name': 'Yifei Cheng', 'orcid': 'https://orcid.org/0000-0003-2894-9034'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}, {'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yifei Cheng', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I20231570', 'https://openalex.org/I4210124809']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022824092', 'display_name': 'Pan Suo', 'orcid': 'https://orcid.org/0000-0002-5894-3445'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}, {'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Pan Suo', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I20231570', 'https://openalex.org/I4210124809']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100567872', 'display_name': 'Chen‐Hua Yan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}, {'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chenhua Yan', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I20231570', 'https://openalex.org/I4210124809']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100445337', 'display_name': 'Yu Wang', 'orcid': 'https://orcid.org/0000-0003-1253-7465'}, 'institutions': [{'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}, {'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yu Wang', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I4210124809', 'https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100394237', 'display_name': 'Yao Chen', 'orcid': 'https://orcid.org/0000-0001-7231-9860'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}, {'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yao Chen', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I20231570', 'https://openalex.org/I4210124809']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100649717', 'display_name': 'Wei Han', 'orcid': 'https://orcid.org/0000-0002-8578-6780'}, 'institutions': [{'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}, {'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wei Han', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I4210124809', 'https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100424031', 'display_name': 'Lan‐Ping Xu', 'orcid': 'https://orcid.org/0000-0002-0267-1081'}, 'institutions': [{'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}, {'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lanping Xu', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I4210124809', 'https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100724974', 'display_name': 'Xiaohui Zhang', 'orcid': 'https://orcid.org/0000-0003-0245-6792'}, 'institutions': [{'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}, {'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaohui Zhang', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I4210124809', 'https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072208411', 'display_name': 'Kai‐Yan Liu', 'orcid': 'https://orcid.org/0000-0002-6751-7827'}, 'institutions': [{'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}, {'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Kaiyan Liu', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I4210124809', 'https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017056661', 'display_name': 'Lung‐Ji Chang', 'orcid': 'https://orcid.org/0000-0003-2395-5216'}, 'institutions': [{'id': 'https://openalex.org/I4210160476', 'display_name': 'Shenzhen Genoimmune Medical Institute', 'ror': 'https://ror.org/05avj5s69', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210160476']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lungji Chang', 'raw_affiliation_strings': ['Shenzhen Geno-Immune Medical Institute, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Shenzhen Geno-Immune Medical Institute, Beijing, China', 'institution_ids': ['https://openalex.org/I4210160476']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065989466', 'display_name': 'Lei Xiao', 'orcid': 'https://orcid.org/0000-0002-0428-1749'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lei Xiao', 'raw_affiliation_strings': ['Innovative Cellular Therapeutics Co. Ltd, Beijing, China'], 'affiliations': [{'raw_affiliation_string': 'Innovative Cellular Therapeutics Co. Ltd, Beijing, China', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5037029781', 'display_name': 'Xiao‐Jun Huang', 'orcid': 'https://orcid.org/0000-0002-2145-6643'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}, {'id': 'https://openalex.org/I4210124809', 'display_name': "Peking University People's Hospital", 'ror': 'https://ror.org/035adwg89', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124809']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Xiaojun Huang', 'raw_affiliation_strings': ["Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China"], 'affiliations': [{'raw_affiliation_string': "Peking University People's Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation, Collaborative Innovation Centre of Haematology, Peking University, Beijing, China", 'institution_ids': ['https://openalex.org/I20231570', 'https://openalex.org/I4210124809']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5037029781'], 'corresponding_institution_ids': ['https://openalex.org/I20231570', 'https://openalex.org/I4210124809'], 'apc_list': {'value': 4940, 'currency': 'USD', 'value_usd': 4940, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.399, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 96, 'citation_normalized_percentile': {'value': 0.859676, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '179', 'issue': '4', 'first_page': '598', 'last_page': '605'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11491', 'display_name': 'CAR-T cell therapy research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11491', 'display_name': 'CAR-T cell therapy research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10345', 'display_name': 'Hematopoietic Stem Cell Transplantation', 'score': 0.9538, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9449, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/minimal-residual-disease', 'display_name': 'Minimal Residual Disease', 'score': 0.697086}, {'id': 'https://openalex.org/keywords/cytokine-release-syndrome', 'display_name': 'Cytokine Release Syndrome', 'score': 0.6239494}, {'id': 'https://openalex.org/keywords/tocilizumab', 'display_name': 'Tocilizumab', 'score': 0.5290353}, {'id': 'https://openalex.org/keywords/donor-lymphocyte-infusion', 'display_name': 'Donor lymphocyte infusion', 'score': 0.51361156}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8683342}, {'id': 'https://openalex.org/C2779823535', 'wikidata': 'https://www.wikidata.org/wiki/Q6865356', 'display_name': 'Minimal residual disease', 'level': 3, 'score': 0.697086}, {'id': 'https://openalex.org/C2780850621', 'wikidata': 'https://www.wikidata.org/wiki/Q3961647', 'display_name': 'Cytokine release syndrome', 'level': 5, 'score': 0.6239494}, {'id': 'https://openalex.org/C2777408962', 'wikidata': 'https://www.wikidata.org/wiki/Q1128050', 'display_name': 'Hematopoietic stem cell transplantation', 'level': 3, 'score': 0.56001323}, {'id': 'https://openalex.org/C2777178219', 'wikidata': 'https://www.wikidata.org/wiki/Q425154', 'display_name': 'Tocilizumab', 'level': 3, 'score': 0.5290353}, {'id': 'https://openalex.org/C2779695342', 'wikidata': 'https://www.wikidata.org/wiki/Q5296800', 'display_name': 'Donor lymphocyte infusion', 'level': 4, 'score': 0.51361156}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.46660918}, {'id': 'https://openalex.org/C2778384902', 'wikidata': 'https://www.wikidata.org/wiki/Q183134', 'display_name': 'Sepsis', 'level': 2, 'score': 0.44628873}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.44183034}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.43688995}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.4139604}, {'id': 'https://openalex.org/C2911091166', 'wikidata': 'https://www.wikidata.org/wiki/Q106419912', 'display_name': 'Transplantation', 'level': 2, 'score': 0.39693534}, {'id': 'https://openalex.org/C3875195', 'wikidata': 'https://www.wikidata.org/wiki/Q5099363', 'display_name': 'Chimeric antigen receptor', 'level': 4, 'score': 0.3810221}, {'id': 'https://openalex.org/C2778461978', 'wikidata': 'https://www.wikidata.org/wiki/Q29496', 'display_name': 'Leukemia', 'level': 2, 'score': 0.3285269}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.25325936}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.18530625}], 'mesh': [{'descriptor_ui': 'D018941', 'descriptor_name': 'Antigens, CD19', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D016219', 'descriptor_name': 'Immunotherapy, Adoptive', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D015452', 'descriptor_name': 'Precursor B-Cell Lymphoblastic Leukemia-Lymphoma', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D011948', 'descriptor_name': 'Receptors, Antigen, T-Cell', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018941', 'descriptor_name': 'Antigens, CD19', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006086', 'descriptor_name': 'Graft vs Host Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006086', 'descriptor_name': 'Graft vs Host Disease', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D006086', 'descriptor_name': 'Graft vs Host Disease', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006239', 'descriptor_name': 'Haplotypes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018380', 'descriptor_name': 'Hematopoietic Stem Cell Transplantation', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D018380', 'descriptor_name': 'Hematopoietic Stem Cell Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018380', 'descriptor_name': 'Hematopoietic Stem Cell Transplantation', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016219', 'descriptor_name': 'Immunotherapy, Adoptive', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D016219', 'descriptor_name': 'Immunotherapy, Adoptive', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018365', 'descriptor_name': 'Neoplasm, Residual', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015452', 'descriptor_name': 'Precursor B-Cell Lymphoblastic Leukemia-Lymphoma', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D015452', 'descriptor_name': 'Precursor B-Cell Lymphoblastic Leukemia-Lymphoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011948', 'descriptor_name': 'Receptors, Antigen, T-Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011948', 'descriptor_name': 'Receptors, Antigen, T-Cell', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D012074', 'descriptor_name': 'Remission Induction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012074', 'descriptor_name': 'Remission Induction', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D016879', 'descriptor_name': 'Salvage Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016879', 'descriptor_name': 'Salvage Therapy', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000637', 'qualifier_name': 'transplantation', 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/bjh.14923', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjh.14923', 'source': {'id': 'https://openalex.org/S153015021', 'display_name': 'British Journal of Haematology', 'issn_l': '0007-1048', 'issn': ['0007-1048', '1365-2141'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29076142', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/bjh.14923', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjh.14923', 'source': {'id': 'https://openalex.org/S153015021', 'display_name': 'British Journal of Haematology', 'issn_l': '0007-1048', 'issn': ['0007-1048', '1365-2141'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.66, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320327720', 'funder_display_name': 'Foundation for Innovative Research Groups of the National Natural Science Foundation of China', 'award_id': '81621001'}], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W1584309797', 'https://openalex.org/W1773471853', 'https://openalex.org/W1881216623', 'https://openalex.org/W1961611968', 'https://openalex.org/W1967916642', 'https://openalex.org/W1994817793', 'https://openalex.org/W2003623626', 'https://openalex.org/W2009733242', 'https://openalex.org/W2014114903', 'https://openalex.org/W2017772144', 'https://openalex.org/W2019987786', 'https://openalex.org/W2029047332', 'https://openalex.org/W2039334806', 'https://openalex.org/W2045475405', 'https://openalex.org/W2046843493', 'https://openalex.org/W2079110478', 'https://openalex.org/W2082708772', 'https://openalex.org/W2105400883', 'https://openalex.org/W2113704152', 'https://openalex.org/W2265134611', 'https://openalex.org/W2278219357', 'https://openalex.org/W2337837694', 'https://openalex.org/W2396292102', 'https://openalex.org/W2408097265', 'https://openalex.org/W2411916291', 'https://openalex.org/W2463295412', 'https://openalex.org/W2549633191', 'https://openalex.org/W2569050105', 'https://openalex.org/W2594535625', 'https://openalex.org/W3031334171'], 'related_works': ['https://openalex.org/W4393974224', 'https://openalex.org/W4381594543', 'https://openalex.org/W3214604417', 'https://openalex.org/W3142239825', 'https://openalex.org/W2969241243', 'https://openalex.org/W2952260713', 'https://openalex.org/W2917403768', 'https://openalex.org/W2796022095', 'https://openalex.org/W2594853348', 'https://openalex.org/W2525195860'], 'abstract_inverted_index': {'Relapse': [0], 'is': [1], 'a': [2, 31, 123, 134], 'common': [3], 'cause': [4], 'of': [5, 78, 106, 117, 127, 144], 'failure': [6], 'in': [7, 56], 'patients': [8, 71, 109, 139], 'with': [9, 153, 174], 'B-cell': [10], 'acute': [11, 165], 'lymphoblastic': [12, 26], 'leukaemia': [13], '(B-ALL)': [14], 'after': [15, 28, 60, 100, 111, 122, 188], 'haploidentical': [16], 'haematopoietic': [17], 'stem': [18], 'cell': [19], 'transplantation': [20], '(haplo-HSCT),': [21], 'and': [22, 50, 65, 69, 75, 114, 157, 163, 183], 'non-responders': [23], 'to': [24], 'donor': [25], 'infusion': [27, 131, 179], 'HSCT': [29], 'have': [30, 52], 'very': [32], 'poor': [33], 'prognosis.': [34], 'Although': [35], 'donor-derived': [36], 'CD19-directed': [37], 'chimeric': [38], 'antigen': [39], 'receptor-modified': [40], '(CAR)': [41], 'T': [42, 80], 'cells': [43, 81], 'can': [44], 'potentially': [45], 'cure': [46], 'leukaemia,': [47], 'their': [48], 'effectiveness': [49], 'safety': [51], 'not': [53], 'been': [54], 'confirmed': [55], 'relapsed': [57, 110, 186], 'B-ALL': [58, 187], 'cases': [59], 'haplo-HSCT.': [61], 'Between': [62], 'January': [63, 66], '2015': [64], '2017,': [67], 'two': [68, 76, 150], 'four': [70], 'each': [72], 'received': [73], 'one': [74, 93, 115, 158], 'infusions': [77], 'CAR': [79, 177], 'from': [82], 'haplo-HSCT': [83], 'donors.': [84], 'Five': [85, 138], '(83·33%)': [86, 140], 'achieved': [87, 133], 'minimal': [88], 'residual': [89], 'disease': [90, 167], '(MRD)-negative': [91], 'remission;': [92], 'patient': [94, 159], 'was': [95, 172], 'discharged': [96], 'automatically': [97], 'without': [98], 'evaluation': [99], 'developing': [101], 'severe': [102], 'thrombotic': [103], 'microangiopathies.': [104], 'Four': [105], 'five': [107], 'responsive': [108], '2-7': [112], 'months,': [113], 'died': [116], 'sepsis': [118], 'following': [119], 'MRD-negative': [120], 'remission': [121], 'second': [124, 130, 135], 'infusion.': [125], 'None': [126], 'the': [128, 170], 'other': [129], 'recipients': [132], 'complete': [136], 'remission.': [137], 'experienced': [141], 'eight': [142], 'courses': [143], 'grade': [145, 161], '1-3': [146], 'cytokine': [147], 'release': [148], 'syndrome;': [149], 'were': [151], 'treated': [152], 'tocilizumab.': [154], 'Two': [155], '(33·3%)': [156], 'developed': [160], '2': [162], '3': [164], 'graft-versus-host': [166], '(aGVHD),': [168], 'respectively;': [169], 'former': [171], 'controlled': [173], 'glucocorticoids.': [175], 'Donor-derived': [176], 'T-cell': [178], 'seems': [180], 'be': [181], 'effective': [182], 'safe': [184], 'for': [185], 'haplo-HSCT,': [189], 'although': [190], 'larger': [191], 'clinical': [192], 'studies': [193], 'are': [194], 'needed.': [195]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2765623050', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 17}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 14}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 11}], 'updated_date': '2024-12-24T09:26:00.321437', 'created_date': '2017-11-10'}