Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2741876450', 'doi': 'https://doi.org/10.1158/1538-7445.am2017-984', 'title': 'Abstract 984: Identification of potent and highly selective PTEFb inhibitor BAY 1251152 for the treatment of cancer: from p.o. to i.v. application via scaffold hops', 'display_name': 'Abstract 984: Identification of potent and highly selective PTEFb inhibitor BAY 1251152 for the treatment of cancer: from p.o. to i.v. application via scaffold hops', 'publication_year': 2017, 'publication_date': '2017-07-01', 'ids': {'openalex': 'https://openalex.org/W2741876450', 'doi': 'https://doi.org/10.1158/1538-7445.am2017-984', 'mag': '2741876450'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2017-984', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5112471106', 'display_name': 'Ulrich Luecking', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Ulrich T. Luecking', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109212479', 'display_name': 'Arne Scholz', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Arne Scholz', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060874909', 'display_name': 'Dirk Kosemund', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Dirk Kosemund', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056088765', 'display_name': 'Rolf Bohlmann', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Rolf Bohlmann', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039089017', 'display_name': 'Hans Briem', 'orcid': 'https://orcid.org/0000-0002-8498-2448'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Hans Briem', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084853335', 'display_name': 'Philip Lienau', 'orcid': 'https://orcid.org/0000-0002-6048-4559'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Philip Lienau', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040107084', 'display_name': 'Gerhard Siemeister', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Gerhard Siemeister', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073617586', 'display_name': 'Ildiko Terebesi', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Ildiko Terebesi', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085689791', 'display_name': 'Kirstin Meyer', 'orcid': 'https://orcid.org/0000-0002-2228-2550'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Kirstin Meyer', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021470216', 'display_name': 'Katja Prelle', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Katja Prelle', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055992211', 'display_name': 'Ray Valencia', 'orcid': 'https://orcid.org/0009-0004-0712-2980'}, 'institutions': [{'id': 'https://openalex.org/I150569930', 'display_name': 'Bayer (United States)', 'ror': 'https://ror.org/034ffbg36', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I150569930', 'https://openalex.org/I67348948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ray Valencia', 'raw_affiliation_strings': ['2Bayer HealthCare Pharmaceuticals Inc., Whippany, NJ.'], 'affiliations': [{'raw_affiliation_string': '2Bayer HealthCare Pharmaceuticals Inc., Whippany, NJ.', 'institution_ids': ['https://openalex.org/I150569930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103408117', 'display_name': 'Stuart Ince', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I150569930', 'display_name': 'Bayer (United States)', 'ror': 'https://ror.org/034ffbg36', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I150569930', 'https://openalex.org/I67348948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stuart Ince', 'raw_affiliation_strings': ['2Bayer HealthCare Pharmaceuticals Inc., Whippany, NJ.'], 'affiliations': [{'raw_affiliation_string': '2Bayer HealthCare Pharmaceuticals Inc., Whippany, NJ.', 'institution_ids': ['https://openalex.org/I150569930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044740532', 'display_name': 'Franz von Nussbaum', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Franz von Nussbaum', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009359386', 'display_name': 'Dominik Mumberg', 'orcid': 'https://orcid.org/0000-0002-6670-1497'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Dominik Mumberg', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051451842', 'display_name': 'Karl Ziegelbauer', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Karl Ziegelbauer', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103115056', 'display_name': 'Michael Brands', 'orcid': 'https://orcid.org/0000-0002-9106-3327'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Michael Brands', 'raw_affiliation_strings': ['1Bayer Pharma AG, Berlin, Germany;'], 'affiliations': [{'raw_affiliation_string': '1Bayer Pharma AG, Berlin, Germany;', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.58, 'has_fulltext': False, 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.999955, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '77', 'issue': '13_Supplement', 'first_page': '984', 'last_page': '984'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10583', 'display_name': 'Cancer-related Molecular Pathways', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10583', 'display_name': 'Cancer-related Molecular Pathways', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10755', 'display_name': 'HER2/EGFR in Cancer Research', 'score': 0.9895, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10952', 'display_name': 'PI3K/AKT/mTOR signaling in cancer', 'score': 0.9885, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ic50', 'display_name': 'IC50', 'score': 0.65923786}, {'id': 'https://openalex.org/keywords/growth-inhibition', 'display_name': 'Growth inhibition', 'score': 0.4111081}], 'concepts': [{'id': 'https://openalex.org/C2777752497', 'wikidata': 'https://www.wikidata.org/wiki/Q286779', 'display_name': 'IC50', 'level': 3, 'score': 0.65923786}, {'id': 'https://openalex.org/C57992300', 'wikidata': 'https://www.wikidata.org/wiki/Q2066956', 'display_name': 'Potency', 'level': 3, 'score': 0.59181446}, {'id': 'https://openalex.org/C115880899', 'wikidata': 'https://www.wikidata.org/wiki/Q1124247', 'display_name': 'Bay', 'level': 2, 'score': 0.5684804}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.5457333}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.53730977}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.43604058}, {'id': 'https://openalex.org/C96232424', 'wikidata': 'https://www.wikidata.org/wiki/Q4118072', 'display_name': 'Cancer cell', 'level': 3, 'score': 0.4270392}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.4212644}, {'id': 'https://openalex.org/C2779707156', 'wikidata': 'https://www.wikidata.org/wiki/Q5611758', 'display_name': 'Growth inhibition', 'level': 3, 'score': 0.4111081}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.39257607}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.38495257}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.37913907}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.32032403}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19596002}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.18689704}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17444912}, {'id': 'https://openalex.org/C147176958', 'wikidata': 'https://www.wikidata.org/wiki/Q77590', 'display_name': 'Civil engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2017-984', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.79, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W93324281', 'https://openalex.org/W788627627', 'https://openalex.org/W3013225796', 'https://openalex.org/W2755812209', 'https://openalex.org/W2391625088', 'https://openalex.org/W2359394249', 'https://openalex.org/W2240559228', 'https://openalex.org/W2027986338', 'https://openalex.org/W1998854056', 'https://openalex.org/W163493885'], 'abstract_inverted_index': {'Abstract': [0], 'PTEFb/CDK9': [1, 58, 133, 143, 279], 'mediated': [2], 'transcription': [3], 'of': [4, 40, 50, 91, 147, 155, 169, 217, 288, 297, 302, 326, 331, 355, 360, 419, 431, 444], 'short-lived': [5], 'anti-apoptotic': [6], 'survival': [7, 22, 32], 'proteins': [8, 33], 'like': [9], 'Mcl-1': [10], 'and': [11, 21, 84, 118, 189, 206, 214, 240, 260, 284, 421], 'Myc': [12], 'plays': [13], 'a': [14, 89, 137], 'critical': [15], 'role': [16], 'in': [17, 23, 37, 81, 105, 111, 116, 233, 238, 248, 265], 'cancer': [18, 148], 'cell': [19, 93], 'growth': [20], 'various': [24, 112, 162], 'tumor': [25], 'entities': [26], 'including': [27, 161], 'AML.': [28], 'In': [29, 172], 'addition,': [30], 'these': [31], 'play': [34], 'important': [35], 'roles': [36], 'the': [38, 47, 53, 167, 221, 256, 274, 286, 292, 298, 303, 327, 332, 356, 361, 429, 445], 'development': [39, 63], 'resistance': [41], 'to': [42, 140, 166, 174, 254, 435], 'chemotherapy.': [43], 'We': [44], 'previously': [45], 'disclosed': [46], 'preclinical': [48], 'profile': [49], 'BAY': [51, 65, 99, 170, 176, 178, 218, 225, 242, 289, 426], '1143572,': [52, 177], 'first': [54, 293], 'selective,': [55], 'orally': [56], 'available': [57], 'inhibitor': [59, 425], 'that': [60], 'entered': [61], 'clinical': [62], '[1-3].': [64], '1143572': [66, 100], 'had': [67], 'low': [68], 'nanomolar': [69], 'activity': [70, 87], 'against': [71, 78, 88, 199], 'PTEFb/CDK9,': [72], 'an': [73], 'at': [74, 108], 'least': [75], '50-fold': [76], 'selectivity': [77, 198], 'other': [79], 'CDKs': [80], 'enzymatic': [82], 'assays': [83], 'broad': [85], 'anti-proliferative': [86], 'panel': [90], 'tumour': [92, 114], 'lines': [94], 'with': [95, 149, 267], 'sub-micromolar': [96], 'IC50': [97], 'values.': [98], 'also': [101], 'showed': [102], 'single': [103], 'agent': [104], 'vivo': [106], 'efficacy': [107, 229], 'tolerated': [109], 'doses': [110], 'xenograft': [113, 234], 'models': [115, 235], 'mice': [117, 239], 'rats': [119], 'upon': [120, 230], 'once': [121], 'daily': [122], 'oral': [123, 175], 'administration.': [124], 'To': [125], 'fully': [126], 'explore': [127], 'future': [128], 'treatment': [129, 146, 154, 232, 430], 'options': [130], 'using': [131], 'selective': [132, 423], 'inhibitors': [134, 144], 'we': [135], 'initiated': [136], 'follow-up': [138], 'program': [139, 283], 'identify': [141], 'novel': [142], 'for': [145, 291, 306, 335, 364, 428, 448], 'increased': [150, 182, 197], 'potency': [151, 191], 'enabling': [152], 'i.v.': [153, 223, 231, 280, 436], 'patients.': [156], 'Extensive': [157], 'lead': [158, 281], 'optimisation': [159], 'efforts,': [160], 'scaffold': [163, 439], 'hops,': [164], 'led': [165], 'identification': [168], '1251152.': [171], 'comparison': [173], '1251152': [179, 219, 226, 243, 290, 427], 'shows': [180], 'significantly': [181, 210], 'biochemical': [183], '(IC50': [184, 192], 'CDK9': [185], '=': [186, 194], '3': [187], 'nM)': [188], 'cellular': [190], 'MOLM13': [193], '29': [195], 'nM),': [196], 'CDK2': [200], 'as': [201, 203], 'well': [202], 'high': [204, 215], 'permeability': [205], 'no': [207], 'efflux.': [208], 'The': [209], 'reduced': [211], 'therapeutic': [212], 'dose': [213], 'solubility': [216], 'enable': [220], 'desired': [222], 'application.': [224], 'demonstrated': [227], 'excellent': [228], '(e.g.': [236], 'MOLM13)': [237], 'rats.': [241], 'is': [244], 'currently': [245], 'being': [246], 'evaluated': [247], 'Phase': [249], 'I': [250], 'studies': [251], '(NCT02635672;': [252], 'NCT02745743)': [253], 'determine': [255], 'safety,': [257], 'tolerability,': [258], 'pharmacokinetics': [259], 'initial': [261], 'pharmacodynamic': [262], 'biomarker': [263], 'response': [264], 'patients': [266], 'advanced': [268], 'cancer.': [269], 'This': [270], 'presentation': [271], 'will': [272], 'highlight': [273], 'key': [275], 'learnings': [276], 'from': [277, 433], 'our': [278], 'optimization': [282], 'disclose': [285], 'structure': [287], 'time.': [294], '[1]:': [295], 'Proceedings': [296, 325, 354, 443], '107th': [299], 'Annual': [300, 329, 358, 451], 'Meeting': [301, 330, 359, 452], 'American': [304, 333, 362, 446], 'Association': [305, 334, 363, 447], 'Cancer': [307, 318, 336, 346, 365, 375, 449, 462], 'Research;': [308, 337, 366], '2016': [309], 'Apr': [310, 339, 368, 455], '16-20;': [311], 'New': [312], 'Orleans,': [313], 'LA.': [314], 'Philadelphia': [315, 343, 372, 459], '(PA):': [316, 344, 373, 460], 'AACR;': [317, 345, 374, 461], 'Res': [319, 347, 376, 463], '2016;76(14': [320], 'Suppl):Abstract': [321, 349, 378, 465], 'nr': [322, 350, 379, 466], '3022.': [323], '[2]:': [324], '106th': [328, 357], '2015': [338, 367], '18-22;': [340, 369], 'Philadelphia,': [341, 370], 'PA.': [342, 371], '2015;75(15': [348, 377], 'DDT02-02.': [351], 'doi:10.1158/1538-7445.AM2015-DDT02-02.': [352], '[3]:': [353], '2828.': [380], 'doi:10.1158/1538-7445.AM2015-2828': [381], 'Citation': [382], 'Format:': [383], 'Ulrich': [384], 'T.': [385], 'Luecking,': [386], 'Arne': [387], 'Scholz,': [388], 'Dirk': [389], 'Kosemund,': [390], 'Rolf': [391], 'Bohlmann,': [392], 'Hans': [393], 'Briem,': [394], 'Philip': [395], 'Lienau,': [396], 'Gerhard': [397], 'Siemeister,': [398], 'Ildiko': [399], 'Terebesi,': [400], 'Kirstin': [401], 'Meyer,': [402], 'Katja': [403], 'Prelle,': [404], 'Ray': [405], 'Valencia,': [406], 'Stuart': [407], 'Ince,': [408], 'Franz': [409], 'von': [410], 'Nussbaum,': [411], 'Dominik': [412], 'Mumberg,': [413], 'Karl': [414], 'Ziegelbauer,': [415], 'Michael': [416], 'Brands.': [417], 'Identification': [418], 'potent': [420], 'highly': [422], 'PTEFb': [424], 'cancer:': [432], 'p.o.': [434], 'application': [437], 'via': [438], 'hops': [440], '[abstract].': [441], 'In:': [442], 'Research': [450], '2017;': [453], '2017': [454], '1-5;': [456], 'Washington,': [457], 'DC.': [458], '2017;77(13': [464], '984.': [467], 'doi:10.1158/1538-7445.AM2017-984': [468]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2741876450', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2025-01-12T16:50:20.837495', 'created_date': '2017-08-08'}