Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2737436316', 'doi': 'https://doi.org/10.1056/nejmoa1613849', 'title': 'Trial of Tocilizumab in Giant-Cell Arteritis', 'display_name': 'Trial of Tocilizumab in Giant-Cell Arteritis', 'publication_year': 2017, 'publication_date': '2017-07-27', 'ids': {'openalex': 'https://openalex.org/W2737436316', 'doi': 'https://doi.org/10.1056/nejmoa1613849', 'mag': '2737436316', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29020600'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1613849', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1613849?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1613849?articleTools=true', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5042482253', 'display_name': 'John H. Stone', 'orcid': 'https://orcid.org/0000-0001-6588-9435'}, 'institutions': [{'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John H. Stone', 'raw_affiliation_strings': ['Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston'], 'affiliations': [{'raw_affiliation_string': 'Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston', 'institution_ids': ['https://openalex.org/I4210087915', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087072990', 'display_name': 'Katie Tuckwell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210113058', 'display_name': 'Roche (United Kingdom)', 'ror': 'https://ror.org/024tgbv41', 'country_code': 'GB', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I4210113058']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Katie Tuckwell', 'raw_affiliation_strings': ['Roche Products, Welwyn Garden City'], 'affiliations': [{'raw_affiliation_string': 'Roche Products, Welwyn Garden City', 'institution_ids': ['https://openalex.org/I4210113058']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063262030', 'display_name': 'Sophie Dimonaco', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210113058', 'display_name': 'Roche (United Kingdom)', 'ror': 'https://ror.org/024tgbv41', 'country_code': 'GB', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I4210113058']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Sophie Dimonaco', 'raw_affiliation_strings': ['Roche Products, Welwyn Garden City'], 'affiliations': [{'raw_affiliation_string': 'Roche Products, Welwyn Garden City', 'institution_ids': ['https://openalex.org/I4210113058']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016922988', 'display_name': 'Miguel Á. González‐Gay', 'orcid': 'https://orcid.org/0000-0002-7924-7406'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Micki Klearman', 'raw_affiliation_strings': ['Genentech, South San Francisco, CA, Universitätsklinikum Erlangen, Erlangen'], 'affiliations': [{'raw_affiliation_string': 'Genentech, South San Francisco, CA, Universitätsklinikum Erlangen, Erlangen', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091190600', 'display_name': 'Martin Aringer', 'orcid': 'https://orcid.org/0000-0003-4471-8375'}, 'institutions': [{'id': 'https://openalex.org/I4210088053', 'display_name': 'Universitätsklinikum Erlangen', 'ror': 'https://ror.org/0030f2a11', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088053']}, {'id': 'https://openalex.org/I2802849423', 'display_name': 'University Medical Center', 'ror': 'https://ror.org/036pt7h44', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802849423']}, {'id': 'https://openalex.org/I78650965', 'display_name': 'TU Dresden', 'ror': 'https://ror.org/042aqky30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I78650965']}], 'countries': ['DE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Martin Aringer', 'raw_affiliation_strings': ['Department of Rheumatology, Medicine III, University Medical Center and Faculty of Medicine Technische Universität Dresden, Dresden, Universitätsklinikum Erlangen, Erlangen'], 'affiliations': [{'raw_affiliation_string': 'Department of Rheumatology, Medicine III, University Medical Center and Faculty of Medicine Technische Universität Dresden, Dresden, Universitätsklinikum Erlangen, Erlangen', 'institution_ids': ['https://openalex.org/I4210088053', 'https://openalex.org/I2802849423', 'https://openalex.org/I78650965']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083643588', 'display_name': 'Daniël Blockmans', 'orcid': 'https://orcid.org/0000-0001-9783-1780'}, 'institutions': [], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Daniel Blockmans', 'raw_affiliation_strings': ['Department of General Internal Medicine, University Hospitals Gasthuisberg, Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Department of General Internal Medicine, University Hospitals Gasthuisberg, Leuven, Belgium', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005994370', 'display_name': 'Elisabeth Brouwer', 'orcid': 'https://orcid.org/0000-0002-5652-4423'}, 'institutions': [{'id': 'https://openalex.org/I1334415907', 'display_name': 'University Medical Center Groningen', 'ror': 'https://ror.org/03cv38k47', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334415907']}, {'id': 'https://openalex.org/I169381384', 'display_name': 'University of Groningen', 'ror': 'https://ror.org/012p63287', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I169381384']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Elisabeth Brouwer', 'raw_affiliation_strings': ['Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center, Groningen, the Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center, Groningen, the Netherlands', 'institution_ids': ['https://openalex.org/I1334415907', 'https://openalex.org/I169381384']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059764745', 'display_name': 'María C. Cid', 'orcid': 'https://orcid.org/0000-0002-4730-0938'}, 'institutions': [{'id': 'https://openalex.org/I71999127', 'display_name': 'Universitat de Barcelona', 'ror': 'https://ror.org/021018s57', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I71999127']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Maria C. Cid', 'raw_affiliation_strings': ['Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona'], 'affiliations': [{'raw_affiliation_string': 'Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona', 'institution_ids': ['https://openalex.org/I71999127']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062360747', 'display_name': 'Bhaskar Dasgupta', 'orcid': 'https://orcid.org/0000-0002-5523-6534'}, 'institutions': [{'id': 'https://openalex.org/I2800288755', 'display_name': 'Southend University Hospital NHS Foundation Trust', 'ror': 'https://ror.org/05fa42p74', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800288755']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Bhaskar Dasgupta', 'raw_affiliation_strings': ['Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea'], 'affiliations': [{'raw_affiliation_string': 'Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea', 'institution_ids': ['https://openalex.org/I2800288755']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052364538', 'display_name': 'Jürgen Rech', 'orcid': 'https://orcid.org/0000-0002-2569-2029'}, 'institutions': [{'id': 'https://openalex.org/I4210088053', 'display_name': 'Universitätsklinikum Erlangen', 'ror': 'https://ror.org/0030f2a11', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088053']}, {'id': 'https://openalex.org/I181369854', 'display_name': 'Friedrich-Alexander-Universität Erlangen-Nürnberg', 'ror': 'https://ror.org/00f7hpc57', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I181369854']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Juergen Rech', 'raw_affiliation_strings': ['Friedrich–Alexander–University Erlangen–Nürnberg, Department of Internal Medicine 3–Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen'], 'affiliations': [{'raw_affiliation_string': 'Friedrich–Alexander–University Erlangen–Nürnberg, Department of Internal Medicine 3–Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen', 'institution_ids': ['https://openalex.org/I4210088053', 'https://openalex.org/I181369854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028528972', 'display_name': 'Carlo Salvarani', 'orcid': 'https://orcid.org/0000-0001-5426-5133'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Carlo Salvarani', 'raw_affiliation_strings': ['Division of Internal Medicine, Azienda Ospedaliera–Istituto di Ricovero e Cura a Carattere Scientifico di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy'], 'affiliations': [{'raw_affiliation_string': 'Division of Internal Medicine, Azienda Ospedaliera–Istituto di Ricovero e Cura a Carattere Scientifico di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075261558', 'display_name': 'Georg Schett', 'orcid': 'https://orcid.org/0000-0001-8740-9615'}, 'institutions': [{'id': 'https://openalex.org/I4210088053', 'display_name': 'Universitätsklinikum Erlangen', 'ror': 'https://ror.org/0030f2a11', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088053']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Georg Schett', 'raw_affiliation_strings': ['Institute of Clinical Immunology, Universitätsklinikum Erlangen, Erlangen'], 'affiliations': [{'raw_affiliation_string': 'Institute of Clinical Immunology, Universitätsklinikum Erlangen, Erlangen', 'institution_ids': ['https://openalex.org/I4210088053']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079051965', 'display_name': 'Hendrik Schulze‐Koops', 'orcid': 'https://orcid.org/0000-0002-1681-491X'}, 'institutions': [{'id': 'https://openalex.org/I8204097', 'display_name': 'Ludwig-Maximilians-Universität München', 'ror': 'https://ror.org/05591te55', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8204097']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Hendrik Schulze-Koops', 'raw_affiliation_strings': ['Division of Rheumatology and Clinical Immunology, Department of Medicine IV, University of Munich, Munich'], 'affiliations': [{'raw_affiliation_string': 'Division of Rheumatology and Clinical Immunology, Department of Medicine IV, University of Munich, Munich', 'institution_ids': ['https://openalex.org/I8204097']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004355994', 'display_name': 'Robert Spiera', 'orcid': 'https://orcid.org/0000-0003-2911-6800'}, 'institutions': [{'id': 'https://openalex.org/I1281539108', 'display_name': 'Hospital for Special Surgery', 'ror': 'https://ror.org/03zjqec80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281539108']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert Spiera', 'raw_affiliation_strings': ['Hospital for Special Surgery, New York'], 'affiliations': [{'raw_affiliation_string': 'Hospital for Special Surgery, New York', 'institution_ids': ['https://openalex.org/I1281539108']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054201991', 'display_name': 'Sebastian Unizony', 'orcid': 'https://orcid.org/0000-0002-8935-7473'}, 'institutions': [{'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sebastian H. Unizony', 'raw_affiliation_strings': ['Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston'], 'affiliations': [{'raw_affiliation_string': 'Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston', 'institution_ids': ['https://openalex.org/I4210087915', 'https://openalex.org/I136199984']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5012591907', 'display_name': 'Neil Collinson', 'orcid': 'https://orcid.org/0000-0001-6602-7845'}, 'institutions': [{'id': 'https://openalex.org/I4210113058', 'display_name': 'Roche (United Kingdom)', 'ror': 'https://ror.org/024tgbv41', 'country_code': 'GB', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I4210113058']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Neil Collinson', 'raw_affiliation_strings': ['Roche Products, Welwyn Garden City'], 'affiliations': [{'raw_affiliation_string': 'Roche Products, Welwyn Garden City', 'institution_ids': ['https://openalex.org/I4210113058']}]}], 'countries_distinct_count': 7, 'institutions_distinct_count': 13, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 97.936, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 1086, 'citation_normalized_percentile': {'value': 0.999972, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '377', 'issue': '4', 'first_page': '317', 'last_page': '328'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10697', 'display_name': 'Classification and Management of Vasculitides', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10697', 'display_name': 'Classification and Management of Vasculitides', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14015', 'display_name': 'Relapsing Polychondritis and VEXAS Syndrome Research', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12438', 'display_name': 'Diagnosis and Management of Urticaria', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tocilizumab', 'display_name': 'Tocilizumab', 'score': 0.9804976}, {'id': 'https://openalex.org/keywords/giant-cell-arteritis', 'display_name': 'Giant Cell Arteritis', 'score': 0.599661}, {'id': 'https://openalex.org/keywords/tapering', 'display_name': 'Tapering', 'score': 0.5751856}, {'id': 'https://openalex.org/keywords/prednisolone', 'display_name': 'Prednisolone', 'score': 0.4202057}, {'id': 'https://openalex.org/keywords/arteritis', 'display_name': 'Arteritis', 'score': 0.41609094}], 'concepts': [{'id': 'https://openalex.org/C2777178219', 'wikidata': 'https://www.wikidata.org/wiki/Q425154', 'display_name': 'Tocilizumab', 'level': 3, 'score': 0.9804976}, {'id': 'https://openalex.org/C2776712624', 'wikidata': 'https://www.wikidata.org/wiki/Q707816', 'display_name': 'Giant cell arteritis', 'level': 4, 'score': 0.94567263}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8657161}, {'id': 'https://openalex.org/C114138010', 'wikidata': 'https://www.wikidata.org/wiki/Q7684542', 'display_name': 'Tapering', 'level': 2, 'score': 0.5751856}, {'id': 'https://openalex.org/C2780841215', 'wikidata': 'https://www.wikidata.org/wiki/Q422549', 'display_name': 'Glucocorticoid', 'level': 2, 'score': 0.52209556}, {'id': 'https://openalex.org/C77076574', 'wikidata': 'https://www.wikidata.org/wiki/Q2152526', 'display_name': 'Giant cell', 'level': 2, 'score': 0.49363887}, {'id': 'https://openalex.org/C2776715498', 'wikidata': 'https://www.wikidata.org/wiki/Q11426176', 'display_name': 'Prednisolone', 'level': 2, 'score': 0.4202057}, {'id': 'https://openalex.org/C2781343717', 'wikidata': 'https://www.wikidata.org/wiki/Q1751810', 'display_name': 'Arteritis', 'level': 2, 'score': 0.41609094}, {'id': 'https://openalex.org/C11988809', 'wikidata': 'https://www.wikidata.org/wiki/Q412889', 'display_name': 'Interleukin 6', 'level': 3, 'score': 0.41031364}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.40673473}, {'id': 'https://openalex.org/C2776015282', 'wikidata': 'https://www.wikidata.org/wiki/Q644318', 'display_name': 'Vasculitis', 'level': 3, 'score': 0.3907848}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.20494309}, {'id': 'https://openalex.org/C2777575956', 'wikidata': 'https://www.wikidata.org/wiki/Q187255', 'display_name': 'Rheumatoid arthritis', 'level': 2, 'score': 0.13242757}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.10020414}, {'id': 'https://openalex.org/C121684516', 'wikidata': 'https://www.wikidata.org/wiki/Q7600677', 'display_name': 'Computer graphics (images)', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D013700', 'descriptor_name': 'Giant Cell Arteritis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D011241', 'descriptor_name': 'Prednisone', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D019947', 'descriptor_name': 'Receptors, Interleukin-6', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004334', 'descriptor_name': 'Drug Administration Schedule', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013700', 'descriptor_name': 'Giant Cell Arteritis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007279', 'descriptor_name': 'Injections, Subcutaneous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011241', 'descriptor_name': 'Prednisone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011241', 'descriptor_name': 'Prednisone', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D019947', 'descriptor_name': 'Receptors, Interleukin-6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012074', 'descriptor_name': 'Remission Induction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1613849', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1613849?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://pure.rug.nl/ws/files/48443420/nejmoa1613849.pdf', 'pdf_url': 'https://pure.rug.nl/ws/files/48443420/nejmoa1613849.pdf', 'source': {'id': 'https://openalex.org/S4306400420', 'display_name': 'University of Groningen research database (University of Groningen / Centre for Information Technology)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I169381384', 'host_organization_name': 'University of Groningen', 'host_organization_lineage': ['https://openalex.org/I169381384'], 'host_organization_lineage_names': ['University of Groningen'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://research.rug.nl/en/publications/453881e1-b954-417c-a9db-fd478401fe3a', 'pdf_url': 'https://research.rug.nl/files/48443420/nejmoa1613849.pdf', 'source': {'id': 'https://openalex.org/S4306400420', 'display_name': 'University of Groningen research database (University of Groningen / Centre for Information Technology)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I169381384', 'host_organization_name': 'University of Groningen', 'host_organization_lineage': ['https://openalex.org/I169381384'], 'host_organization_lineage_names': ['University of Groningen'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28745999', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1056/nejmoa1613849', 'pdf_url': 'https://www.nejm.org/doi/pdf/10.1056/NEJMoa1613849?articleTools=true', 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.58}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1488642175', 'https://openalex.org/W1974147692', 'https://openalex.org/W1982721909', 'https://openalex.org/W1987316799', 'https://openalex.org/W1989068788', 'https://openalex.org/W1992126131', 'https://openalex.org/W1995278898', 'https://openalex.org/W2010869087', 'https://openalex.org/W2062077446', 'https://openalex.org/W2069962584', 'https://openalex.org/W2086583795', 'https://openalex.org/W2089432985', 'https://openalex.org/W2093961109', 'https://openalex.org/W2097338038', 'https://openalex.org/W2098959715', 'https://openalex.org/W2111894252', 'https://openalex.org/W2115145575', 'https://openalex.org/W2128612872', 'https://openalex.org/W2281611880', 'https://openalex.org/W2288972139', 'https://openalex.org/W2292169217', 'https://openalex.org/W2321155811', 'https://openalex.org/W2387687330', 'https://openalex.org/W2468787467', 'https://openalex.org/W2475997056', 'https://openalex.org/W2553035171', 'https://openalex.org/W3147024200'], 'related_works': ['https://openalex.org/W3158209551', 'https://openalex.org/W2792261031', 'https://openalex.org/W2784384431', 'https://openalex.org/W2737436316', 'https://openalex.org/W2550140927', 'https://openalex.org/W2307127799', 'https://openalex.org/W2088451200', 'https://openalex.org/W2060750487', 'https://openalex.org/W2042636846', 'https://openalex.org/W1968260519'], 'abstract_inverted_index': {'Giant-cell': [0], 'arteritis': [1], 'commonly': [2], 'relapses': [3], 'when': [4], 'glucocorticoids': [5, 13], 'are': [6], 'tapered,': [7], 'and': [8], 'the': [9, 22, 29], 'prolonged': [10], 'use': [11], 'of': [12, 21, 31], 'is': [14], 'associated': [15], 'with': [16, 40], 'side': [17], 'effects.': [18], 'The': [19], 'effect': [20], 'interleukin-6': [23], 'receptor': [24], 'alpha': [25], 'inhibitor': [26], 'tocilizumab': [27], 'on': [28], 'rates': [30], 'relapse': [32], 'during': [33], 'glucocorticoid': [34], 'tapering': [35], 'was': [36], 'studied': [37], 'in': [38], 'patients': [39], 'giant-cell': [41], 'arteritis.': [42]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2737436316', 'counts_by_year': [{'year': 2024, 'cited_by_count': 87}, {'year': 2023, 'cited_by_count': 162}, {'year': 2022, 'cited_by_count': 170}, {'year': 2021, 'cited_by_count': 201}, {'year': 2020, 'cited_by_count': 182}, {'year': 2019, 'cited_by_count': 140}, {'year': 2018, 'cited_by_count': 108}, {'year': 2017, 'cited_by_count': 24}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-09-13T13:18:09.637070', 'created_date': '2017-07-31'}