Publication Information

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'abstract_inverted_index': {'目的研究胡黄连苷Ⅱ对大鼠脑缺血/再灌注过程中cyto': [0], 'C/caspase-9/caspase-3信号通路的影响及其神经保护作用机制。\n': [1], '方法环孢素': [3], '(CsA)': [4], '和苍术苷': [5], '(Atr)': [6], '分别作为cyto': [7], 'C阳性对照和阴性对照，改良Longa法制备缺血2': [8], 'h再灌注24': [9], 'h大鼠脑缺血/再灌注': [10], '(I/R)': [11], '模型。再灌注24': [12], 'h后，TTC染色观察脑梗死体积；免疫组织化学和Western': [13], 'blot检测cyto': [14], 'C、caspase-9、caspase-3表达水平。\n': [15], '结果模型组大鼠脑缺血/再灌注后TTC显示染色脑梗死体积明显增加；免疫组织化学和Western': [17], 'blot显示cyto': [18, 23, 28], 'C、caspase-9、caspase-3表达水平较假手术组明显增多': [19], '(P': [20, 25, 30], '<': [21, 26, 31], '0.05)。治疗组大鼠TTC显示脑梗死体积缩小；免疫组化和Western': [22], 'C、caspase-9、caspase-3表达水平与模型组相比明显降低': [24], '0.05)。与Atr组相比，Atr+胡黄连苷Ⅱ组大鼠脑梗死体积缩小，免疫组化和Western': [27], 'C、caspase-9、caspase-3表达水平减弱': [29], '0.05)。\n': [32], '结论胡黄连苷Ⅱ抑制缺血/再灌注损伤大脑神经凋亡的机制可能与下调cyto': [34], 'C/caspase-9/caspase-3信号通路蛋白有关。': [35]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2672317006', 'counts_by_year': [], 'updated_date': '2024-12-12T07:21:29.680276', 'created_date': '2017-06-30'}