Title: Evaluation of Tinidazole (Fasigyn) in the treatment of periodontal disease
Abstract: The present study was conducted to determine the efficacy of Tinidazole (Fasigyn) in the treatment of periodontal diseases.
Two groups of adult periodontitis patients (Russell's index score 6)were divided into 2 groups:
GROUP I:20 patients were treated with scaling and root planning plus
mitronidazole (flagyl).
GROUP II:20 patients were treated with scaling and root planning plus Tinidazole
All the patients were given oral hygiene instructions and submitted to clinical study including :
Plaque index, gingival index, probing depth, loss of attachment
*A biopsy was taken from each patient and was prepared for histological examination.
The clinical study and taking a biopsy were performed two times, one before the start of the treatment and other 4 weeks later.
The following results and conclusions were obtained:
1-There was significant improvement (clinical and histological) with treatment of adult periodontitis with Tinidazole(Fasigyn).
2-The improvement obtained with Tinidazole(Fasigyn) was parallel to that obtained with mitronidazole(Flagyl), in combination with scaling and root planning but without the adverse gastrointestinal reactions of Flagyl.
3-Tinidazole(Fasigyn)can be considered as a valuable drug against oral and anaerobic bacteria which gives rapid and good improvement.
4-Further investigations about the efficacy of Tinidazole in the treatment of different categories of periodontitis must be performed.
Publication Year: 1991
Publication Date: 1991-01-01
Language: en
Type: article
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