Publication Information

{'id': 'https://openalex.org/W2573398098', 'doi': 'https://doi.org/10.18632/oncotarget.14733', 'title': 'Metabolism, toxicity and anticancer activities of arsenic compounds', 'display_name': 'Metabolism, toxicity and anticancer activities of arsenic compounds', 'publication_year': 2017, 'publication_date': '2017-01-18', 'ids': {'openalex': 'https://openalex.org/W2573398098', 'doi': 'https://doi.org/10.18632/oncotarget.14733', 'mag': '2573398098', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28108741', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5410354'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.14733', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14733&path%5B%5D=47045', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14733&path%5B%5D=47045', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100988641', 'display_name': 'Islam Khairul', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Islam Khairul', 'raw_affiliation_strings': ['Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083735838', 'display_name': 'Qian Qian Wang', 'orcid': 'https://orcid.org/0000-0001-5084-3450'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qian Qian Wang', 'raw_affiliation_strings': ['College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China', 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023713311', 'display_name': 'Yu Jiang', 'orcid': 'https://orcid.org/0000-0002-0560-5792'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I31847773', 'display_name': 'Zhejiang Ocean University', 'ror': 'https://ror.org/03mys6533', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I31847773']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yu Han Jiang', 'raw_affiliation_strings': ['Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China', 'Ocean College, Zhejiang University, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Ocean College, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692', 'https://openalex.org/I31847773']}, {'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100407017', 'display_name': 'Chao Wang', 'orcid': 'https://orcid.org/0000-0002-6251-7908'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chao Wang', 'raw_affiliation_strings': ['Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5015235822', 'display_name': 'Hua Naranmandura', 'orcid': 'https://orcid.org/0000-0003-0799-2340'}, 'institutions': [{'id': 'https://openalex.org/I76130692', 'display_name': 'Zhejiang University', 'ror': 'https://ror.org/00a2xv884', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76130692']}, {'id': 'https://openalex.org/I31847773', 'display_name': 'Zhejiang Ocean University', 'ror': 'https://ror.org/03mys6533', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I31847773']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hua Naranmandura', 'raw_affiliation_strings': ['College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China', 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China', 'Ocean College, Zhejiang University, Hangzhou, China'], 'affiliations': [{'raw_affiliation_string': 'Ocean College, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692', 'https://openalex.org/I31847773']}, {'raw_affiliation_string': 'Department of Toxicology, School of Medicine and Public Health, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692']}, {'raw_affiliation_string': 'College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China', 'institution_ids': ['https://openalex.org/I76130692']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.18, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 275, 'citation_normalized_percentile': {'value': 0.984375, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '8', 'issue': '14', 'first_page': '23905', 'last_page': '23926'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10710', 'display_name': 'Arsenic contamination and mitigation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2304', 'display_name': 'Environmental Chemistry'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10710', 'display_name': 'Arsenic contamination and mitigation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2304', 'display_name': 'Environmental Chemistry'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11559', 'display_name': 'Retinoids in leukemia and cellular processes', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11107', 'display_name': 'Selenium in Biological Systems', 'score': 0.994, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/arsenic-toxicity', 'display_name': 'Arsenic toxicity', 'score': 0.79434013}, {'id': 'https://openalex.org/keywords/arsenic-trioxide', 'display_name': 'Arsenic Trioxide', 'score': 0.60193086}, {'id': 'https://openalex.org/keywords/detoxification', 'display_name': 'Detoxification', 'score': 0.51474786}, {'id': 'https://openalex.org/keywords/arsenic-poisoning', 'display_name': 'Arsenic poisoning', 'score': 0.4692535}, {'id': 'https://openalex.org/keywords/chronic-bronchitis', 'display_name': 'Chronic bronchitis', 'score': 0.46239483}], 'concepts': [{'id': 'https://openalex.org/C502230775', 'wikidata': 'https://www.wikidata.org/wiki/Q871', 'display_name': 'Arsenic', 'level': 2, 'score': 0.8411873}, {'id': 'https://openalex.org/C172507514', 'wikidata': 'https://www.wikidata.org/wiki/Q730249', 'display_name': 'Arsenic toxicity', 'level': 3, 'score': 0.79434013}, {'id': 'https://openalex.org/C114246631', 'wikidata': 'https://www.wikidata.org/wiki/Q187661', 'display_name': 'Carcinogen', 'level': 2, 'score': 0.6333598}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.6283889}, {'id': 'https://openalex.org/C2780386689', 'wikidata': 'https://www.wikidata.org/wiki/Q7739', 'display_name': 'Arsenic trioxide', 'level': 3, 'score': 0.60193086}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.5565031}, {'id': 'https://openalex.org/C2780497538', 'wikidata': 'https://www.wikidata.org/wiki/Q1192006', 'display_name': 'Detoxification (alternative medicine)', 'level': 3, 'score': 0.51474786}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.47146446}, {'id': 'https://openalex.org/C2778497195', 'wikidata': 'https://www.wikidata.org/wiki/Q730249', 'display_name': 'Arsenic poisoning', 'level': 3, 'score': 0.4692535}, {'id': 'https://openalex.org/C2992694001', 'wikidata': 'https://www.wikidata.org/wiki/Q173022', 'display_name': 'Chronic bronchitis', 'level': 2, 'score': 0.46239483}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41829425}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.23830897}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19370729}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.1431328}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001152', 'descriptor_name': 'Arsenicals', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020261', 'descriptor_name': 'Arsenic Poisoning', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015473', 'descriptor_name': 'Leukemia, Promyelocytic, Acute', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.14733', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14733&path%5B%5D=47045', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5410354', 'pdf_url': 'https://europepmc.org/articles/pmc5410354?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410354', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28108741', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.14733', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=14733&path%5B%5D=47045', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.55, 'id': 'https://metadata.un.org/sdg/14', 'display_name': 'Life below water'}, {'score': 0.43, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 188, 'referenced_works': ['https://openalex.org/W1505133202', 'https://openalex.org/W1516234656', 'https://openalex.org/W1558353082', 'https://openalex.org/W1642823164', 'https://openalex.org/W1856932102', 'https://openalex.org/W1891304457', 'https://openalex.org/W1896003389', 'https://openalex.org/W1960489659', 'https://openalex.org/W1966452132', 'https://openalex.org/W1966494491', 'https://openalex.org/W1966736242', 'https://openalex.org/W1968857972', 'https://openalex.org/W1972483697', 'https://openalex.org/W1973290552', 'https://openalex.org/W1973656650', 'https://openalex.org/W1975218863', 'https://openalex.org/W1975412826', 'https://openalex.org/W1977896790', 'https://openalex.org/W1979861889', 'https://openalex.org/W1981313350', 'https://openalex.org/W1982330330', 'https://openalex.org/W1983375741', 'https://openalex.org/W1984105235', 'https://openalex.org/W1984196841', 'https://openalex.org/W1985158717', 'https://openalex.org/W1985350181', 'https://openalex.org/W1985800606', 'https://openalex.org/W1985869400', 'https://openalex.org/W1986054311', 'https://openalex.org/W1987559481', 'https://openalex.org/W1987873876', 'https://openalex.org/W1990830351', 'https://openalex.org/W1991701837', 'https://openalex.org/W1992444784', 'https://openalex.org/W1992823317', 'https://openalex.org/W1993927366', 'https://openalex.org/W1994443290', 'https://openalex.org/W1995291627', 'https://openalex.org/W1995338674', 'https://openalex.org/W1996319492', 'https://openalex.org/W1997316542', 'https://openalex.org/W1997616971', 'https://openalex.org/W1998312178', 'https://openalex.org/W1999210054', 'https://openalex.org/W1999419484', 'https://openalex.org/W2000916962', 'https://openalex.org/W2001236388', 'https://openalex.org/W2001884181', 'https://openalex.org/W2002721333', 'https://openalex.org/W2003760570', 'https://openalex.org/W2004284483', 'https://openalex.org/W2004891851', 'https://openalex.org/W2005449426', 'https://openalex.org/W2006455961', 'https://openalex.org/W2006777365', 'https://openalex.org/W2007084427', 'https://openalex.org/W2007734159', 'https://openalex.org/W2007782053', 'https://openalex.org/W2008084371', 'https://openalex.org/W2009103131', 'https://openalex.org/W2013131528', 'https://openalex.org/W2016842735', 'https://openalex.org/W2017289228', 'https://openalex.org/W2018837893', 'https://openalex.org/W2020519436', 'https://openalex.org/W2021081512', 'https://openalex.org/W2021280825', 'https://openalex.org/W2022052232', 'https://openalex.org/W2024067785', 'https://openalex.org/W2024244294', 'https://openalex.org/W2024475665', 'https://openalex.org/W2029583268', 'https://openalex.org/W2031153505', 'https://openalex.org/W2032890395', 'https://openalex.org/W2033424457', 'https://openalex.org/W2033638867', 'https://openalex.org/W2033690461', 'https://openalex.org/W2035029439', 'https://openalex.org/W2035072156', 'https://openalex.org/W2035866481', 'https://openalex.org/W2037632266', 'https://openalex.org/W2038296089', 'https://openalex.org/W2038356928', 'https://openalex.org/W2039369633', 'https://openalex.org/W2043534420', 'https://openalex.org/W2043733236', 'https://openalex.org/W2045823138', 'https://openalex.org/W2045978319', 'https://openalex.org/W2047163415', 'https://openalex.org/W2047925472', 'https://openalex.org/W2047975812', 'https://openalex.org/W2048553024', 'https://openalex.org/W2049752837', 'https://openalex.org/W2050517626', 'https://openalex.org/W2050776078', 'https://openalex.org/W2051329265', 'https://openalex.org/W2052583992', 'https://openalex.org/W2053299183', 'https://openalex.org/W2053658205', 'https://openalex.org/W2055239621', 'https://openalex.org/W2055367666', 'https://openalex.org/W2057596050', 'https://openalex.org/W2059890696', 'https://openalex.org/W2064912565', 'https://openalex.org/W206710202', 'https://openalex.org/W2068753862', 'https://openalex.org/W2072826534', 'https://openalex.org/W2074743285', 'https://openalex.org/W2075596346', 'https://openalex.org/W2077436981', 'https://openalex.org/W2078572304', 'https://openalex.org/W2079017256', 'https://openalex.org/W2079352037', 'https://openalex.org/W2081213990', 'https://openalex.org/W2083983543', 'https://openalex.org/W2086110860', 'https://openalex.org/W2086201153', 'https://openalex.org/W2086371406', 'https://openalex.org/W2087366668', 'https://openalex.org/W2087529306', 'https://openalex.org/W2090400273', 'https://openalex.org/W2091307455', 'https://openalex.org/W2093964285', 'https://openalex.org/W2094553808', 'https://openalex.org/W2094911226', 'https://openalex.org/W2099013774', 'https://openalex.org/W2099303078', 'https://openalex.org/W2104105086', 'https://openalex.org/W2105300242', 'https://openalex.org/W2109585734', 'https://openalex.org/W2110244716', 'https://openalex.org/W2113134560', 'https://openalex.org/W2115344558', 'https://openalex.org/W2117208569', 'https://openalex.org/W2117870498', 'https://openalex.org/W2118521643', 'https://openalex.org/W2118956613', 'https://openalex.org/W2123111610', 'https://openalex.org/W2125136235', 'https://openalex.org/W2127185984', 'https://openalex.org/W2128293827', 'https://openalex.org/W2129976732', 'https://openalex.org/W2132103430', 'https://openalex.org/W2133644385', 'https://openalex.org/W2134063675', 'https://openalex.org/W2138611793', 'https://openalex.org/W2140418591', 'https://openalex.org/W2141102313', 'https://openalex.org/W2142297042', 'https://openalex.org/W2142465931', 'https://openalex.org/W2143070196', 'https://openalex.org/W2148202668', 'https://openalex.org/W2148733641', 'https://openalex.org/W2151625463', 'https://openalex.org/W2151681632', 'https://openalex.org/W2153074213', 'https://openalex.org/W2153224441', 'https://openalex.org/W2158087004', 'https://openalex.org/W2163666912', 'https://openalex.org/W2164569497', 'https://openalex.org/W2167586301', 'https://openalex.org/W2168613545', 'https://openalex.org/W2170325085', 'https://openalex.org/W2170376409', 'https://openalex.org/W2171421571', 'https://openalex.org/W2183232481', 'https://openalex.org/W2199816912', 'https://openalex.org/W2266492282', 'https://openalex.org/W2278454012', 'https://openalex.org/W2320429677', 'https://openalex.org/W2320889530', 'https://openalex.org/W2330155193', 'https://openalex.org/W2334110263', 'https://openalex.org/W2334927193', 'https://openalex.org/W2395188221', 'https://openalex.org/W2414324194', 'https://openalex.org/W2417286298', 'https://openalex.org/W2494607588', 'https://openalex.org/W2532179689', 'https://openalex.org/W2980162142', 'https://openalex.org/W4239928604', 'https://openalex.org/W4242891770', 'https://openalex.org/W4290437308', 'https://openalex.org/W4291980969', 'https://openalex.org/W43589343', 'https://openalex.org/W576666103', 'https://openalex.org/W622196777', 'https://openalex.org/W7064723'], 'related_works': ['https://openalex.org/W3113264836', 'https://openalex.org/W3049131487', 'https://openalex.org/W2771539022', 'https://openalex.org/W2370482557', 'https://openalex.org/W2354496245', 'https://openalex.org/W2270553459', 'https://openalex.org/W2115063820', 'https://openalex.org/W2111967064', 'https://openalex.org/W2067230218', 'https://openalex.org/W1582228066'], 'abstract_inverted_index': {'//': [0, 57], 'Islam': [1], 'Khairul': [2], '1': [3, 17, 22], ',': [4, 9, 14], 'Qian': [5, 6], 'Wang': [7, 16], '1,2': [8], 'Yu': [10], 'Han': [11], 'Jiang': [12], '1,3': [13], 'Chao': [15], 'and': [18, 29, 88, 97, 148, 189, 227, 245, 289], 'Hua': [19, 54], 'Naranmandura': [20], '1,2,3': [21], 'Department': [23], 'of': [24, 27, 38, 82, 114, 116, 136, 170, 176, 209, 217, 221, 225, 242, 251, 262, 266, 282, 297], 'Toxicology,': [25], 'School': [26], 'Medicine': [28], 'Public': [30], 'Health,': [31], 'Zhejiang': [32, 41, 48], 'University,': [33, 42, 49], 'Hangzhou,': [34, 43, 50], 'China': [35, 44, 51], '2': [36, 199], 'College': [37], 'Pharmaceutical': [39], 'Sciences,': [40], '3': [45, 201], 'Ocean': [46], 'College,': [47], 'Correspondence': [52], 'to:': [53], 'Naranmandura,': [55], 'email:': [56], 'Keywords': [58], ':': [59, 65, 70, 75], 'arsenite,': [60], 'acute': [61], 'promyelocytic': [62], 'leukemia': [63], 'Received': [64], 'November': [66], '23,': [67], '2016': [68], 'Accepted': [69], 'January': [71, 76], '11,': [72], '2017': [73, 78], 'Published': [74], '18,': [77], 'Abstract': [79], 'A': [80], 'variety': [81], 'studies': [83, 101, 164], 'indicated': [84, 167], 'that': [85, 104, 168, 183], 'inorganic': [86, 137, 171], 'arsenic': [87, 109, 129, 138, 150, 185, 196, 226, 252, 277, 285], 'its': [89, 228, 263], 'methylated': [90, 178, 229, 284], 'metabolites': [91, 230, 286], 'have': [92, 102, 165, 274], 'paradoxical': [93], 'effects,': [94], 'namely,': [95], 'carcinogenic': [96], 'anticancer': [98], 'effects.': [99], 'Epidemiological': [100], 'shown': [103], 'long': [105, 153], 'term': [106], 'exposure': [107], 'to': [108, 146], 'can': [110], 'increase': [111], 'the': [112, 128, 133, 174, 193, 210, 215, 222, 243, 259, 280, 283, 291, 295], 'risk': [113], 'cancers': [115], 'lung,': [117], 'skin': [118], 'or': [119], 'bladder': [120], 'in': [121, 231, 253, 270, 287, 290], 'man,': [122], 'which': [123], 'is': [124, 180, 234, 256], 'probably': [125], 'associated': [126], 'with': [127, 248], 'metabolism.': [130], 'In': [131], 'fact,': [132], 'enzymatic': [134], 'conversion': [135], 'by': [139], 'Arsenic': [140], '(+3': [141], 'oxidation': [142], 'state)': [143], 'methyltransferase': [144], '(AS3MT)': [145], 'mono-': [147], 'dimethylated': [149], 'species': [151], 'has': [152, 203], 'been': [154, 205], 'considered': [155], 'as': [156, 186, 207], 'a': [157, 181, 187, 190, 239], 'major': [158], 'route': [159], 'for': [160, 214, 294], 'detoxification.': [161], 'However,': [162, 219], 'several': [163], 'also': [166], 'biomethylation': [169], 'arsenic,': [172], 'particularly': [173], 'production': [175], 'trivalent': [177], 'metabolites,': [179], 'process': [182], 'activates': [184], 'toxin': [188], 'carcinogen.': [191], 'On': [192], 'other': [194], 'hand,': [195], 'trioxide': [197], '(As': [198], 'O': [200], ')': [202], 'recently': [204], 'recognized': [206], 'one': [208], 'most': [211], 'effective': [212], 'drugs': [213], 'treatment': [216], 'APL.': [218], 'elaboration': [220], 'cytotoxic': [223], 'mechanisms': [224, 265], 'eradicating': [232], 'cancer': [233], 'sorely': [235], 'lacking.': [236], 'To': [237], 'provide': [238], 'deeper': [240], 'understanding': [241, 261], 'toxicity': [244, 288], 'carcinogenicity': [246], 'along': [247], 'them': [249], 'use': [250], 'chemotherapy,': [254], 'caution': [255], 'required': [257], 'considering': [258], 'poor': [260], 'various': [264], 'exerting': [267], 'toxicity.': [268], 'Thereby,': [269], 'this': [271], 'review,': [272], 'we': [273], 'focused': [275], 'on': [276], 'metabolic': [278], 'pathway,': [279], 'roles': [281], 'therapeutic': [292], 'efficacy': [293], 'treatments': [296], 'solid': [298], 'tumors,': [299], 'APL': [300], 'and/or': [301], 'non-APL': [302], 'malignancies.': [303]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2573398098', 'counts_by_year': [{'year': 2024, 'cited_by_count': 38}, {'year': 2023, 'cited_by_count': 45}, {'year': 2022, 'cited_by_count': 41}, {'year': 2021, 'cited_by_count': 51}, {'year': 2020, 'cited_by_count': 30}, {'year': 2019, 'cited_by_count': 31}, {'year': 2018, 'cited_by_count': 26}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-12-07T23:05:53.822720', 'created_date': '2017-01-26'}