Title: The Biophysical Mutation in Genetic Diseases
Abstract:Sickle-cell anemia is caused mutation at molecular point-6 of hemoglobin beta polypeptide chain that would be bisectional significant site shows a deleterious mutation. P53 is a tumor suppresor protei...Sickle-cell anemia is caused mutation at molecular point-6 of hemoglobin beta polypeptide chain that would be bisectional significant site shows a deleterious mutation. P53 is a tumor suppresor protein having a curious interaction between molecular point and amino acid composition and is inactivated by several biophysical mutations at its core domain with fall of thermodynamic stability tends to disorder.Read More
Publication Year: 2016
Publication Date: 2016-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot