Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2418446309', 'doi': None, 'title': 'Serotonergic modulation of cortical rat noradrenergic system in the mechanism of action of antidepressant drugs.', 'display_name': 'Serotonergic modulation of cortical rat noradrenergic system in the mechanism of action of antidepressant drugs.', 'publication_year': 1985, 'publication_date': '1985-01-01', 'ids': {'openalex': 'https://openalex.org/W2418446309', 'mag': '2418446309', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/4034853'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4034853', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5026906709', 'display_name': 'N. Brunello', 'orcid': 'https://orcid.org/0000-0002-0848-4754'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Brunello N', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086700125', 'display_name': 'Italo Mocchetti', 'orcid': 'https://orcid.org/0000-0002-5010-636X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Mocchetti I', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032512290', 'display_name': 'Andrea Volterra', 'orcid': 'https://orcid.org/0000-0003-1069-1602'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Volterra A', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031333305', 'display_name': 'Virginia Cuomo', 'orcid': 'https://orcid.org/0000-0001-9922-583X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Cuomo', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5040561724', 'display_name': 'Giorgio Racagni', 'orcid': 'https://orcid.org/0000-0002-9396-4647'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Racagni G', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.504545, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 78, 'max': 79}, 'biblio': {'volume': '21', 'issue': '3', 'first_page': '379', 'last_page': '84'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11337', 'display_name': 'Neuroimmune Interaction in Psychiatric Disorders', 'score': 0.8287, 'subfield': {'id': 'https://openalex.org/subfields/2803', 'display_name': 'Biological Psychiatry'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11337', 'display_name': 'Neuroimmune Interaction in Psychiatric Disorders', 'score': 0.8287, 'subfield': {'id': 'https://openalex.org/subfields/2803', 'display_name': 'Biological Psychiatry'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10529', 'display_name': 'Effects of Stress on Brain Function and Health', 'score': 0.821, 'subfield': {'id': 'https://openalex.org/subfields/2802', 'display_name': 'Behavioral Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11071', 'display_name': 'Molecular Mechanisms of Depression Treatment Strategies', 'score': 0.8136, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mechanism-of-action', 'display_name': 'Mechanism of action', 'score': 0.5917624}, {'id': 'https://openalex.org/keywords/antidepressant-treatment', 'display_name': 'Antidepressant Treatment', 'score': 0.554554}, {'id': 'https://openalex.org/keywords/neurobiological-mechanisms', 'display_name': 'Neurobiological Mechanisms', 'score': 0.515632}, {'id': 'https://openalex.org/keywords/modulation', 'display_name': 'Modulation (music)', 'score': 0.4670374}], 'concepts': [{'id': 'https://openalex.org/C37000724', 'wikidata': 'https://www.wikidata.org/wiki/Q50430226', 'display_name': 'Serotonergic', 'level': 4, 'score': 0.9623097}, {'id': 'https://openalex.org/C2779177272', 'wikidata': 'https://www.wikidata.org/wiki/Q76560', 'display_name': 'Antidepressant', 'level': 3, 'score': 0.8695396}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.6399747}, {'id': 'https://openalex.org/C2776120743', 'wikidata': 'https://www.wikidata.org/wiki/Q3271540', 'display_name': 'Mechanism of action', 'level': 3, 'score': 0.5917624}, {'id': 'https://openalex.org/C89611455', 'wikidata': 'https://www.wikidata.org/wiki/Q6804646', 'display_name': 'Mechanism (biology)', 'level': 2, 'score': 0.5296354}, {'id': 'https://openalex.org/C2780791683', 'wikidata': 'https://www.wikidata.org/wiki/Q846785', 'display_name': 'Action (physics)', 'level': 2, 'score': 0.50753677}, {'id': 'https://openalex.org/C123079801', 'wikidata': 'https://www.wikidata.org/wiki/Q750240', 'display_name': 'Modulation (music)', 'level': 2, 'score': 0.4670374}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.42758694}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3934656}, {'id': 'https://openalex.org/C2775864247', 'wikidata': 'https://www.wikidata.org/wiki/Q167934', 'display_name': 'Serotonin', 'level': 3, 'score': 0.38407212}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.29941416}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.19256073}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.16394654}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.1382468}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.099736184}, {'id': 'https://openalex.org/C2781161787', 'wikidata': 'https://www.wikidata.org/wiki/Q48360', 'display_name': 'Hippocampus', 'level': 2, 'score': 0.065161765}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C24890656', 'wikidata': 'https://www.wikidata.org/wiki/Q82811', 'display_name': 'Acoustics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000928', 'descriptor_name': 'Antidepressive Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009638', 'descriptor_name': 'Norepinephrine', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D012701', 'descriptor_name': 'Serotonin', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015116', 'descriptor_name': '5,7-Dihydroxytryptamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015116', 'descriptor_name': '5,7-Dihydroxytryptamine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000928', 'descriptor_name': 'Antidepressive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003891', 'descriptor_name': 'Desipramine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003891', 'descriptor_name': 'Desipramine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009638', 'descriptor_name': 'Norepinephrine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011919', 'descriptor_name': 'Rats, Inbred Strains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012701', 'descriptor_name': 'Serotonin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4034853', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.84, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2899084033', 'https://openalex.org/W2806574399', 'https://openalex.org/W2433046558', 'https://openalex.org/W2398080393', 'https://openalex.org/W2385705390', 'https://openalex.org/W2185247125', 'https://openalex.org/W2163250198', 'https://openalex.org/W2135759292', 'https://openalex.org/W2081078008', 'https://openalex.org/W2035266273'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2418446309', 'counts_by_year': [], 'updated_date': '2024-09-15T09:25:50.864822', 'created_date': '2016-06-24'}