Publication Information

{'id': 'https://openalex.org/W2414799073', 'doi': 'https://doi.org/10.1385/0-89603-298-1:167', 'title': 'Mass Measurement of Key Phosphoinositide Cycle Intermediates', 'display_name': 'Mass Measurement of Key Phosphoinositide Cycle Intermediates', 'publication_year': 2003, 'publication_date': '2003-11-14', 'ids': {'openalex': 'https://openalex.org/W2414799073', 'doi': 'https://doi.org/10.1385/0-89603-298-1:167', 'mag': '2414799073', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7655553'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1385/0-89603-298-1:167', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463399', 'display_name': 'Humana Press eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310315801', 'host_organization_name': 'Humana Press', 'host_organization_lineage': ['https://openalex.org/P4310315801'], 'host_organization_lineage_names': ['Humana Press'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5044018474', 'display_name': 'R. A. John Challiss', 'orcid': 'https://orcid.org/0000-0001-5506-2848'}, 'institutions': [{'id': 'https://openalex.org/I153648349', 'display_name': 'University of Leicester', 'ror': 'https://ror.org/04h699437', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I153648349']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'R.A. John Challiss', 'raw_affiliation_strings': ['Department of Cell Physiology and Pharmacology, University of Leicester, UK'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Physiology and Pharmacology, University of Leicester, UK', 'institution_ids': ['https://openalex.org/I153648349']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5044018474'], 'corresponding_institution_ids': ['https://openalex.org/I153648349'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 74, 'max': 76}, 'biblio': {'volume': None, 'issue': None, 'first_page': '167', 'last_page': '176'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13415', 'display_name': 'Calcium signaling and nucleotide metabolism', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10169', 'display_name': 'Protein Kinase Regulation and GTPase Signaling', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/second-messenger-system', 'display_name': 'Second messenger system', 'score': 0.9326134}, {'id': 'https://openalex.org/keywords/phosphoinositide-phospholipase-c', 'display_name': 'Phosphoinositide phospholipase C', 'score': 0.74069816}, {'id': 'https://openalex.org/keywords/gq-alpha-subunit', 'display_name': 'Gq alpha subunit', 'score': 0.55685854}, {'id': 'https://openalex.org/keywords/inositol-trisphosphate', 'display_name': 'Inositol trisphosphate', 'score': 0.49868464}, {'id': 'https://openalex.org/keywords/inositol-trisphosphate-receptor', 'display_name': 'Inositol trisphosphate receptor', 'score': 0.47185752}, {'id': 'https://openalex.org/keywords/phosphatidylinositol-4,5-bisphosphate', 'display_name': 'Phosphatidylinositol 4,5-bisphosphate', 'score': 0.46814802}, {'id': 'https://openalex.org/keywords/inositol-phosphate', 'display_name': 'Inositol phosphate', 'score': 0.4350404}, {'id': 'https://openalex.org/keywords/phospholipase-d', 'display_name': 'Phospholipase D', 'score': 0.4243032}], 'concepts': [{'id': 'https://openalex.org/C163235415', 'wikidata': 'https://www.wikidata.org/wiki/Q899814', 'display_name': 'Second messenger system', 'level': 3, 'score': 0.9326134}, {'id': 'https://openalex.org/C2780610907', 'wikidata': 'https://www.wikidata.org/wiki/Q2273248', 'display_name': 'Phosphatidylinositol', 'level': 3, 'score': 0.8472879}, {'id': 'https://openalex.org/C36020004', 'wikidata': 'https://www.wikidata.org/wiki/Q106951674', 'display_name': 'Diacylglycerol kinase', 'level': 4, 'score': 0.7893672}, {'id': 'https://openalex.org/C2777427919', 'wikidata': 'https://www.wikidata.org/wiki/Q407997', 'display_name': 'Inositol', 'level': 3, 'score': 0.7429701}, {'id': 'https://openalex.org/C78297661', 'wikidata': 'https://www.wikidata.org/wiki/Q10760862', 'display_name': 'Phosphoinositide phospholipase C', 'level': 4, 'score': 0.74069816}, {'id': 'https://openalex.org/C2778597717', 'wikidata': 'https://www.wikidata.org/wiki/Q420248', 'display_name': 'Phospholipase C', 'level': 3, 'score': 0.6912967}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5670818}, {'id': 'https://openalex.org/C66135807', 'wikidata': 'https://www.wikidata.org/wiki/Q24726231', 'display_name': 'Gq alpha subunit', 'level': 4, 'score': 0.55685854}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.51293874}, {'id': 'https://openalex.org/C2781387506', 'wikidata': 'https://www.wikidata.org/wiki/Q138145', 'display_name': 'Inositol trisphosphate', 'level': 4, 'score': 0.49868464}, {'id': 'https://openalex.org/C2778918659', 'wikidata': 'https://www.wikidata.org/wiki/Q186915', 'display_name': 'Phospholipid', 'level': 3, 'score': 0.48715183}, {'id': 'https://openalex.org/C152624196', 'wikidata': 'https://www.wikidata.org/wiki/Q418917', 'display_name': 'Inositol trisphosphate receptor', 'level': 4, 'score': 0.47185752}, {'id': 'https://openalex.org/C2777853560', 'wikidata': 'https://www.wikidata.org/wiki/Q3083814', 'display_name': 'Phosphatidylinositol 4,5-bisphosphate', 'level': 4, 'score': 0.46814802}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.45765364}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4488353}, {'id': 'https://openalex.org/C2778618036', 'wikidata': 'https://www.wikidata.org/wiki/Q2878809', 'display_name': 'Inositol phosphate', 'level': 4, 'score': 0.4350404}, {'id': 'https://openalex.org/C6182249', 'wikidata': 'https://www.wikidata.org/wiki/Q700007', 'display_name': 'Phospholipase D', 'level': 3, 'score': 0.4243032}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.4207918}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3363313}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.30270785}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.29331332}, {'id': 'https://openalex.org/C195794163', 'wikidata': 'https://www.wikidata.org/wiki/Q420877', 'display_name': 'Protein kinase C', 'level': 3, 'score': 0.2537248}, {'id': 'https://openalex.org/C80631254', 'wikidata': 'https://www.wikidata.org/wiki/Q407438', 'display_name': 'G protein', 'level': 3, 'score': 0.16604438}], 'mesh': [{'descriptor_ui': 'D010716', 'descriptor_name': 'Phosphatidylinositols', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D015290', 'descriptor_name': 'Second Messenger Systems', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002477', 'descriptor_name': 'Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002477', 'descriptor_name': 'Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008722', 'descriptor_name': 'Methods', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010716', 'descriptor_name': 'Phosphatidylinositols', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010716', 'descriptor_name': 'Phosphatidylinositols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011869', 'descriptor_name': 'Radioligand Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1385/0-89603-298-1:167', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463399', 'display_name': 'Humana Press eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310315801', 'host_organization_name': 'Humana Press', 'host_organization_lineage': ['https://openalex.org/P4310315801'], 'host_organization_lineage_names': ['Humana Press'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7655553', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.43, 'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 9, 'referenced_works': ['https://openalex.org/W1615484104', 'https://openalex.org/W1815056551', 'https://openalex.org/W1980166477', 'https://openalex.org/W1988256926', 'https://openalex.org/W1994794688', 'https://openalex.org/W2057015841', 'https://openalex.org/W2066935607', 'https://openalex.org/W2144106671', 'https://openalex.org/W2259594190'], 'related_works': ['https://openalex.org/W429778924', 'https://openalex.org/W2387957150', 'https://openalex.org/W2185380343', 'https://openalex.org/W2112638018', 'https://openalex.org/W2090798921', 'https://openalex.org/W2090575139', 'https://openalex.org/W2050923205', 'https://openalex.org/W2008575709', 'https://openalex.org/W165163710', 'https://openalex.org/W149292485'], 'abstract_inverted_index': {'The': [0], 'phosphoinositide': [1, 69], 'cycle': [2], 'is': [3], 'now': [4], 'established': [5], 'as': [6], 'a': [7, 12], 'major': [8], 'pathway': [9], 'by': [10], 'which': [11], 'variety': [13], 'of': [14, 34], 'hormones,': [15], 'neurotransmitters,': [16], 'and': [17, 25, 56, 65], 'other': [18], 'signaling': [19], 'molecules': [20], 'can': [21], 'generate': [22, 48], 'second': [23, 50], 'messengers': [24], 'thus': [26], 'affect': [27], 'the': [28, 40], 'intracellular': [29], 'milieu': [30], '(1).': [31], 'Receptor-mediated': [32], 'activation': [33], 'membrane-associated': [35], 'enzymic': [36], 'activities': [37], 'act': [38], 'on': [39], 'minor': [41], 'membrane': [42], 'phospholipid': [43], 'phosphatidylinositol': [44, 66], '4,5-bisphosphate': [45], '[PtdIns(4,5)P2]': [46], 'to': [47], 'three': [49], 'messenger': [51], 'molecules:': [52], 'inositol': [53, 59], '1,4,5-trisphosphate': [54], '[Ins(1,4,5)P3]': [55], '1,2-diacylglycerol': [57], 'via': [58, 68], 'phospholipid-specific': [60], 'phospholipase': [61], 'C': [62], '(PI-PLC)': [63], 'activity,': [64], '3,4,5-trisphosphate': [67], '3-kinase': [70], 'activity': [71], '(2).': [72]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2414799073', 'counts_by_year': [], 'updated_date': '2024-12-10T22:43:45.496040', 'created_date': '2016-06-24'}