Spontaneous and quinine induced hypoglycaemia in severe falciparum malaria.

Name: Work Video:
Duration: 3 min 30 s
Description: Four of 21 patients with cerebral malaria developed hypoglycaemia, defined as plasma glucose concentration below 40 mg/dl (2.2 mmol/l). Two patients had spontaneous hypoglycaemia at admission and the other two developed it subsequent to quinine therapy. All recovered with continuous intravenous glucose infusion. Spontaneous hypoglycaemia in malaria has not earlier been reported from India.
Arya Tv; Prasad Rn; Suwas Bhandari; R Awasthi
{'id': 'https://openalex.org/W2411943907', 'doi': None, 'title': 'Spontaneous and quinine induced hypoglycaemia in severe falciparum malaria.', 'display_name': 'Spontaneous and quinine induced hypoglycaemia in severe falciparum malaria.', 'publication_year': 1989, 'publication_date': '1989-01-01', 'ids': {'openalex': 'https://openalex.org/W2411943907', 'mag': '2411943907', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2669291'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2669291', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5062497062', 'display_name': 'Arya Tv', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I45294948', 'display_name': 'Post Graduate Institute of Medical Education and Research', 'ror': 'https://ror.org/009nfym65', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I45294948']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Arya Tv', 'raw_affiliation_strings': ['Department of Internal Medicine, Postgraduate Institute of medical education and research, Chandigarh, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Postgraduate Institute of medical education and research, Chandigarh, India', 'institution_ids': ['https://openalex.org/I45294948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008681382', 'display_name': 'Prasad Rn', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Prasad Rn', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084793512', 'display_name': 'Suwas Bhandari', 'orcid': 'https://orcid.org/0000-0002-8625-4700'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Bhandari S', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5008537464', 'display_name': 'R Awasthi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Awasthi R', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.526, 'has_fulltext': False, 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.620057, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 69, 'max': 71}, 'biblio': {'volume': '41', 'issue': '1', 'first_page': '73', 'last_page': '5'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.979, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.979, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/quinine', 'display_name': 'Quinine', 'score': 0.96606445}, {'id': 'https://openalex.org/keywords/cerebral-malaria', 'display_name': 'Cerebral Malaria', 'score': 0.83804715}, {'id': 'https://openalex.org/keywords/severe-malaria', 'display_name': 'Severe Malaria', 'score': 0.42461234}], 'concepts': [{'id': 'https://openalex.org/C2777617192', 'wikidata': 'https://www.wikidata.org/wiki/Q189522', 'display_name': 'Quinine', 'level': 3, 'score': 0.96606445}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.8870324}, {'id': 'https://openalex.org/C2908793570', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Cerebral Malaria', 'level': 4, 'score': 0.83804715}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.7669548}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6183194}, {'id': 'https://openalex.org/C2780668416', 'wikidata': 'https://www.wikidata.org/wiki/Q202758', 'display_name': 'Hypoglycemia', 'level': 3, 'score': 0.6012042}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.47250068}, {'id': 'https://openalex.org/C3019824283', 'wikidata': 'https://www.wikidata.org/wiki/Q353172', 'display_name': 'Protozoal disease', 'level': 3, 'score': 0.4364719}, {'id': 'https://openalex.org/C2910455041', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Severe Malaria', 'level': 4, 'score': 0.42461234}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.3491042}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3490494}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.19676393}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.06341478}], 'mesh': [{'descriptor_ui': 'D007003', 'descriptor_name': 'Hypoglycemia', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D011803', 'descriptor_name': 'Quinine', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007003', 'descriptor_name': 'Hypoglycemia', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D007003', 'descriptor_name': 'Hypoglycemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007194', 'descriptor_name': 'India', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011803', 'descriptor_name': 'Quinine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2669291', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.86, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2413447338', 'https://openalex.org/W2411943907', 'https://openalex.org/W2411241726', 'https://openalex.org/W2402970964', 'https://openalex.org/W2164965375', 'https://openalex.org/W2077977733', 'https://openalex.org/W2047039236', 'https://openalex.org/W1985118431', 'https://openalex.org/W1818269711', 'https://openalex.org/W177741998'], 'abstract_inverted_index': {'Four': [0], 'of': [1], '21': [2], 'patients': [3, 20], 'with': [4, 38], 'cerebral': [5], 'malaria': [6, 46], 'developed': [7, 30], 'hypoglycaemia,': [8], 'defined': [9], 'as': [10], 'plasma': [11], 'glucose': [12, 41], 'concentration': [13], 'below': [14], '40': [15], 'mg/dl': [16], '(2.2': [17], 'mmol/l).': [18], 'Two': [19], 'had': [21], 'spontaneous': [22], 'hypoglycaemia': [23, 44], 'at': [24], 'admission': [25], 'and': [26], 'the': [27], 'other': [28], 'two': [29], 'it': [31], 'subsequent': [32], 'to': [33], 'quinine': [34], 'therapy.': [35], 'All': [36], 'recovered': [37], 'continuous': [39], 'intravenous': [40], 'infusion.': [42], 'Spontaneous': [43], 'in': [45], 'has': [47], 'not': [48], 'earlier': [49], 'been': [50], 'reported': [51], 'from': [52], 'India.': [53]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2411943907', 'counts_by_year': [], 'updated_date': '2024-12-08T10:54:56.908362', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
