Publication Information

{'id': 'https://openalex.org/W2413447338', 'doi': 'https://doi.org/10.4269/ajtmh.1983.32.456', 'title': 'Red Cell Quinine Concentrations in Falciparum Malaria', 'display_name': 'Red Cell Quinine Concentrations in Falciparum Malaria', 'publication_year': 1983, 'publication_date': '1983-05-01', 'ids': {'openalex': 'https://openalex.org/W2413447338', 'doi': 'https://doi.org/10.4269/ajtmh.1983.32.456', 'mag': '2413447338', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/6344670'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.4269/ajtmh.1983.32.456', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100045985', 'display_name': 'American Journal of Tropical Medicine and Hygiene', 'issn_l': '0002-9637', 'issn': ['0002-9637', '1476-1645'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315658', 'host_organization_name': 'American Society of Tropical Medicine and Hygiene', 'host_organization_lineage': ['https://openalex.org/P4310315658'], 'host_organization_lineage_names': ['American Society of Tropical Medicine and Hygiene'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084217335', 'display_name': 'Nicholas J. White', 'orcid': 'https://orcid.org/0000-0002-1897-1978'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Nicholas J. White', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105936906', 'display_name': 'Sornchai Looareesuwan', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Sornchai Looareesuwan', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5110792796', 'display_name': 'Kamolrat Silamut', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kamolrat Silamut', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.731, 'has_fulltext': False, 'cited_by_count': 27, 'citation_normalized_percentile': {'value': 0.898628, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '32', 'issue': '3', 'first_page': '456', 'last_page': '460'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 0.9863, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10211', 'display_name': 'Computational Drug Discovery Methods', 'score': 0.9481, 'subfield': {'id': 'https://openalex.org/subfields/1703', 'display_name': 'Computational Theory and Mathematics'}, 'field': {'id': 'https://openalex.org/fields/17', 'display_name': 'Computer Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/quinine', 'display_name': 'Quinine', 'score': 0.9800012}, {'id': 'https://openalex.org/keywords/cerebral-malaria', 'display_name': 'Cerebral Malaria', 'score': 0.8644713}, {'id': 'https://openalex.org/keywords/red-cell', 'display_name': 'Red Cell', 'score': 0.67468107}], 'concepts': [{'id': 'https://openalex.org/C2777617192', 'wikidata': 'https://www.wikidata.org/wiki/Q189522', 'display_name': 'Quinine', 'level': 3, 'score': 0.9800012}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.8749176}, {'id': 'https://openalex.org/C2908793570', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Cerebral Malaria', 'level': 4, 'score': 0.8644713}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.8231411}, {'id': 'https://openalex.org/C2777208419', 'wikidata': 'https://www.wikidata.org/wiki/Q4347672', 'display_name': 'Red Cell', 'level': 2, 'score': 0.67468107}, {'id': 'https://openalex.org/C2776557347', 'wikidata': 'https://www.wikidata.org/wiki/Q37187', 'display_name': 'Red blood cell', 'level': 2, 'score': 0.6266812}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.52213603}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.4158377}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.38453877}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.35885012}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3274885}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.32431692}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3232716}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.096259385}], 'mesh': [{'descriptor_ui': 'D004912', 'descriptor_name': 'Erythrocytes', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D011803', 'descriptor_name': 'Quinine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001927', 'descriptor_name': 'Brain Diseases', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D001927', 'descriptor_name': 'Brain Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004912', 'descriptor_name': 'Erythrocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008288', 'descriptor_name': 'Malaria', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011803', 'descriptor_name': 'Quinine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011803', 'descriptor_name': 'Quinine', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.4269/ajtmh.1983.32.456', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100045985', 'display_name': 'American Journal of Tropical Medicine and Hygiene', 'issn_l': '0002-9637', 'issn': ['0002-9637', '1476-1645'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315658', 'host_organization_name': 'American Society of Tropical Medicine and Hygiene', 'host_organization_lineage': ['https://openalex.org/P4310315658'], 'host_organization_lineage_names': ['American Society of Tropical Medicine and Hygiene'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/6344670', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.88}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2443559567', 'https://openalex.org/W2436912489', 'https://openalex.org/W2422956653', 'https://openalex.org/W2413447338', 'https://openalex.org/W2411241726', 'https://openalex.org/W2409312553', 'https://openalex.org/W2408345149', 'https://openalex.org/W2129015658', 'https://openalex.org/W1998937714', 'https://openalex.org/W1974395090'], 'abstract_inverted_index': {'Red': [0, 25, 94], 'cell': [1, 26, 95], 'concentrations': [2], 'of': [3, 61, 77, 104, 111], 'quinine': [4, 27, 96], 'were': [5, 31], 'measured': [6], 'in': [7, 11, 16, 40, 52], 'cerebral': [8, 41], 'malaria': [9, 14, 42], 'and': [10, 20, 43, 107], 'uncomplicated': [12, 45, 54], 'falciparum': [13], 'both': [15], 'the': [17, 35, 68, 73, 87, 102, 109], 'acute': [18, 53], 'stage': [19], '1': [21], 'month': [22], 'after': [23], 'recovery.': [24], 'elimination': [28], 'half': [29, 38], 'times': [30, 39], 'significantly': [32], 'shorter': [33], 'than': [34], 'corresponding': [36], 'plasma': [37], 'convalescent': [44], 'cases': [46, 55], '(P': [47, 56, 91], '<': [48], '0.001),': [49], 'but': [50], 'not': [51], '=': [57, 92], '0.12).': [58], 'The': [59], 'ratio': [60, 82], 'red': [62], 'cell:plasma': [63], 'concentration': [64, 97], 'fell': [65], 'progressively': [66], 'from': [67], '2nd': [69], 'day': [70, 75], '(0.49)': [71], 'to': [72, 101, 108], '6th': [74], '(0.26)': [76], 'treatment.': [78], 'On': [79], 'admission': [80], 'this': [81], 'was': [83], 'positively': [84], 'correlated': [85], 'with': [86], 'blood': [88], 'parasite': [89], 'count': [90], '0.02).': [93], 'may': [98], 'be': [99], 'relevant': [100], 'assessment': [103], 'drug': [105], 'resistance,': [106], 'design': [110], 'treatment': [112], 'regimens.': [113]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2413447338', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-08T20:47:27.262395', 'created_date': '2016-06-24'}