Title: [Research progress of protein tyrosine phosphatase SHP-2].
Abstract:The Src homology-2 domain-containing phosphatase SHP-2 encoded by PTPN11 is an essential component in several signaling pathways.Different types of mutation in SHP-2 have been confirmed in several typ...The Src homology-2 domain-containing phosphatase SHP-2 encoded by PTPN11 is an essential component in several signaling pathways.Different types of mutation in SHP-2 have been confirmed in several types of leukemia and solid tumors. Elucidation of the events underlying Shp2-evoked transformation may provide new insights into the novel targets for anti-cancer therapy.Read More
Publication Year: 2012
Publication Date: 2012-09-01
Language: en
Type: review
Indexed In: ['pubmed']
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