Title: The Effect of Prestorage Leucocyte Filtration on the Quality and Complement Activation of Fresh Plasma
Abstract: Objective To investigate the effect of prestorage leucocyte filtration on the quality and complement activation of fresh plasmas.Methods Twenty leucocyte filtrated fresh plasmas were produced by leucocyte filter.Samples were taken before and post filtration,contents of coagulation factor Ⅷ(FⅧ),fibrinogen(FIB) and complement C3a,C5a were analysed respectively.Results The contents of FⅧ,FIB and C5a in post filtered plasmas had no statistical difference compared with that of pre-filtered plasmas,but the content of C3a in post filtered plasmas was higher than that of pre-filtered plasmas.Conclusion Prestorage filtration of plasma activates the complement cascade reaction but not influence the quality of fresh plasma.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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