Title: Curative Effect on Dendrobium Soup Combined Menotrophin( HMG) Treatment of Clomiphine Resistance Polycystic Ovary Syndrome Infertility
Abstract: Objective: To observe the curative effect that dendrobium soup combined Menotrophin( HMG) treatment for clomiphine resistance polycystic ovary syndrome infertility,and discuss the echanism of action. Methods: 60 cases of clomiphine resistance polycystic ovary syndrome infertility patients were randomly divided into treatment group( dendrobium soup + HMG treatment) and control group( HMG treatment used alone),each group of 30 patients,with continuous observation of three menstrual cycles,calculated the ovulation rate and pregnancy rate of each group,tested follicular average diameter before ovulation、minimum and maximum diameter difference、endometrial thickness and the level of menstrual 22 days serum testosterone( T) 、 follicle stimulating hormone( FSH) 、luteinizing hormone( LH). Results: In the treatment group,23 cases were ovulated( 76. 7%),13 cases were pregnant( 43. 3%),and in control group,21 cases were ovulated( 70%),7 cases were pregnant( 23. 3%),the ovulation rates of twogroups were similar( P 0. 05),the pregnancy rate of treatment group was higher than that of control group' s( P 0. 05); The follicular average diameters before ovulation of two groups were close,had no significant difference( P 0. 05); compared with control group,the difference of follicular minimum and maximum diameters before ovulation in the treatment group were smaller,and endometrial thickness before ovulation was higher,the difference was obvious( P 0. 05); Compared the two groups' levels of LH and FSH after treatment,and compared the level before treatment and after treatment in each groups,the difference was not obvious( P 0. 05); but the level of T in treatment group after treatment was reduced than that before treatment( P 0. 05); Compared the T levels of two groups after treatment,the T level of treatment group was significantly lower than the control group( P 0. 05). Conclusion: The treatment has good curative effect,it can promote the follicular growth,increase endometrial thickness,and lower testosterone levels,so as to improve the pregnancy rate.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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