Title: The difference of mRNA expression of multiple hematopoietic growth factors between human umbilical cord blood stromal sells and bone marrow stromal cells
Abstract: Objective To study the difference of mRNA expression level of hematopoietic growth factors between human umbilical cord stromal cells and bone marrow stromal cells in vitro.Methods We detected the mRNA expression level of GM-CSF,SCF,TPO of human umbilical cord blood and bone marrow stromal cells being cultured for 28d in vitro.Results Human umbilical cord blood stromal cells secrete more TPO and less SCF,GM-SCF than bone marrow stromal cells.Conclusion Human umbilical cord blood stromal cells and bone marrow stromal cells could expressi mRNA of hematopoietic growth factors such as GM-CSF,SCF,TPO.They all may regulate hematopoiesis through secreting multiple hematopoietic growth factors.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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