Title: A Study on the Synthesis of l-Pheny 1-3-methy 1-5-pyrazolone
Abstract: l-Phenyl-3-methyl-5-pyrazoIone was synthesized by the reaction of ethyl acetoacetate and phenyl hydrazine in ethanol. The optimum conditions were obtained by single factor orthogonal design method, the molar ratio of ethyl acetoacetate and phenyl hydrazine was 1.05:1, 50ml ethanol(anhydrous), reaction temperature 70 ℃, reaction time 2 hours and then refluxing for 7 hours, the yield was 90.9%, the purity was 99.0%.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot