Title: Study on the renal protective effect of Atorvastatin on patients with diabetic nephropathy and coronary heart disease
Abstract: Objective To investigate the renal protective effect of Atorvastatin on patients with diabetic nephropathy and coronary heart disease. Methods From January 2012 to April 2013 in the People's Hospital of Pingshan County, Hebei Province, 71 patients with diabetic nephropathy and coronary heart disease were selected as research subjects, 35 patients of the control group were treated with conventional therapy, 36 patients of the observation group were added Atorvastatin, the blood glucose, blood lipid levels and renal function of two groups before and after treatment were compared, the observed indicators were fasting blood glucose(FBG), 2 h postprandial blood glucose(2 h PG), serum cholesterol(TC), triglyceride(TG), low density lipoprotein cholesterol(LDL-C), high density lipoprotein cholesterol(HDL-C) and serum creatinine(Scr), urinary albumin excretion rate(UAER), urinary albumin(mALB). Results After treatment, the patient′s blood glucose levels were controlled in the normal, the difference was not statistically significant between two groups(P 0.05); after treatment, the TC, TG, LDL-C, UAER of two groups were significantly lower, mALB significantly increased, and the observation group improved more obviously, the differences were statistically significant between the two groups(P 0.05). Conclusion Atorvastatin on patients with diabetic nephropathy and coronary heart disease has a significant protective effect of kidney, and can delay the development of renal damage, which helps to improve the quality of life of patients.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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