Title: Percutaneous ablation for small hepatocellular carcinoma equal to or less than 2 cm in diameter
Abstract: Objective To investigate the therapeutic effects of percutaneous ablation for hepatocellular carcinoma (HCC) which the diameter was less than 2 cm.Methods Thirty-three cases of pathologically conformed HCC were treated with percutaneous microwave ablation (MWA) or percutaneous ethanol injection (PEI).Results The complete ablation rate was 93.9%,the local recurrence and distant recurrence rates were 9.1% and 33.3%,respectively.One,two-,and three-year disease-free survival rates were 62.6%,62.6% and 62.6%,respectively and overall survival rates were 84.0%、74.5% and 63.9%,respectively.By univariate analysis,only pre-ablation α-fetoprotein (AFP) level was significantly related to recurrence-free survival,while AFP level and distant recurrence were significantly related to overall survival. In multivariate analysis,AFP level and distant recurrence were independent risk factors to overall survival.Conclusion Percutaneous ablation is capable of eradicating HCC which the size is less than 2 cm.Pre-ablation AFP level and post-treatment distant recurrence are significantly related to prognosis.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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