Title: Antihypertensive effect of“Huoxue Qianyang Formula”on prothrombotic state in patients with hypertension
Abstract: Objective To investigate the antihypertensive effect ofHuoxue Qianyang Formulaon prothrombotic state(PTS)in patients with hypertension.Methods Ninty-nine cases with hypertension of blood stasis and yang hyperactivity pattern were randomized into group A(treated with Chinese medicine),group B(treated with Amlodipine Tablet and Chinese medicine),control group(treated with Amlodipine Tablet),with 33cases in each group,with the course of 8weeks.The blood pressure,clinical symptoms and levels of blood plasma vWF,DD and Fig were observed.Results ①After 8weeks treatment,96cases were finished this clinical observation.Thirty-one cases in group A,32cases in group B and 33cases in control group.② There were significant differences in systolic pressure,diastolic pressure and clinical symptoms among the three groups between before treatment and 28th day after treatment or between before treatment and 56th day after treatment(P0.05).On the 28th day and 56th day,no significant difference was found in systolic pressure,diastolic pressure and clinical symptoms among the groups(P0.05).After treatment,there were significant differences in systolic pressure,diastolic pressure and clinical symptoms between treatment groups and control group at the 28th day and 56th day(P0.05).there were significant differences in systolic pressure,diastolic pressure and clinical symptoms between the two treatment groups at the 28th day and 56th day after treatment respectively,and the therapeutic effect of group B was better than the group A(P0.05).③ The levels of vWF,DD and Fig before treatment were different from that of the 56th day after treatment among the three groups(P0.05);at the 56th day,there were significant difference in the levels of vWF,DD and Fig between treatment groups and control group(P0.05);significant differences were found in the levels of vWF,DD and Fig between the two treatment groups,and the therapeutic effect of group B was better than the group A(P0.05). Conclusion CombinedHuoxue Qianyang Formulaand Amlodipine Tablet can lower the blood pressure,alleviate clinical symptoms,improve PTS in patients with hypertension of blood stasis and yang hyperactivity pattern.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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