Title: Expression of vascular endothelial growth factor A and C in cholangiocarcinoma and their significance
Abstract: [Objective] To investigate the relationship between expression and significance VEGF and VEGF-C in cholangiocarcinoma.[Methods] The expression of VEGF and VEGF-C was determined by immunohistoche-mical method in the 49 samples of cholangiocarcinoma.[Results] The rates of positive expression VEGF and VEGF-C were 65.3% and 69.4% in cholangiocarcinoma.The expression of VEGF and VEGF-C protein was correlated with tumor invasion,differentiation and lymph node metastasis.VEGF expression was significantly correlated with VEGF-C expression in hepatocellular carcinoma(P 0.01).[Conclusion] VEGF and VEGF-C played a role in invasion and metastasis of cholangiocarcinoma.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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