Title: Treatment of 254 Cases of Acne Vulgaris with Cuoyanling
Abstract: Objective To survey the therapeutic effectiveness and safety rate of cuoyanling No.1No.2 prepared by ourselves in the treatment of acne vulgaris. Methods 359 patients with acne vulgaris were randomly divided into three groups: the trial group1(n=116),trial group 2(n=138) and control group(n=105).Patients of the trial group 1 were treated with cuoyanling NO.1(2 g of metronidazole and 0.5 g of chlorompenicol dissolved in 100 mL of 75% ethanol)locally applied onto the eruptions 3-4 times a day.Patients of the trial group 2 were treated with cuoyanling NO.1 3 times a day during daytime and once a day with cuoyanling NO.2(30 g of 2% sulphur cream frost containing 1.4 g of powdered metronidazode) at night predormitally.The drugs were painted or smeared onto the lesions locally.Patients of the control group were treated only with 2% sulphur cream frost 3-4 times a day.All patients were asked to wash their faces before treatment.The course of treatment in all 3 groups lasted 4 weeks.Changes in the lesions including comedones,inflammatory papules,pustules and nodules as well as adverse reactions were kept under careful observation. Results The overall effective rate in patients of the trial group 1 was 87.1%: 32 patients(27.6%) were basically cured,69 patients(59.5%) had excellent therapeutic effects and 12(10.3%) showed improvement.The overall effective in patients of the trial group 2 was 93.5%: 41 pationts(29.7%) were basically cured,88 patients(63.8%) had excellents therapeutic effects and 7(5.1%) showed improvement.The overall effective rate in patients of the control group was 7.7%: 3 patients(2.9%) were basically cured,5 patients(4.8%)showed excellent therapeutic effects and 25(23.8%)showed improvement.No major adverse reactions were encountered in patients of all 3 groups. Conclusion Cuoyanling was shown to be safe and effective in the treatment of acne vulgaris.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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