Title: Clinical study of large arterial elasticity in patients with essential hypertension
Abstract: Objective:To explore the change of large arterial elasticity in essential hypertensive patients and the influencing factors.Method:Automatic pulse wave velocity measuring system was applied to examine carotid-femoral pulse wave velocity (CFPWV) as an index reflecting elasticity of large arteries. 114 healthy subjects and 476 hypertensive patients were recruited in the study.Result:CFPWV was significantly higher in the hypertensive patients group than healthy subjects group (P0.01). CFPWV increased with age in both groups (P0.01). A stepwise multiple regressive analysis demonstrated that age was significantly associated with CFPWV in healthy subjects. Age, systolic blood pressure and heart rate were positively and independently related to CFPWV in hypertensive patients.Conclusion:Advanced age contributes to the degeneration of the large arterial elasticity, high blood pressure accelerates the process. Age, systolic blood pressure and heart rate have close relationship with large arterial elasticity of hypertensive patients. PWV could be used as a noninvasive, simple measurement to evaluate large arterial elasticity of hypertensive patients.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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