Title: A Nuclear Matrix Member-topoisomerase II and Tumor Multidrug Resistance
Abstract:DNA topoisomerase,one kind of nuclear matrix is a kind of one of nuclear enzyme that can modify DNA topology.For it plays a important role in DNA replication and transcription,it becomes the target of...DNA topoisomerase,one kind of nuclear matrix is a kind of one of nuclear enzyme that can modify DNA topology.For it plays a important role in DNA replication and transcription,it becomes the target of some anticancer drugs.The same as other anticancer drugs,DNA topoisomerase has to face the problem of drug resistance.This article is mainly to illustrate the relationship between DNA topoisomerase II and the mechanism of tumor drug resistance.Read More
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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