Title: Study on the Tumor Cells Anti-Proliferation Effect of PEG-IFNα2b
Abstract: AIM To study the anti tumor effect of recombination IFNα2b and PEG IFNα2b in vitro . METHODS MTT assay was applied to investigate the tumor cells growth inhibitory effect by different concentrations of recombination IFNα2b and PEG IFNα2b. RESULTS The growth of SMMC 7721, K562, HeLa, KB and BGC cells were all inhibited by various concentration of IFNα2b and PEG IFNα2b at dose 500 ng/ml, 50 ng/ml, 5 ng/ml, 0.5 ng/ml. CONCLUSION PEG IFNα2b was more effective than IFN to inhibit the growth of tumor cells.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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