Title: A Comparative Study with Multi-Slice CT Perfusion Imaging:Before And After Interventional Therapy in Acute Cerebral Ischemia
Abstract: Objective To evaluate the role of multi-slice CT perfusion(MSCTP) in monitoring hemodynamic changes in the patients with acute cerebral ischemia before and after interventional therapy.Methods 48 patients with acute cerebral ischemia were included in this prospective study.MSCTP was performed before and after interventional therapy during the injection of 50 ml of contrast material.Perfusion coverage was adjusted according to vascular territory of interest.Mean cerebral blood volume(CBV),cerebral blood flow(CBF),mean transit time(MTT) were calculated for different vascular territories in both hemisphere,and so the CBF ratios(RCBF),CBV ratios(RCBV)and MTT ratios(RMTT)on ischemic marginal region and ischemic central region.Results The RCBF was increased significantly on ischemic marginal region after interventional therapy(P0.01),the RMTT significant difference(P0.05),and the RCBV no significant difference(P0.05).The RCBF RMTT and RCBV all showed no significant difference on ischemic central region after interventional therapy(P0.05).All patients had a baseline perfusion abnormality.32 of 48 cases showed improved perfusion after interventional therapy,12 cases improved obviously,3 cases no improved obviously and 1 case aggravated.Conclusion MSCTP is a new method to evaluate hemodynamic changes in patients with acute cerebral ischemia before and after interventional therapy,provide particular informations about effect evaluation.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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