Title: The Action to IL-10 and the Influence to Protein Expression of Kuijieankang Decoction to Rats' with Ulcerative Colitis
Abstract: Objective:To research into the influence of Kuijieankang decoction to rats'interleukin with ulcerative colitis and its mechanism of action.Methods:Some healthy Wistar rats were randomly divided into control group,model group,Bupiyichang pill group,SASP group,and Kuijieankang decoction group.The rat model of ulcerative colitis was established by TNBS/ethanol method.Detecting the IL-10 content and protein expression of rats'colon tissue with ulcerative colitis after intragastric administration.Results: Comparing with normal group,the IL-10 content and protein expression of model group rats descended.It was statistically significant(P0.05).The IL-10 content and protein expression of Bupiyichang pill group,SASP group,Kuijieankang decoction group rose compared to model group.Also was statistically significant(P0.05).Comparing Kuijieankang decoction group with Bupiyichang pill group and SASP group,the IL-10 content and protein expression of the former rose significantly,with statistical significance(P0.05).Conclusion:Kuijieankang decoction could heighten the IL-10 content and protein expression of rats'colon tissue with ulcerative colitis.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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